Twin Gestation Ups Risk of Gestational Diabetes Mellitus

This article originally appeared here.
Share this content:
Twin Gestation Ups Risk of Gestational Diabetes Mellitus
Twin Gestation Ups Risk of Gestational Diabetes Mellitus

FRIDAY, June 3, 2016 (HealthDay News) -- Twin gestation is associated with increased risk of gestational diabetes mellitus (GDM), according to an article published online May 23 in Diabetes Care.

Ravi Retnakaran, M.D., from Mount Sinai Hospital in Toronto, and Baiju R. Shah, Ph.D., from the University of Toronto, examined the impact of twin gestation and the sex of both fetuses on maternal risk of diabetes during and after pregnancy. A total of 775,707 women with singleton pregnancies and 13,521 women with twins (female/female, 31.7 percent; female/male, 36.0 percent; male/male, 32.3 percent) were included in the study.

The researchers found that per 100 pregnancies, the crude rate of GDM was 5.63 in twin gestation and 3.79 in singletons. The incidence of GDM was higher in twin pregnancies after adjustment for age, income, and region of residence (adjusted odds ratio, 1.30; P < 0.001). In twin gestation, the crude rate of GDM per 100 pregnancies was 5.56, 6.08, and 5.20 for female/female, female/male, and male/male twins. Neither male/male nor male/female carried greater risk of GDM than female/female in adjusted analyses. After adjustment for confounding variables, women who had GDM with twins had lower risk of progression to diabetes than those who had GDM with singletons (adjusted hazard ratio, 0.76; P = 0.001).

"Overall, these data suggest that the impact of the twin gestation itself on maternal glucose metabolism supersedes that of fetal sex," the authors write.

Abstract
Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

SABCS: Artificial Intelligence May Aid Doctors in Breast Cancer Care

SABCS: Artificial Intelligence May Aid Doctors in Breast ...

'Watson Oncology' agreed with doctors 90 percent of the time in many cases, researchers find

SABCS: Scalp-Cooling System Can Reduce Chemo-Related Hair Loss

SABCS: Scalp-Cooling System Can Reduce Chemo-Related Hair Loss

Devices reduce blood flow to hair follicles during chemotherapy treatments

SABCS: Aromatase Inhibitors Tied to Reduced Endothelial Function

SABCS: Aromatase Inhibitors Tied to Reduced Endothelial Function

Women on aromatase inhibitors exhibit less elasticity in their blood vessels

is free, fast, and customized just for you!

Already a member?

Sign In Now »