Twin Gestation Ups Risk of Gestational Diabetes Mellitus

This article originally appeared here.
Share this content:
Twin Gestation Ups Risk of Gestational Diabetes Mellitus
Twin Gestation Ups Risk of Gestational Diabetes Mellitus

FRIDAY, June 3, 2016 (HealthDay News) -- Twin gestation is associated with increased risk of gestational diabetes mellitus (GDM), according to an article published online May 23 in Diabetes Care.

Ravi Retnakaran, M.D., from Mount Sinai Hospital in Toronto, and Baiju R. Shah, Ph.D., from the University of Toronto, examined the impact of twin gestation and the sex of both fetuses on maternal risk of diabetes during and after pregnancy. A total of 775,707 women with singleton pregnancies and 13,521 women with twins (female/female, 31.7 percent; female/male, 36.0 percent; male/male, 32.3 percent) were included in the study.

The researchers found that per 100 pregnancies, the crude rate of GDM was 5.63 in twin gestation and 3.79 in singletons. The incidence of GDM was higher in twin pregnancies after adjustment for age, income, and region of residence (adjusted odds ratio, 1.30; P < 0.001). In twin gestation, the crude rate of GDM per 100 pregnancies was 5.56, 6.08, and 5.20 for female/female, female/male, and male/male twins. Neither male/male nor male/female carried greater risk of GDM than female/female in adjusted analyses. After adjustment for confounding variables, women who had GDM with twins had lower risk of progression to diabetes than those who had GDM with singletons (adjusted hazard ratio, 0.76; P = 0.001).

"Overall, these data suggest that the impact of the twin gestation itself on maternal glucose metabolism supersedes that of fetal sex," the authors write.

Abstract
Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

FDA Approves Kinase Inhibitor for Treatment of AML

FDA Approves Kinase Inhibitor for Treatment of AML

Midostaurin, in combination with chemotherapy, treats acute myeloid leukemia in adults

Enzyme Replacement Drug OK'd for Form of Batten Disease

Enzyme Replacement Drug OK'd for Form of Batten ...

Brineura will be used to treat children with late infantile neuronal ceroid lipofuscinosis type 2 Batten

is free, fast, and customized just for you!

Already a member?

Sign In Now »