Severe Cerebral Damage ID'd on Imaging in Children With Zika

Share this content:
Severe Cerebral Damage ID'd on Imaging in Children With Zika
Severe Cerebral Damage ID'd on Imaging in Children With Zika

FRIDAY, April 15, 2016 (HealthDay News) -- Children with congenital infection, presumably associated with the Zika virus, have severe cerebral damage identified on imaging, according to a study published online April 13 in The BMJ.

Maria de Fatima Vasco Aragao, M.D., from the Mauricio de Nassau University in Brazil in Recife, and colleagues reported radiologic findings from computed tomography (CT) and magnetic resonance imaging (MRI) brain scans in 23 children with a diagnosis of congenital infection, presumably associated with the Zika virus.

The researchers found that six of the children tested positive for immunoglobulin (Ig)M antibodies to Zika virus in the cerebrospinal fluid. The other 17 children were not tested for IgM antibodies, but met the protocol criteria for congenital infection presumably associated with Zika virus. Fifteen of the children underwent CT, seven underwent CT and MRI, and one underwent MRI only. All 22 children who underwent CT had calcifications in the junction between cortical and subcortical white matter; and 21, 20, 19, and 11, respectively, had malformations of cortical development, decreased brain volume, ventriculomegaly, and hypoplasia of the cerebellum or brainstem. All eight children who underwent MRI had calcifications in the junction between cortical and subcortical white matter, malformations of cortical development (mainly in the frontal lobe), and ventriculomegaly.

"This study shows the largest and most detailed case series of neuroimaging findings in children with microcephaly and presumed Zika virus-related infection to date," the authors write.

Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters


More in Home

Surveillance Frequency Doesn't Cut Mortality in Colorectal Cancer

Surveillance Frequency Doesn't Cut Mortality in Colorectal Cancer

And, intensity of imaging surveillance not linked to time to detection of colorectal cancer recurrence

Procalcitonin Assay Doesn't Cut Antibiotic Use in Lower RTI

Procalcitonin Assay Doesn't Cut Antibiotic Use in Lower ...

Provision of assay doesn't result in less antibiotic use for suspected lower respiratory tract infection

Preventing Child Maltreatment Not Yet Feasible in Primary Care

Preventing Child Maltreatment Not Yet Feasible in Primary ...

USPSTF says evidence inadequate for primary care interventions to prevent child maltreatment

is free, fast, and customized just for you!

Already a member?

Sign In Now »