Saline-Based Nasal Spray Found to Be Effective for Epistaxis

This article originally appeared here.
Share this content:
Saline-Based Nasal Spray Found to Be Effective for Epistaxis
Saline-Based Nasal Spray Found to Be Effective for Epistaxis

WEDNESDAY, Sept. 7, 2016 (HealthDay News) -- A simple saline-based nasal spray is as effective as medicated sprays in controlling epistaxis in patients with hereditary hemorrhagic telangiectasia (HHT), according to a study published in the Sept. 6 issue of the Journal of the American Medical Association.

The new study included 121 patients meeting the clinical criteria for HHT who sprayed either a saline solution or one of three medications -- bevacizumab, estriol, or tranexamic acid -- into their nose twice a day for 12 weeks.

The researchers found that the saline spray was as effective in reducing epistaxis as the drugs. "No drug proved to be any better than the saline placebo, but the majority of patients improved over the course of treatment -- even those using saline," study author Kevin Whitehead, M.D., an associate professor of internal medicine at the University of Utah School of Medicine in Salt Lake City, said in a university news release. "This research highlights that there could be a benefit even in the simplest of interventions."

HHT-related epistaxis is slightly different from common epistaxis. The use of saline spray for common epistaxis hasn't been assessed, but would be easy to test, the researchers noted.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease


More in Home

ASTRO: No Survival Benefit for Adding EBT to Brachytherapy

ASTRO: No Survival Benefit for Adding EBT to ...

Addition of external beam therapy doesn't improve five-year progression-free survival in prostate cancer

ASTRO: Fewer Side Effects With IMRT in Cervical, Endometrial CA

ASTRO: Fewer Side Effects With IMRT in Cervical, ...

Patients in conventional radiotherapy arm had more high-level adverse events than those in IMRT arm

Many Doctors Reluctant to Reveal Mental Health Issues

Many Doctors Reluctant to Reveal Mental Health Issues

Perceived stigma, fear of career repercussions hinder treatment, study suggests

is free, fast, and customized just for you!

Already a member?

Sign In Now »