September 2017 Briefing - Cardiology

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Here are what the editors at HealthDay consider to be the most important developments in Cardiology for September 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Embezzlement Widespread in Medical Practices

FRIDAY, Sept. 29, 2017 (HealthDay News) -- Embezzlement is widespread among medical practices, and knowing the warning signs is helpful for preventing it, according to an article published in Medical Economics.

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Pioglitazone Improves Left Ventricular Diastolic Function

FRIDAY, Sept. 29, 2017 (HealthDay News) -- Pioglitazone improves whole-body and myocardial insulin sensitivity, left ventricular (LV) diastolic function, and systolic function in patients with type 2 diabetes, according to a small study published online Sept. 22 in Diabetes Care.

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Meditation May Help With Cardiovascular Risk Reduction

FRIDAY, Sept. 29, 2017 (HealthDay News) -- Meditation may be considered as an adjunct to guideline-directed cardiovascular risk reduction, although the benefits need to be more fully established, according to a scientific statement published online Sept. 28 in the Journal of the American Heart Association.

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End-Stage Renal Disease Patients' Readmission Rate High

FRIDAY, Sept. 29, 2017 (HealthDay News) -- Nearly a quarter of hospital admissions among patients with end-stage renal disease (ESRD) on hemodialysis (HD) have a subsequent 30-day unplanned readmission, according to a study published online Sept. 28 in the Clinical Journal of the American Society of Nephrology.

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More Than 78 Percent of Health Care Personnel Receive Flu Shot

THURSDAY, Sept. 28, 2017 (HealthDay News) -- More than 78 percent of health care personnel (HCP) and 53.6 percent of pregnant women received influenza vaccination during the 2016-2017 influenza season, according to two studies published in the Sept. 29 issue of Morbidity and Mortality Weekly Report.

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About Half of Patients Receive Approval for PCSK9i Prescription

WEDNESDAY, Sept. 27, 2017 (HealthDay News) -- Fewer than half of patients prescribed PCSK9 inhibitors (PCSK9i) receive approval, and only about 30 percent ever receive therapy, according to a study published online Sept. 27 in JAMA Cardiology.

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Cardiometabolic Risk, HOMA-IR Up With Increasing BMI in Young

WEDNESDAY, Sept. 27, 2017 (HealthDay News) -- Cardiometabolic risk and homeostatic model assessment (HOMA) of insulin resistance (IR) increase with increasing body mass index (BMI) categories among children, and cardiorespiratory fitness (CRF) may attenuate the risk, according to a study published online Sept. 14 in Diabetes Care.

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Infusion of Umbilical Cord Stem Cells Safe, Effective in HFrEF

WEDNESDAY, Sept. 27, 2017 (HealthDay News) -- Intravenous infusion of umbilical cord-derived mesenchymal stem cells (UC-MSCs) is safe and efficacious for patients with heart failure and reduced ejection fraction (HFrEF), according to a study published online Sept. 26 in Circulation Research.

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Individualized SBP Tx Cuts Risk for Post-Op Organ Dysfunction

WEDNESDAY, Sept. 27, 2017 (HealthDay News) -- Management targeting an individualized systolic blood pressure (SBP) is associated with reduced risk of organ dysfunction among patients undergoing major surgery who are at increased risk of postoperative complications, according to a study published in the Sept. 26 issue of the Journal of the American Medical Association.

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Working With a Scribe Improves Physician Satisfaction

WEDNESDAY, Sept. 27, 2017 (HealthDay News) -- Working with a scribe significantly improves physicians' overall satisfaction, satisfaction with chart quality and accuracy, and charting efficiency, according to a study published online Sept. 11 in the Annals of Family Medicine.

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Fragmented QRS Predicts Cardiac Death During Exercise

WEDNESDAY, Sept. 27, 2017 (HealthDay News) -- Fragmented QRS complex may predict risk of exercise-related sudden cardiac death, according to a study published online Sept. 20 in the Journal of Cardiovascular Electrophysiology.

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Bayesian Method Useful for Noncompleters of 400-m Walk

TUESDAY, Sept. 26, 2017 (HealthDay News) -- A Bayesian multiple imputation (MI) method is useful for calculating the speeds of those who are unable to complete the 400-m walk test within the time constraint (noncompleters), according to a study published online Sept. 8 in the Journal of the American Geriatrics Society.

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Low-Dose Oxygen No Benefit in Adults With Acute Stroke

TUESDAY, Sept. 26, 2017 (HealthDay News) -- The prophylactic use of low-dose oxygen does not reduce death or disability at three months among patients with acute stroke, according to a study published in the Sept. 26 issue of the Journal of the American Medical Association.

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Nut Consumption Linked to Nutritionally Rich Food Intake

TUESDAY, Sept. 26, 2017 (HealthDay News) -- Among overweight and obese women, nut consumption is associated with increased consumption of nutritionally rich foods and with reduced body mass index (BMI), according to a study published online Sept. 21 in the U.S. Centers for Disease Control and Prevention's Preventing Chronic Disease.

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Predictors of Death in Cirrhosis Include Age, BSA, MELD

TUESDAY, Sept. 26, 2017 (HealthDay News) -- For patients with cirrhosis, predictors of death include age, body surface area (BSA), and Model for End-Stage Liver Disease (MELD), according to a study published online Sept. 13 in Hepatology.

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Discontinuing Low-Dose Aspirin Ups Cardiovascular Risk

MONDAY, Sept. 25, 2017 (HealthDay News) -- There is more than a 30 percent increased risk of cardiovascular events following discontinuation of low-dose aspirin in long-term users, according to a study published in the Sept 26 issue of Circulation.

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Physical Activity Tied to Lower Mortality, CVD on Global Level

MONDAY, Sept. 25, 2017 (HealthDay News) -- On a global level, higher recreational and non-recreational physical activity is associated with a lower risk of mortality and cardiovascular disease (CVD) events, according to a large study published Sept. 21 in The Lancet.

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Worker Contribution to Health Benefits Up in 2017

MONDAY, Sept. 25, 2017 (HealthDay News) -- In 2017, health benefits coverage remained stable, while workers faced considerable variation in costs, according to a report published online Sept. 19 in Health Affairs.

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Insulin Dose Not Tied to Cardiovascular Outcomes

MONDAY, Sept. 25, 2017 (HealthDay News) -- Cardiovascular outcomes in patients with diabetes are not explained by insulin resistance, according to research published online Sept. 12 in Diabetes, Obesity and Metabolism.

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APOE Allele Type Tied to Mortality Risk

FRIDAY, Sept. 22, 2017 (HealthDay News) -- The apolipoprotein E (APOE) ε4 allele increases the risk of overall and cardiovascular mortality, while the APOE ε2 allele decreases the risk, according to a study published online Sept. 12 in the Journal of the American Geriatrics Society.

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Fasting Blood Glucose Trajectory May Predict Future MI

FRIDAY, Sept. 22, 2017 (HealthDay News) -- For individuals without diabetes, certain fasting blood glucose (FBG) trajectories are associated with the risk of future myocardial infarction (MI), according to a study published online Sept. 8 in Diabetes Care.

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Few Older Patients Aware of Deprescribing

FRIDAY, Sept. 22, 2017 (HealthDay News) -- The majority of older patients are aware of medication harms, but far fewer understand deprescribing, according to a brief report published online Sept. 15 in the Journal of the American Geriatrics Society.

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Pulse Ox + Auscultation Reliable for Congenital Heart Screening

FRIDAY, Sept. 22, 2017 (HealthDay News) -- Pulse oximetry (POX) plus cardiac auscultation is a reliable method for neonatal congenital heart disease screening, according to a study published online Sept. 22 in Pediatrics.

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Nonadherence to Statins + ACEIs/ARBs Risky Post MI

FRIDAY, Sept. 22, 2017 (HealthDay News) -- Nonadherence to angiotensin-converting enzyme (ACE) inhibitors/angiotensin II receptor blockers (ARBs) and/or statins following acute myocardial infarction (AMI) is associated with higher mortality, according to study published in the Sept. 26 issue of the Journal of the American College of Cardiology.

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Insurer Market Power Lowers Providers' Prices

WEDNESDAY, Sept. 20, 2017 (HealthDay News) -- Insurers have the bargaining power to reduce provider prices in highly concentrated provider markets, according to a report published in the September issue of Health Affairs.

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Type 2 Myocardial Infarction Definition Impacts Prognosis

WEDNESDAY, Sept. 20, 2017 (HealthDay News) -- Definition of type 2 myocardial infarction (T2MI) using a method that does not require the presence of coronary artery disease is associated with a lower event-related mortality rate, according to a study published in the Sept. 26 issue of the Journal of the American College of Cardiology.

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Attempts to Prevent Tongue Swallowing Hinder Resuscitation

WEDNESDAY, Sept. 20, 2017 (HealthDay News) -- For athletes with cardiac arrest, attempts to prevent tongue swallowing are an obstacle to resuscitation, according to a study published online Sept. 19 in HeartRhythm.

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Multicomponent Intervention Linked to Greater Drop in BP

TUESDAY, Sept. 19, 2017 (HealthDay News) -- A multicomponent intervention is associated with greater reduction in systolic and diastolic blood pressure (BP) than usual care over 18 months, according to a study published in the Sept. 19 issue of the Journal of the American Medical Association.

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Deaths, Cardiac Arrest Not Rare in Triathlon Participants

TUESDAY, Sept. 19, 2017 (HealthDay News) -- The incidence of deaths or cardiac arrest is 1.74 per 100,000 USA Triathlon participants, according to a study published online Sept. 19 in the Annals of Internal Medicine.

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ACP Does Not Support Legalization of Assisted Suicide

TUESDAY, Sept. 19, 2017 (HealthDay News) -- The American College of Physicians (ACP) does not support the legalization of physician-assisted suicide, a practice that raises ethical, clinical, and other concerns, according to a position paper published online Sept. 19 in the Annals of Internal Medicine.

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Anagliptin Effect on LDL in T2DM Via ApoB-100 Synthesis

TUESDAY, Sept. 19, 2017 (HealthDay News) -- In patients with type 2 diabetes being treated with a dipeptidyl peptidase-4 inhibitor (DPP4-I), use of anagliptin (ANA) may improve low-density lipoprotein cholesterol (LDL-C) levels, with the effect mediated, at least partly, via suppression of apoB-100 synthesis, according to a study published online Aug. 29 in the Journal of Diabetes Investigation.

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Greater Benefit for Pioglitazone in High-Risk Patients Post Stroke

MONDAY, Sept. 18, 2017 (HealthDay News) -- For patients after an ischemic stroke or transient ischemic attack, pioglitazone is associated with greater benefit for those at higher risk for stroke or myocardial infarction (MI), according to a study published online Sept. 18 in JAMA Neurology.

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Postmarketing Adverse Events Low for CardioMEMS HF System

MONDAY, Sept. 18, 2017 (HealthDay News) -- Postmarketing adverse events related to the CardioMEMS HF System are infrequent, but can be serious, according to a research letter published online Sept. 18 in JAMA Cardiology.

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Physicians Tweeting About Drugs May Have Conflict of Interest

FRIDAY, Sept. 15, 2017 (HealthDay News) -- Most physicians on Twitter with a financial conflict of interest (FCOI) and frequent tweets mention specific drugs for which they have a conflict, according to a study published in the September issue of The Lancet Haematology.

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Lower Mortality Risk Seen With Statin Use in Older Men

FRIDAY, Sept. 15, 2017 (HealthDay News) -- Statin use is associated with a significantly lower risk of mortality in older male physicians, and a non-significant lower risk of cardiovascular disease (CVD) events, according to a study published online Sept. 11 in the Journal of the American Geriatrics Society.

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Doctors Spend Almost Six Hours Per Day on EHR Tasks

FRIDAY, Sept. 15, 2017 (HealthDay News) -- Physicians spend almost six hours per day in the electronic health record (EHR), with 4.5 hours spent during clinic hours and 1.4 hours spent after clinic hours, according to a study published in the September/October issue of the Annals of Family Medicine.

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Hospital Quality Independently Impacts Readmission Rates

FRIDAY, Sept. 15, 2017 (HealthDay News) -- Hospital quality contributes to readmission rates independent of factors involving patients, according to a study published in the Sept. 14 issue of the New England Journal of Medicine.

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'Science Spin' Found Prevalent in Biomedical Literature

FRIDAY, Sept. 15, 2017 (HealthDay News) -- Spin in biomedical literature (also referred to as "science hype") is prevalent, with trials having the highest and greatest variability in the prevalence of spin, according to a review published online Sept. 11 in PLOS Biology.

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Ablating Non-Pulmonary Vein Triggers Improves A-Fib Outcome

THURSDAY, Sept. 14, 2017 (HealthDay News) -- For patients with atrial fibrillation (AF) with two or more failed pulmonary vein isolation (PVI) procedures, ablating non-PV triggers is associated with improved outcomes, according to a study published online Aug. 25 in the Journal of Cardiovascular Electrophysiology.

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Some Aspects of Empathy Improve During Medical Training

WEDNESDAY, Sept. 13, 2017 (HealthDay News) -- Certain aspects of empathy improve during medical student training, according to a study published online Sept. 7 in Medical Education.

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Are Physicians Obligated to Help on Planes?

TUESDAY, Sept. 12, 2017 (HealthDay News) -- Does being a physician carry a moral obligation to respond to calls for medical assistance on airplanes? That is the topic of an article published in the Sept. 12 issue of the Journal of the American Medical Association.

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Hormone Therapy in Menopause Not Tied to Increased Mortality

TUESDAY, Sept. 12, 2017 (HealthDay News) -- Menopausal hormone therapy is not tied to any increase in long-term all-cause or cause-specific mortality, according to a study published in the Sept. 12 issue of the Journal of the American Medical Association.

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Distal Bicep Tendon Rip Tied to Transthyretin Amyloidosis

TUESDAY, Sept. 12, 2017 (HealthDay News) -- Rupture of the distal biceps tendon (RBT) in a patient with heart failure with preserved ejection fraction should raise suspicion for wild-type transthyretin amyloidosis (ATTRwt), according to a research letter published in the Sept. 12 issue of the Journal of the American Medical Association.

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Cardiac Disease Events Up in Metabolically Healthy Obese

TUESDAY, Sept. 12, 2017 (HealthDay News) -- Metabolically healthy obese individuals have increased risk of coronary heart disease, cerebrovascular disease, and heart failure compared with normal-weight individuals, according to a study published in the Sept. 19 issue of the Journal of the American College of Cardiology.

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Warfarin, Rivaroxaban Similarly Safe, Effective

TUESDAY, Sept. 12, 2017 (HealthDay News) -- For cases of mild atrial fibrillation (AF)-related acute ischemic stroke, rivaroxaban and warfarin are similarly safe and effective at preventing recurrent stroke, according to a study published online Sept. 11 in JAMA Neurology.

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Sedentary Time Volume, Accrual Linked to All-Cause Mortality

TUESDAY, Sept. 12, 2017 (HealthDay News) -- Sedentary time volume and its accrual in prolonged, uninterrupted bouts are associated with increased risk of all-cause mortality, according to a study published online Sept. 12 in the Annals of Internal Medicine.

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Greater Height Tied to Higher Risk of Venous Thromboembolism

MONDAY, Sept. 11, 2017 (HealthDay News) -- Height is an independent predictor of venous thromboembolism (VTE), according to a study published online Sept. 5 in Circulation: Cardiovascular Genetics.

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Socioeconomic Conditions Affect Metabolic Syndrome Risk

FRIDAY, Sept. 8, 2017 (HealthDay News) -- Cardiometabolic risk in young blacks is influenced by broad economic conditions, according to a study published online Sept. 6 in the Journal of the American Heart Association.

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Center Surgical Volume Linked to LVAD Patient Outcomes

FRIDAY, Sept. 8, 2017 (HealthDay News) -- Center surgical volume is associated with left ventricular assist device (LVAD) patient outcomes, with worse survival at very-low-volume centers, according to a study published online Sept. 6 in JACC: Heart Failure.

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Statins Tied to Reduced Mortality Risk in COPD

FRIDAY, Sept. 8, 2017 (HealthDay News) -- Statin use is associated with a reduced risk of all-cause and pulmonary-related mortality in patients with chronic obstructive pulmonary disease (COPD), according to a study published online Sept. 7 in Chest.

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Intensive BP Control Associated With Increased CKD Risk

THURSDAY, Sept. 7, 2017 (HealthDay News) -- Intensive systolic blood pressure (SBP) lowering is associated with an increased risk of chronic kidney disease (CKD) events but a reduced risk of cardiovascular events and mortality, according to a study published online Sept. 4 in the Annals of Internal Medicine.

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Knowledge on Primary Prevention ICD Use Found Lacking

WEDNESDAY, Sept. 6, 2017 (HealthDay News) -- Referring physicians have limited knowledge regarding indications for primary prevention implantable defibrillator (ICD) use, according to a study published online Aug. 25 in the Journal of Cardiovascular Electrophysiology.

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Sudden Cardiac Arrest After Food Linked to Brugada Syndrome

WEDNESDAY, Sept. 6, 2017 (HealthDay News) -- Having a sudden cardiac arrest after eating a large bite of food may be an indication of Brugada syndrome, according to a case study published online Sept. 6 in Pediatrics.

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Docs Should Be Aware of Family Beliefs Regarding Nondisclosure

WEDNESDAY, Sept. 6, 2017 (HealthDay News) -- Physicians should be aware of societal codes of conduct that affect family beliefs and behaviors regarding information disclosure to pediatric patients, according to a study published online Sept. 5 in JAMA Pediatrics.

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New Appropriate Use Criteria Issued for Valvular Heart Disease

TUESDAY, Sept. 5, 2017 (HealthDay News) -- Appropriate use criteria have been developed for valvular heart disease imaging tests, according to a report published online Sept. 1 in the Journal of the American College of Cardiology.

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More Research Needed for Vitamin D's Cardiac Effect in PCI

TUESDAY, Sept. 5, 2017 (HealthDay News) -- More research is needed to assess the role of vitamin D in the prevention of periprocedural myocardial injury, according to a study published online Aug. 25 in the Journal of Clinical Pharmacology.

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Benefit of Aspirin After A-Fib Ablation Questioned

FRIDAY, Sept. 1, 2017 (HealthDay News) -- For atrial fibrillation (AF) ablation patients undergoing their index ablation, long-term aspirin therapy is associated with increased rates of bleeding and may not lower risk of stroke, according to a study published online Aug. 28 in the Journal of Cardiovascular Electrophysiology.

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Coronary Artery Calcium May Be Best Indicator of CVD Risk

FRIDAY, Sept. 1, 2017 (HealthDay News) -- The cardiovascular event rate is low for patients with no coronary artery calcium (CAC), which improves overall prediction among patients thought to be at risk of atherosclerotic cardiovascular disease (ASCVD), according to a letter to the editor published in the Aug. 1 issue of JACC: Cardiovascular Imaging.

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Electronic Alert Doesn't Up Appropriate Thromboprophylaxis

FRIDAY, Sept. 1, 2017 (HealthDay News) -- A computer-based alert system with a Geneva Risk Score calculation tool in the electronic patient chart does not improve appropriate thromboprophylaxis in patients admitted to general medical wards, according to a study published online Aug. 24 in the Journal of Thrombosis and Haemostasis.

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Low Incidence of Adverse Events for A-Fib Catheter Ablation

FRIDAY, Sept. 1, 2017 (HealthDay News) -- The incidence of adverse events (AEs) is low for patients undergoing catheter ablation (CA) for atrial fibrillation (AF), according to a study published online Aug. 30 in JACC: Clinical Electrophysiology.

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Suicide Risk Up in Younger Patients With Chronic Illness

FRIDAY, Sept. 1, 2017 (HealthDay News) -- Young adults with chronic diseases like asthma and diabetes are more than four times as likely to attempt suicide as their healthy peers, according to a study published online Aug. 17 in the Canadian Journal of Psychiatry.

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