Testosterone Solution Found Safe, Effective for Hypogonadal Men

This article originally appeared here.
Share this content:
Testosterone Solution Found Safe, Effective for Hypogonadal Men
Testosterone Solution Found Safe, Effective for Hypogonadal Men

MONDAY, Aug. 22, 2016 (HealthDay News) -- Once-daily 2 percent testosterone solution (T-sol) is safe and effective for sex drive and energy in hypogonadal men, according to a study published online in The Journal of Urology.

Gerald Brock, M.D., from the University of Western Ontario in London, Canada, and colleagues examined the continued safety and efficacy of T-sol in a six-month open-label extension study following a three-month placebo controlled study. Five hundred fifty-eight hypogonadal participants (mean age, 55 years) were enrolled in the open-label study. Of these, 275 and 283 had previously received placebo and T-sol, respectively, in the double-blind phase.

The researchers found that 60 and 66 percent of the participants in the formerly placebo and continuing active treatment groups, respectively, had total testosterone levels within the normal range at the completion of the open-label phase. During the open-label phase, there were baseline to end point improvements for both groups in the Sexual Arousal, Interest, and Drive score (both P < 0.001) and Hypogonadism Energy Diary score (both P < 0.001). There were no reports of new safety concerns.

"Once-daily T-sol administered for six months in an open-label study did not indicate new safety concerns, and the outcomes of low sex drive and low energy showed further improvement after the double-blind phase," the authors write.

Several authors disclosed financial ties to pharmaceutical companies, including Eli Lilly, which assisted with trial administration.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease



Sign up for myCME e-newsletters




More in Home

High Success Rates for Mitral Valve Repair With Robotic Surgery

High Success Rates for Mitral Valve Repair With ...

Minimally invasive surgery linked to fewer discharges to facility, one day less in hospital vs conservative sx

Tattoo-Linked Complications ID'd in Immunosuppressed Female

Tattoo-Linked Complications ID'd in Immunosuppressed Female

Inflammatory myopathy identified in woman with cystic fibrosis on long-term immunosuppressants

Rates of Cardiac Stress Testing Down but Still Higher in CKD

Rates of Cardiac Stress Testing Down but Still ...

Decline in rates of cardiac stress testing in Medicare beneficiaries aged ≥66 years from 2008 to 2012

is free, fast, and customized just for you!




Already a member?

Sign In Now »