Vitamin D Supplementation Cuts Aeroallergen Sensitization

This article originally appeared here.
Share this content:
Vitamin D Supplementation Cuts Aeroallergen Sensitization
Vitamin D Supplementation Cuts Aeroallergen Sensitization

MONDAY, April 18, 2016 (HealthDay News) -- Vitamin D supplementation during pregnancy and infancy may reduce aeroallergen sensitization in children, according to a study published online April 6 in Allergy.

Cameron C. Grant, M.B.Ch.B., from the University of Auckland in New Zealand, and colleagues conducted a randomized, double-blind, placebo controlled trial. Pregnant women (27 weeks of gestation to birth) and then their infants were randomized to receive placebo or one of two doses of daily oral vitamin D (placebo/placebo; 1,000 IU/400 IU; 2,000 IU/800 IU). Specific serum immunoglobulin (Ig)E antibodies were measured when the children were 18 months old.

Specific IgE was measured in 71 percent of 260 enrolled children. The researchers found that for four mite antigens: Dermatophagoides farina (Der-f1, Der-f2) and Dermatophagoides pteronyssinus (Der-p1, Der-p2), the proportion of children sensitized varied for placebo, lower-dose, and higher-dose vitamin D, respectively: 18, 10, 2 percent; 14, 3, 2 percent; 19, 14, 3 percent; and 12, 2, 3 percent, respectively (all P < 0.05). Study group differences were seen in the proportion of children with primary care visits for asthma (11, 0, 4 percent, respectively; P = 0.002), but not for other respiratory diagnoses.

"Vitamin D supplementation during pregnancy and infancy reduces the proportion of children sensitized to mites at age 18 months," the authors write. "Preliminary data indicate a possible effect on primary care visits where asthma is diagnosed."

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters


More in Home

Pharmacists Should Counsel Patients Fasting for Ramadan

Pharmacists Should Counsel Patients Fasting for Ramadan

Pharmacists can suggest adjustments for meds taken several times per day, those affected by food intake

AUA: Many Have Unused Opioids After Urologic Procedures

AUA: Many Have Unused Opioids After Urologic Procedures

Patients use just over half of initial prescription; highest percentage of unused meds for cystectomy

Over Half of Young Adult Smoke Volume Exposure From Hookahs

Over Half of Young Adult Smoke Volume Exposure ...

Toxicant exposure to tar, carbon monoxide, nicotine lower, but still substantial, compared to cigarettes

is free, fast, and customized just for you!

Already a member?

Sign In Now »