Target-Vessel Failure Rate Similar for Scaffold, Stent in PCI

This article originally appeared here.
Share this content:
Target-Vessel Failure Rate Similar for Scaffold, Stent in PCI
Target-Vessel Failure Rate Similar for Scaffold, Stent in PCI

THURSDAY, March 30, 2017 (HealthDay News) -- For patients undergoing percutaneous coronary intervention (PCI), the rate of target-vessel failure does not differ significantly for those receiving a bioresorbable vascular scaffold or a metallic stent, according to a study published online March 29 in the New England Journal of Medicine.

Joanna J. Wykrzykowska, M.D., Ph.D., from the Academic Medical Center-University of Amsterdam, and colleagues randomized patients undergoing PCI to receive a bioresorbable vascular scaffold or a metallic stent (924 and 921 patients, respectively). Target-vessel failure (a composite of cardiac death, target-vessel myocardial infarction, or target-vessel revascularization) was assessed as the primary end point.

The researchers found that the two-year cumulative event rates for target-vessel failure were 11.7 and 10.7 percent in the scaffold and stent groups, respectively (hazard ratio, 1.12; 95 percent confidence interval, 0.85 to 1.48; P = 0.43). The two-year cumulative event rates were 2.0 and 2.7 percent, respectively, for cardiac death; 5.5 and 3.2 percent, respectively, for target-vessel myocardial infarction, and 8.7 and 7.5 percent, respectively, for target-vessel revascularization. The two-year cumulative event rates were 3.5 and 0.9 percent for the scaffold and stent groups, respectively, for definite or probable device thrombosis (hazard ratio, 3.87; 95 percent confidence interval, 1.78 to 8.42; P < 0.001).

"There was no significant difference in the rate of target-vessel failure between the patients who received a bioresorbable scaffold and the patients who received a metallic stent," the authors write.

The study was funded by Abbott Vascular.

Abstract
Full Text
Editorial

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

Air Pollution May Damage Kidneys

Air Pollution May Damage Kidneys

Study finds link between particulate matter and renal function

Diabetes Treatment Failure May Actually Be Nonadherence

Diabetes Treatment Failure May Actually Be Nonadherence

Second-line treatment often initiated without evidence of recommended use of first-line treatment

Effect of Osteoporotic Fractures Similar to Diabetes Burden

Effect of Osteoporotic Fractures Similar to Diabetes Burden

Findings for quality of life with hip fractures, vertebral compression vs. vision loss, amputation

is free, fast, and customized just for you!

Already a member?

Sign In Now »