Vaginal Brachytherapy Cuts Mortality in Early Uterine Cancer

This article originally appeared here.
Share this content:
Vaginal Brachytherapy Cuts Mortality in Early Uterine Cancer
Vaginal Brachytherapy Cuts Mortality in Early Uterine Cancer

MONDAY, Aug. 15, 2016 (HealthDay News) -- For women with surgically staged IA or IB endometrial adenocarcinoma, use of vaginal brachytherapy (VB) is associated with a reduction in mortality, according to a study published online Aug. 10 in Cancer.

Using the National Cancer Data Base, Nicholas R. Rydzewski, from the Northwestern University Feinberg School of Medicine in Chicago, and colleagues identified 44,309 women with surgically staged IA or IB endometrial adenocarcinoma who were treated with total hysterectomy from 2003 to 2011. The authors analyzed factors associated with treatment type and performed survival analyses.

The researchers found that 88.4 percent of the 33,380 women with stage IA tumors and 51.6 percent of the 10,929 women with stage IB tumors received no radiotherapy (RT). Independent associations were seen for older age, comorbid disease, higher histologic grade, and larger tumor size with increased mortality. For both stage IA and IB disease, receipt of VB was independently associated with a reduction in mortality (hazard ratios, 0.81 and 0.62, respectively).

"Analyses of this large database support the utility of postoperative VB for many women with stage I endometrial cancer," the authors write. "Unfortunately, RT appears to be underused in this population. Greater adherence to consensus guidelines may lead to improved outcomes."

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Clinician Awareness of Exercise Addiction May Be Lacking

Clinician Awareness of Exercise Addiction May Be Lacking

Screening questions should focus on emotional connection to exercise, whether it interferes with life

Overall Vagotomy Not Linked to Risk of Parkinson's Disease

Overall Vagotomy Not Linked to Risk of Parkinson's ...

But there is a trend toward lower risk of Parkinson's for patients with truncal vagotomy

Pediatricians Missing Elevated Blood Lead Levels in U.S.

Pediatricians Missing Elevated Blood Lead Levels in U.S.

In 23 of 39 reporting states, pediatric care providers identified fewer than half of children with EBLL

is free, fast, and customized just for you!

Already a member?

Sign In Now »