Thyroid Status Linked to Impaired HRQoL in Dialysis Patients

This article originally appeared here.
Share this content:
Thyroid Status Linked to Impaired HRQoL in Dialysis Patients
Thyroid Status Linked to Impaired HRQoL in Dialysis Patients

FRIDAY, July 14, 2017 (HealthDay News) -- For hemodialysis patients, thyroid status is associated with impaired health-related quality of life (HRQoL), according to a study published online July 13 in the Clinical Journal of the American Society of Nephrology.

Connie M. Rhee, M.D., from the University of California Irvine, and colleagues examined the correlation of thyroid status, defined by serum thyrotropin (TSH), with HRQoL and depressive symptoms over time in a cohort of 450 hemodialysis patients from 17 outpatient dialysis facilities. Participants completed protocolized TSH testing, Short-Form 36 (SF-36) surveys, and Beck Depression Inventory-II questionnaires.

The researchers observed a correlation for the highest baseline TSH tertile with a 5-point lower SF-36 domain score for energy/fatigue (P = 0.04), and a correlation for the highest time-dependent tertile with a 5-point lower physical function score (P = 0.03). Higher baseline TSH levels correlated with lower role limitations due to physical health, energy/fatigue, and pain scores (P = 0.04, 0.03, and 0.002, respectively), which was equivalent to scores that were 5, 3, and 5 points lower for every one standard deviation (SD) higher TSH. There was a correlation seen for higher time-dependent TSH levels with lower role limitations due to physical health scores (P = 0.03), which was equivalent to a decrease of 3 points for every one SD higher TSH.

"Studies are needed to determine if thyroid-modulating therapy improves the HRQoL of hemodialysis patients with thyroid dysfunction," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

Even Overdose Doesn't Stop Opioid Prescribing

Even Overdose Doesn't Stop Opioid Prescribing

Few receive medication-assisted treatment after hospital discharge, researchers find

NT-ProBNP-Guided Treatment No Benefit in High-Risk HFrEF

NT-ProBNP-Guided Treatment No Benefit in High-Risk HFrEF

No improvement in clinical outcomes versus usual care in heart failure and reduced ejection fraction

Oral Corticosteroids No Benefit for LRI in Non-Asthmatic Adults

Oral Corticosteroids No Benefit for LRI in Non-Asthmatic ...

No decrease in cough duration, severity for adults without asthma with lower respiratory tract symptom

is free, fast, and customized just for you!

Already a member?

Sign In Now »