September 2015 Briefing - Diabetes & Endocrinology

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for September 2015. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

More Support for High-Fiber, Mediterranean Diet

WEDNESDAY, Sept. 30, 2015 (HealthDay News) -- Numerous studies have extolled the health benefits of the Mediterranean diet. Now, research suggests the regimen may also increase levels of beneficial short-chain fatty acids (SCFAs). The findings were published online Sept. 29 in Gut.

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Gene Variant May Boost Effect of Higher-Protein Diet in T2DM

WEDNESDAY, Sept. 30, 2015 (HealthDay News) -- Patients with type 2 diabetes may benefit from a higher-protein diet, but it may depend on whether or not they have a particular gene related to vitamin D metabolism, new research suggests. The study was published online Sept. 29 in Diabetologia.

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Calcium Supplements May Not Benefit Bone Health

WEDNESDAY, Sept. 30, 2015 (HealthDay News) -- Extra calcium may not protect aging bones after all. The findings appear online in two reviews published online Sept. 29 in The BMJ.

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Nocturnal Hypoglycemia Linked to Reduced Awakening Response

WEDNESDAY, Sept. 30, 2015 (HealthDay News) -- Nocturnal hypoglycemia is associated with reduced awakening response, according to a study published online Sept. 25 in Diabetes Care.

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Negative Spiritual Belief Linked to Worse Health Outcomes

WEDNESDAY, Sept. 30, 2015 (HealthDay News) -- Any degree of negative spiritual belief is associated with worse health outcomes, regardless of positive spiritual beliefs, according to a study published in the Journal of Spirituality in Mental Health.

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Angioedema Induced by New Classes of Drugs

WEDNESDAY, Sept. 30, 2015 (HealthDay News) -- Two newer classes of drugs, dipeptidyl peptidase IV (DPP IV) and neprilysin inhibitors, can induce angioedema, according to research published in the October issue of Allergy.

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Nomogram Predicts Death, Recurrence With Thyroid Cancer

WEDNESDAY, Sept. 30, 2015 (HealthDay News) -- A new nomogram has excellent discriminatory ability and accuracy in predicting 10-year disease-specific death and recurrence for papillary thyroid carcinoma (PTC), according to a study published online Sept. 2 in Head & Neck.

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FDA Approves Two New Medications for Diabetes

MONDAY, Sept. 28, 2015 (HealthDay News) -- Two new diabetes treatments, Tresiba (insulin degludec injection) and Ryzodeg (insulin degludec/insulin aspart injection), have been approved by the U.S. Food and Drug Administration.

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Fidgeting Offers Health Benefits to Sedentary Women

FRIDAY, Sept. 25, 2015 (HealthDay News) -- Women who sit for long periods of time but are either moderately or very fidgety have a mortality risk similar to that seen in more active women, according to research published online Sept. 23 in the American Journal of Preventive Medicine.

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Sleep-Time Ambulatory BP Predicts New-Onset Diabetes

THURSDAY, Sept. 24, 2015 (HealthDay News) -- Sleep-time ambulatory blood pressure (ABP) predicts new-onset diabetes, and ingestion of hypertension medications at bedtime is associated with reduced risk of new-onset diabetes, according to two studies published online Sept. 23 in Diabetologia.

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Fewer Multiple Embryos With Femara in Unexplained Infertility

THURSDAY, Sept. 24, 2015 (HealthDay News) -- Use of letrozole (Femara) may reduce a couple's risk of having a pregnancy with multiple embryos -- but it might also slightly lower their chances of a live birth, a new clinical trial suggests. The study was published in the Sept. 24 issue of the New England Journal of Medicine.

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Saxagliptin Not Linked to Increased Fracture Risk in T2DM

THURSDAY, Sept. 24, 2015 (HealthDay News) -- For patients with type 2 diabetes, treatment with saxagliptin is not associated with increased fracture risk, according to a study published online Sept. 10 in Diabetes Care.

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Review Links Obesity to Increased Thyroid Cancer Risk

WEDNESDAY, Sept. 23, 2015 (HealthDay News) -- Obesity is associated with increased risk of thyroid cancer, according to a review published online Sept. 14 in Obesity Reviews.

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Not All Trans Fats Appear to Be Created Equal for Heart Risk

WEDNESDAY, Sept. 23, 2015 (HealthDay News) -- A new study suggests that not all trans fats are equal, and some might even be beneficial. The findings were published online Sept. 22 in the European Heart Journal.

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Health Insurance Deductibles Rising Faster Than Wages

WEDNESDAY, Sept. 23, 2015 (HealthDay News) -- Health insurance deductibles have risen more than six times faster than American workers' average wages since 2010, a Kaiser Family Foundation report says.

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Mediterranean Diet May Protect Against Diabetic Retinopathy

WEDNESDAY, Sept. 23, 2015 (HealthDay News) -- The Mediterranean diet (MedDiet) may protect against diabetic retinopathy, according to a study published online Sept. 13 in Diabetes Care.

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IOM: Most U.S. Patients Will Experience Diagnostic Error

WEDNESDAY, Sept. 23, 2015 (HealthDay News) -- A new report commissioned by the U.S. government contends that most Americans will encounter at least one diagnostic error in their lifetime, sometimes with severe consequences for their physical and mental health.

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Medical Schools Teaching Students About Costs of Care

TUESDAY, Sept. 22, 2015 (HealthDay News) -- Many medical schools are integrating discussions of cost, value, and effectiveness into their curricula, according to Kaiser Health News.

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T2DM Risk With Weight Gain Higher in Younger Adults

TUESDAY, Sept. 22, 2015 (HealthDay News) -- The risk of developing diabetes is higher in younger adults versus middle-aged adults despite the same duration and degree of weight gain, according to research published online Sept. 10 in Diabetes Care.

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More Than 30 Percent of Adults Are Obese in the United States

TUESDAY, Sept. 22, 2015 (HealthDay News) -- In 2014, obesity rates increased in Kansas, Minnesota, New Mexico, Ohio, and Utah, according to a report released Monday from the Trust for America's Health and the Robert Wood Johnson Foundation.

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Docs in Productivity Models Likely to Encounter Compensation Caps

MONDAY, Sept. 21, 2015 (HealthDay News) -- Physicians, especially those working in a productivity model, need to understand compensation caps, which are set at a specific percentile of national pay based on surveys, according to a report in Medical Economics.

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Dextromethorphan + Sitagliptin Promising in Type 2 Diabetes

MONDAY, Sept. 21, 2015 (HealthDay News) -- Dextromethorphan combined with sitagliptin shows potential for treatment of type 2 diabetes mellitus, according to a study published online Sept. 12 in Diabetes, Obesity and Metabolism.

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Cholecalciferol May Help Reduce BMD Loss After Bariatric Surgery

MONDAY, Sept. 21, 2015 (HealthDay News) -- An intervention including cholecalciferol, protein supplementation, and physical exercise reduces bone mineral density loss after bariatric surgery, according to a study published online Sept. 9 in the Journal of Bone and Mineral Research.

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Volunteer Doctors Need to Check Liability Coverage

FRIDAY, Sept. 18, 2015 (HealthDay News) -- Physicians who volunteer their medical expertise should consider their legal risks, according to an article published online Sept. 3 in Medical Economics.

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2012 Office Visits 57% Higher for Women than Men, Ages 1864

FRIDAY, Sept. 18, 2015 (HealthDay News) -- In 2012 there were an estimated 301 physician office visits per 100 persons, with higher rates for females and adults aged 65 years and older, according to a September data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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Mid-Morning May Be Best Time for Workday Break

FRIDAY, Sept. 18, 2015 (HealthDay News) -- Choosing preferred activities for a work break and taking a break earlier in the shift are linked to more resource recovery after a break, according to a study published online Aug. 10 in the Journal of Applied Psychology.

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Type 1 Diabetes in Childhood May Up Atopic Dermatitis Risk

FRIDAY, Sept. 18, 2015 (HealthDay News) -- Type 1 diabetes mellitus (T1DM) in childhood is associated with increased risk of atopic dermatitis (AD), according to a study published online Sept. 15 in the British Journal of Dermatology.

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Positive Results for Home Use of Closed-Loop Insulin System

THURSDAY, Sept. 17, 2015 (HealthDay News) -- A closed-loop insulin delivery system can improve glucose control and reduce hypoglycemia in patients with type 1 diabetes, compared with sensor-augmented pump therapy, according to a study published online Sept. 17 in the New England Journal of Medicine to coincide with presentation at the annual meeting of the European Association for the Study of Diabetes in Stockholm, Sweden.

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Nonperfusion on UWF Imaging Predicts Retinopathy Severity

THURSDAY, Sept. 17, 2015 (HealthDay News) -- Ultrawide-field (UWF) retinal imaging can identify areas of nonperfusion, which are associated with predominantly peripheral lesions (PPLS) in the retina and severity of diabetic retinopathy, according to a study published online Sept. 6 in Ophthalmology.

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'Epidemic of Diagnosis' in Thyroid Cancer

THURSDAY, Sept. 17, 2015 (HealthDay News) -- Advanced imaging technology has increased diagnosis rates of thyroid cancer over the past decade; however, nearly one-third of these cases involve people with low-risk tumors, according to a Mayo Clinic study published in the September issue of Thyroid.

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Addition of Orlistat Benefits Obese Patients With T2DM

THURSDAY, Sept. 17, 2015 (HealthDay News) -- In overweight and obese patients with type 2 diabetes (T2D), treatment with orlistat in addition to lifestyle modifications improves outcomes, according to research published online Sept. 8 in Obesity Reviews.

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Metabolic Syndrome Common in Young Women With Lupus

THURSDAY, Sept. 17, 2015 (HealthDay News) -- Metabolic syndrome is common in young, premenopausal women with systemic lupus erythematosus (SLE), and chloroquine appears to protect against metabolic syndrome in these women, according to a study published online Aug. 26 in Arthritis Care & Research.

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Complex Chronic Diseases Appear to Drive Frequent Admissions

WEDNESDAY, Sept. 16, 2015 (HealthDay News) -- Patients who are frequently admitted to U.S. academic medical centers are significantly more likely than other patients to have multiple complex chronic conditions, according to a study published in the September issue of the Journal of Hospital Medicine.

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Women Less Likely to Be Full Professors Than Men

WEDNESDAY, Sept. 16, 2015 (HealthDay News) -- In academic medicine, women are less likely to be full professors than men and have less startup funding than men, according to two studies published in the Sept. 15 issue of JAMA.

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CDC Develops State-Level Chronic Disease Cost Calculator

TUESDAY, Sept. 15, 2015 (HealthDay News) -- A chronic disease cost calculator (CDCC) has been developed to estimate state-level costs, according to a study published online Sept. 3 in Preventing Chronic Disease.

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Low Vitamin D Status Linked to Accelerated Cognitive Decline

MONDAY, Sept. 14, 2015 (HealthDay News) -- For ethnically diverse older adults, low vitamin D status is associated with accelerated decline in cognitive function, according to a study published online Sept. 14 in JAMA Neurology.

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Leptin Suppresses the Rewarding Effects of Running

FRIDAY, Sept. 11, 2015 (HealthDay News) -- Leptin appears to inhibit running reward via signal transducer and activator of transcription-3 (STAT3), according to an experimental study published online Sept. 1 in Cell Metabolism.

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For Pharma Reps, Access to Physicians Continuing to Drop

FRIDAY, Sept. 11, 2015 (HealthDay News) -- Physician access for pharmaceutical representatives is continuing to decline, with access restricted to some degree for more than half of physicians, according to an AccessMonitor survey published by ZS.

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Gaining Weight in Adulthood Linked to Lower Fecundity

FRIDAY, Sept. 11, 2015 (HealthDay News) -- Body mass index (BMI) at age 18 years, weight change since age 18, and weight in adulthood correlate with fecundity, according to a study published online Sept. 8 in Obstetrics & Gynecology.

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Delayed Diabetic Retinopathy Screening May Be OK in T1DM

FRIDAY, Sept. 11, 2015 (HealthDay News) -- Most children with type 1 diabetes don't need a yearly exam for diabetic retinopathy until age 15, or five years after their diabetes diagnosis, according to research published online Aug. 31 in Ophthalmology.

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Short, Intense Workouts Offer CV Benefits for T2DM Patients

THURSDAY, Sept. 10, 2015 (HealthDay News) -- New research suggests that short bouts of high-intensity exercise could help reverse some early cardiac structure and function changes in patients with type 2 diabetes. The findings were published online Sept. 9 in Diabetologia.

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Modest Predictive Power for HbA1c in Atherosclerotic CVD Risk

THURSDAY, Sept. 10, 2015 (HealthDay News) -- In the context of conventional cardiovascular disease (CVD) risk factors, hemoglobin A1c (HbA1c) has a modest effect on predicted atherosclerotic CVD risk, according to a study published online Sept. 8 in Circulation: Cardiovascular Quality and Outcomes.

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4% Increase in Population of Actively Licensed Physicians

THURSDAY, Sept. 10, 2015 (HealthDay News) -- The total population of actively licensed physicians in the United States and the District of Columbia has increased by 4 percent since 2012, according to a report published in the Journal of Medical Regulation.

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Physician Re-Entry Program Set to Redress Physician Shortage

THURSDAY, Sept. 10, 2015 (HealthDay News) -- An online educational program aims to help physicians get back to work and reduce the nation's physician shortage, according to an article published by the American Academy of Family Physicians (AAFP).

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Management, Treatment of Chronic Disease Up With ACA

WEDNESDAY, Sept. 9, 2015 (HealthDay News) -- More Americans are getting health insurance as a result of the Affordable Care Act, which may lead to many more people getting diagnosed and treated for chronic conditions, such as diabetes, a new study contends. The findings were published in the September issue of Health Affairs.

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Accelerated MD Program Doesn't Mar Academic Performance

WEDNESDAY, Sept. 9, 2015 (HealthDay News) -- An accelerated baccalaureate (BA)/doctor of medicine (MD) program does not impair the academic performance of medical students, according to a study published online July 3 in Academic Medicine.

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Over Half of U.S. Adults Have Diabetes or Prediabetes

WEDNESDAY, Sept. 9, 2015 (HealthDay News) -- More than half of all American adults have type 2 diabetes or prediabetes, according to a new report published in the Sept. 8 issue of the Journal of the American Medical Association.

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ACP Supports Expanded Role of Telemedicine for Health Care

WEDNESDAY, Sept. 9, 2015 (HealthDay News) -- Telemedicine can be beneficial, within the framework of an established physician-patient relationship, according to a position paper published online Sept. 8 in the Annals of Internal Medicine.

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EHR Vendors Not Adhering to Usability Certification Standards

WEDNESDAY, Sept. 9, 2015 (HealthDay News) -- Among electronic health record (EHR) products, there is a lack of adherence to the U.S. Department of Health and Human Services' Office of the National Coordinator for Health Information Technology (ONC) standards, according to a research letter published in the Sept. 8 issue of the Journal of the American Medical Association.

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Metformin Linked to Lower Risk of Head, Neck Cancer

TUESDAY, Sept. 8, 2015 (HealthDay News) -- Metformin is associated with a lower risk of developing head and neck cancer in patients with diabetes, according to a study published in the September issue of Head & Neck.

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TXNIP May Mediate Insulin Sensitivity in Caloric Restriction

TUESDAY, Sept. 8, 2015 (HealthDay News) -- Caloric restriction (CR) improves peripheral insulin sensitivity, possibly by lowering insulin-stimulated thioredoxin-interacting protein (TXNIP) levels and enhancing non-oxidative glucose disposal, according to a study published online Aug. 31 in Diabetes.

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Sleep Affects HOMA-IR in Overweight, Obese Teens

TUESDAY, Sept. 8, 2015 (HealthDay News) -- Overweight and obese adolescents have persistently higher homeostasis model assessment of insulin resistance (HOMA-IR), with significant contributors including total sleep time and sleep efficiency, according to research published in a supplement to the September issue of Diabetes, Obesity and Metabolism.

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Bariatric Surgery Beats Drug Tx for Metabolic Outcomes in T2DM

FRIDAY, Sept. 4, 2015 (HealthDay News) -- Regardless of weight loss, patients with type 2 diabetes who undergo bariatric surgery have better metabolic outcomes than patients treated with drug therapy, according to a study published in the Sept. 5 issue of The Lancet.

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PCOS Linked to Increased Risk of Preterm Delivery for Twins

FRIDAY, Sept. 4, 2015 (HealthDay News) -- Polycystic ovary syndrome (PCOS) diagnosis is associated with increased risk of preterm delivery in twin pregnancies, according to a study published in the September issue of BJOG: An International Journal of Obstetrics and Gynaecology.

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Suggested Response Provided for In-Flight Medical Emergencies

FRIDAY, Sept. 4, 2015 (HealthDay News) -- In a review article published online Sept. 3 in the New England Journal of Medicine, guidance is offered for physicians providing emergency in-flight medical care.

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Type 2 Diabetes Linked to More Alzheimer's Neuropathology

THURSDAY, Sept. 3, 2015 (HealthDay News) -- Individuals with type 2 diabetes mellitus (T2DM) may be more prone to developing the neuropathology associated with Alzheimer's disease, according to a study published online Sept. 2 in Neurology.

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Modest Relation Between HbA1c, Cardiovascular Events

THURSDAY, Sept. 3, 2015 (HealthDay News) -- For patients with type 2 diabetes, hemoglobin A1c (HbA1c) is not significantly associated with cardiovascular events, regardless of clinical manifestation of vascular disease, according to a study published online Aug. 25 in Diabetes Care.

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Sugary Beverage Intake Linked to Triglycerides in Children

THURSDAY, Sept. 3, 2015 (HealthDay News) -- Consumption of sugar-sweetened beverages (SSBs) by children is positively associated with triglyceride concentration, according to a study published online Sept. 2 in the Journal of Nutrition.

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Addition of Glitazone to Chemo May Help Treat CML

THURSDAY, Sept. 3, 2015 (HealthDay News) -- Patients with chronic myeloid leukemia who received a glitazone along with imatinib remained disease-free for up to nearly five years in a study published online Sept. 2 in Nature.

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Finerenone Linked to Improved UACR in Diabetic Nephropathy

WEDNESDAY, Sept. 2, 2015 (HealthDay News) -- For patients with diabetic nephropathy receiving an angiotensin-converting enzyme inhibitor or angiotensin receptor blocker, the addition of finerenone results in improvement in the urinary albumin-creatinine ratio (UACR), according to a study published in the Sept. 1 issue of the Journal of the American Medical Association.

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Many Teens With Chronic Illnesses Use Alcohol, Marijuana

WEDNESDAY, Sept. 2, 2015 (HealthDay News) -- Many adolescents with chronic diseases such as asthma and juvenile arthritis have consumed alcohol or smoked marijuana in the last year, according to a study published online Aug. 31 in Pediatrics.

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CDC: Smoking Rate Falls to 15.2 Percent in the United States

TUESDAY, Sept. 1, 2015 (HealthDay News) -- The U.S. smoking rate continues to decline, with 15.2 percent of adults reporting they're current smokers, down from 16.8 percent in 2014 and 17.8 percent in 2013, the U.S. Centers for Disease Control and Prevention reported Tuesday.

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