Salmeterol + Fluticasone Deemed Safe for Childhood Asthma

Share this content:
Salmeterol + Fluticasone Deemed Safe for Childhood Asthma
Salmeterol + Fluticasone Deemed Safe for Childhood Asthma

THURSDAY, Sept. 1, 2016 (HealthDay News) -- Children using a combination long-acting beta agonist/steroid inhaler do not have any greater risk of harm than children using a steroid inhaler alone, according to a study published in the Sept. 1 issue of the New England Journal of Medicine.

Stanley Szefler, M.D., director of pediatric asthma research for the University of Colorado School of Medicine in Aurora, and colleagues recruited 6,208 children between 4 and 11 years old. They were randomly assigned inhalers containing a combination of salmeterol and fluticasone, or fluticasone alone.

Of all the patients, 27 in the combination drug group had a serious asthma-related event that required hospitalization, compared with 21 in the steroid-only group. There were no deaths, and no emergencies that required endotracheal intubation.

"The next step is for the FDA to assemble all the available studies, make their own interpretation, and determine how that would affect product labeling," Szefler told HealthDay.

Several authors disclosed financial ties to pharmaceutical companies, including GlaxoSmithKline, which manufactures Advair (fluticasone/salmeterol) and funded the study.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

FDA Approves Bavencio for Merkel Cell Carcinoma

FDA Approves Bavencio for Merkel Cell Carcinoma

Drug targets the PD-1/PD-L1 pathway; first sanctioned treatment in the United States

Heterogeneous Association for Alcohol, CVD Presentation

Heterogeneous Association for Alcohol, CVD Presentation

Non-drinking linked to increased risks of unstable angina, MI, heart failure, ischemic stroke, PAD, AAA

Mobile App Cuts In-Person Visits After Breast Reconstruction

Mobile App Cuts In-Person Visits After Breast Reconstruction

Number of visits down, increase in e-mails to doctors for ambulatory patients undergoing breast recon

is free, fast, and customized just for you!

Already a member?

Sign In Now »