Sleep Quality, Duration Linked to CKD Progression

This article originally appeared here.
Share this content:
Sleep Quality, Duration Linked to CKD Progression
Sleep Quality, Duration Linked to CKD Progression

FRIDAY, Sept. 15, 2017 (HealthDay News) -- Shorter sleep duration and poor sleep quality are associated with progression of chronic kidney disease (CKD), according to a study published online Sept. 14 in the Journal of the American Society of Nephrology.

Ana C. Ricardo, M.D., from the University of Illinois at Chicago, and colleagues examined the correlation of habitual sleep duration and quality with progression of CKD in 431 participants in the Chronic Renal Insufficiency Cohort.

Participants slept an average of 6.5 hours/night, with mean sleep fragmentation of 21 percent. The researchers identified 70 end-stage renal disease (ESRD) events and 48 deaths over a median follow-up of five years. Greater sleep fragmentation was associated with increased ESRD risk (hazard ratio, 1.04 per 1 percent increase in fragmentation), in adjusted analyses. Shorter sleep duration (per hour less) and greater sleep fragmentation (per 1 percent more) correlated with greater decline in estimated glomerular filtration rate (−1.12 and 0.18 ml/min/1.73 m²/year, respectively) and greater log-urine protein-to-creatinine ratio slope (0.06 and 0.01/year, respectively), in adjusted models. In the fully-adjusted model, self-reported daytime sleepiness correlated with increased risk for all-cause death (hazard ratio, 1.11 per one-point increase in Epworth Sleepiness Scale).

"These findings suggest that short and poor quality sleep are unrecognized risk factors for CKD progression," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions


Sign up for myCME e-newsletters


More in Home

Structural Findings of Acute Solar Retinopathy Described

Structural Findings of Acute Solar Retinopathy Described

Patient in case study presented three days after viewing solar eclipse

Telomere Fusions Predict Dysplasia, Invasive Pancreatic CA

Telomere Fusions Predict Dysplasia, Invasive Pancreatic CA

Telomere fusions are detected in later stages of intraductal papillary mucinous neoplasm progression

Prenatal Sugar Intake May Increase Asthma Risk in Offspring

Prenatal Sugar Intake May Increase Asthma Risk in ...

Higher intake during pregnancy, in early childhood associated with childhood asthma development

is free, fast, and customized just for you!

Already a member?

Sign In Now »