Thyroid Function Level Linked to Breast Cancer Risk

This article originally appeared here.
Share this content:
Thyroid Function Level Linked to Breast Cancer Risk
Thyroid Function Level Linked to Breast Cancer Risk

WEDNESDAY, Feb. 17, 2016 (HealthDay News) -- Women with hyperthyroidism have increased breast cancer risk, while hypothyroidism is associated with decreased risk, according to a study published in the April 1 issue of the European Journal of Endocrinology.

Mette Søgaard, Ph.D., from Aarhus University Hospital in Denmark, and colleagues examined the correlation between thyroid disease and breast cancer in a population-based cohort study. All women in Denmark with a first-time hospital diagnosis of hypothyroidism or hyperthyroidism in 1978 to 2013 were identified. The excess risk of breast cancer was compared for patients with hypothyroidism or hyperthyroidism versus the expected risk in the general population. To avoid diagnostic work-up bias, breast cancer diagnoses in the first 12 months following thyroid disease diagnosis were excluded.

The researchers note that 61,873 and 80,343 women were diagnosed with hypothyroidism and hyperthyroidism, respectively. Compared with the general population, hyperthyroidism correlated with a slightly increased risk of breast cancer (standardized incidence ratio [SIR], 1.11; 95 percent confidence interval [CI], 1.07 to 1.16), which persisted beyond five years of follow-up (SIR, 1.13; 95 percent CI, 1.08 to 1.19). Hypothyroidism correlated with a lower breast cancer risk (SIR, 0.94; 95 percent CI, 0.88 to 1.00).

"We found an increased risk of breast cancer in women with hyperthyroidism and a slightly decreased risk in women with hypothyroidism indicating an association between thyroid function level and breast cancer risk," the authors write.

The study was partially funded by the Program for Clinical Research Infrastructure, established by the Lundbeck and Novo Nordisk Foundations.

Abstract
Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters


More in Home

Surveillance Frequency Doesn't Cut Mortality in Colorectal Cancer

Surveillance Frequency Doesn't Cut Mortality in Colorectal Cancer

And, intensity of imaging surveillance not linked to time to detection of colorectal cancer recurrence

Procalcitonin Assay Doesn't Cut Antibiotic Use in Lower RTI

Procalcitonin Assay Doesn't Cut Antibiotic Use in Lower ...

Provision of assay doesn't result in less antibiotic use for suspected lower respiratory tract infection

Preventing Child Maltreatment Not Yet Feasible in Primary Care

Preventing Child Maltreatment Not Yet Feasible in Primary ...

USPSTF says evidence inadequate for primary care interventions to prevent child maltreatment

is free, fast, and customized just for you!

Already a member?

Sign In Now »