Vaginal Brachytherapy Cuts Mortality in Early Uterine Cancer

This article originally appeared here.
Share this content:
Vaginal Brachytherapy Cuts Mortality in Early Uterine Cancer
Vaginal Brachytherapy Cuts Mortality in Early Uterine Cancer

MONDAY, Aug. 15, 2016 (HealthDay News) -- For women with surgically staged IA or IB endometrial adenocarcinoma, use of vaginal brachytherapy (VB) is associated with a reduction in mortality, according to a study published online Aug. 10 in Cancer.

Using the National Cancer Data Base, Nicholas R. Rydzewski, from the Northwestern University Feinberg School of Medicine in Chicago, and colleagues identified 44,309 women with surgically staged IA or IB endometrial adenocarcinoma who were treated with total hysterectomy from 2003 to 2011. The authors analyzed factors associated with treatment type and performed survival analyses.

The researchers found that 88.4 percent of the 33,380 women with stage IA tumors and 51.6 percent of the 10,929 women with stage IB tumors received no radiotherapy (RT). Independent associations were seen for older age, comorbid disease, higher histologic grade, and larger tumor size with increased mortality. For both stage IA and IB disease, receipt of VB was independently associated with a reduction in mortality (hazard ratios, 0.81 and 0.62, respectively).

"Analyses of this large database support the utility of postoperative VB for many women with stage I endometrial cancer," the authors write. "Unfortunately, RT appears to be underused in this population. Greater adherence to consensus guidelines may lead to improved outcomes."

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease


Sign up for myCME e-newsletters


More in Home

Automated Central System Offers Time Savings for Pharmacists

Automated Central System Offers Time Savings for Pharmacists

Cart-fill process using new automated system is more efficient, frees up time for other roles

Therapeutic Horseback Riding Can Help Alleviate PTSD in Veterans

Therapeutic Horseback Riding Can Help Alleviate PTSD in ...

Study found statistically and clinically significant reduction in PTSD scores after six weeks of THR

Bariatric Surgery Linked to Discontinuing Diabetes Meds

Bariatric Surgery Linked to Discontinuing Diabetes Meds

Six-year antidiabetes treatment initiation rate also much lower after bariatric surgery

is free, fast, and customized just for you!

Already a member?

Sign In Now »