Vitamin D Supplementation Beneficial in Rheumatoid Arthritis

This article originally appeared here.
Share this content:
Vitamin D Supplementation Beneficial in Rheumatoid Arthritis
Vitamin D Supplementation Beneficial in Rheumatoid Arthritis

TUESDAY, Oct. 27, 2015 (HealthDay News) -- For patients with active rheumatoid arthritis and vitamin D deficiency, vitamin D supplementation is associated with improved disease activity within a short period, according to a study published online Oct. 20 in the International Journal of Rheumatic Diseases.

S. Chandrashekara, M.D., and Anand Patted, M.D., from the ChanRe Rheumatology & Immunology Center & Research in Bangalore, India, and colleagues examined the correlation between vitamin D deficiency and active RA. Data were collected in an open-label intervention study involving 150 RA patients. Participants with low vitamin D levels and Disease Activity Score of 28 joints/C-reactive protein (DAS28-CRP) >2.6 were supplemented with vitamin D for 12 weeks.

The researchers found that 49 percent of the participants had DAS28-CRP >2.6 and serum vitamin D <20 ng/mL. Patients received 60,000 IU/week vitamin D supplementation for six weeks, followed by 60,000 IU/month for a total of three months. At the end of three months, disease activity and vitamin D status were assessed for 80.8 percent of patients (59 patients). There was a significant improvement in the mean DAS28-CRP of the patients, from 3.68 ± 0.93 at baseline to 3.08 ± 1.11 after supplementation (P = 0.002). During the same period, serum vitamin D level improved significantly (P < 0.001).

"Supplementation of vitamin D in RA patients with persisting disease activity and vitamin D deficiency contributed to significant improvement in disease activity within a short duration," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease



Sign up for myCME e-newsletters




More in Home

Some California Mosquitoes Can Carry Zika Virus

Some California Mosquitoes Can Carry Zika Virus

Aedes aegypti mosquitoes found to transmit Zika virus

Periodontal Inflammation a Risk With Tongue Piercing

Periodontal Inflammation a Risk With Tongue Piercing

And, two young females with tongue piercings have deep lingual infrabony lesions, periodontitis

Risk of OD Highest for First Days of Opioid  Benzodiazepine Use

Risk of OD Highest for First Days of ...

Five-fold increased risk of opioid-related overdose during first 90 days of concurrent use

is free, fast, and customized just for you!




Already a member?

Sign In Now »