U-Shaped Pattern for Dietary Calcium Intake, Fracture Risk

This article originally appeared here.
Share this content:
U-Shaped Pattern for Dietary Calcium Intake, Fracture Risk
U-Shaped Pattern for Dietary Calcium Intake, Fracture Risk

MONDAY, June 6, 2016 (HealthDay News) -- Dietary calcium intake seems to have a U-shaped correlation with fracture risk in men and possibly in women, according to a study published online May 21 in the Journal of Bone and Mineral Research.

Aiping Fang, Ph.D., from Peking University in Beijing, and colleagues examined the long-term correlations between low dietary calcium intake and fracture risk in older adults with a plant-based diet. Data were included for 6,210 Chinese men and women, aged 50 years or older, in a sub-cohort based on the China Health and Nutrition Survey.

Over a median follow-up of 7.0 years, the researchers found that 4.34 percent of men and 7.06 percent of women experienced first fracture events. For individuals in the lowest, third, and highest quintile of dietary calcium intake, the crude rates were 4.88, 2.55, and 6.83 per 1,000 person-years at risk for men and 6.72, 7.10, and 11.0 per 1,000 person-years at risk for women. For men, increased fracture risk was seen for dietary calcium intake of more than 778 mg/day (multivariate adjusted hazard ratio [HR], 2.10; 95 percent confidence interval [CI], 1.00 to 4.41) or lower than 275 mg/day (HR, 1.74; 95 percent CI, 1.00 to 3.01); for women, increased fracture risk was seen for dietary calcium intake above 651 mg/day (HR, 1.54; 95 percent CI, 1.00 to 2.38), and a nonsignificant trend of increase was seen for intake below 248 mg/day (HR, 1.00; 95 percent CI, 0.67 to 1.50).

"The patterns of dietary calcium with fracture risk are U-shaped in men and possibly in women," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Illicit Marijuana Use Up in States With Legal Medical Use

Illicit Marijuana Use Up in States With Legal ...

Cannabis use disorder is also rising faster in states with legalization laws

Chromosome Instability Test Prognostic in NSCLC

Chromosome Instability Test Prognostic in NSCLC

Chromosome instability associated with higher risk of relapse, death within 2 years

CDC: Opioid-Related Mortality Rate Might Be Underestimated

CDC: Opioid-Related Mortality Rate Might Be Underestimated

Death certificates from drug-linked infections may not label opioids as possible cause

is free, fast, and customized just for you!

Already a member?

Sign In Now »