Visceral Fat Differentiates Crohn's From Intestinal Tuberculosis

This article originally appeared here.
Share this content:
Visceral Fat Differentiates Crohn's From Intestinal Tuberculosis
Visceral Fat Differentiates Crohn's From Intestinal Tuberculosis

TUESDAY, March 14, 2017 (HealthDay News) -- Visceral fat (VF) quantification can differentiate Crohn's disease (CD) and intestinal tuberculosis (ITB), according to a study published in the February issue of the Journal of Gastroenterology and Hepatology.

Dawesh Prakash Yadav, M.B.B.S., M.D., from the All India Institute of Medical Sciences in New Delhi, and colleagues examined the role of VF in differentiating CD and ITB in two cohorts (development and validation). Retrospective data were collected for 75 patients with CD and ITB in the development cohort. In the validation cohort, 82 patients were recruited prospectively and were diagnosed as CD or ITB according to standard diagnostic criteria.

The researchers found that visceral fat area and the VF/subcutaneous (SC) fat ratio were significantly higher in CD than ITB patients in both the cohorts (development: 106.2 ± 63.5 versus 37.3 ± 22 [P < 0.001] and 1.1 ± 0.57 versus 0.43 ± 0.24 [P = 0.001], respectively; validation: 102.2 ± 69.8 versus 55.8 ± 44.9 [P = 0.01] and 1.2 ± 0.68 versus 0.56 ± 0.33 [P < 0.001], respectively). In the development cohort, a cut-off of 0.63 for VF/SC ratio had high sensitivity and specificity for differentiating CD and ITB (82 and 81 percent, respectively). When this cut-off was applied in the validation cohort, the sensitivity and specificity were similar (81 and 79 percent, respectively).

"The VF/SC ratio is a simple, cost-effective, non-invasive, and single objective parameter with a good sensitivity and specificity to differentiate CD and ITB," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Warns Against Children Taking Codeine, Tramadol

FDA Warns Against Children Taking Codeine, Tramadol

Agency strengthens warning labels on these medications to address dangers

Trump Administration Offers Grants to Fight Opioid Crisis

Trump Administration Offers Grants to Fight Opioid Crisis

Money to be used to train health professionals, foster prescription drug monitoring programs

NYC to Raise Cigarette Prices to Highest in the United States

NYC to Raise Cigarette Prices to Highest in ...

Price of pack to jump from $10.50 to $13.00

is free, fast, and customized just for you!

Already a member?

Sign In Now »