SABCS: Aromatase Inhibitors Tied to Reduced Endothelial Function

Share this content:
SABCS: Aromatase Inhibitors Tied to Reduced Endothelial Function
SABCS: Aromatase Inhibitors Tied to Reduced Endothelial Function

FRIDAY, Dec. 9, 2016 (HealthDay News) -- Women taking aromatase inhibitors may show signs of early endothelial dysfunction that could lead to cardiovascular disease, according to a study presented at the annual San Antonio Breast Cancer Symposium, held from Dec. 6 to 10 in Texas.

The results are based on 36 postmenopausal women with early-stage breast cancer who were prescribed an aromatase inhibitor. For comparison, the researchers looked at 25 healthy women the same age. The researchers performed biomarker analysis and pulse wave analysis to gauge several components of endothelial function.

Overall, the investigators found, women on aromatase inhibitors showed less elasticity in their blood vessels, and scored significantly lower on the EndoPAT ratio measure (0.8 in the breast cancer survivors who took aromatase inhibitors and 2.7 in the controls).

Lead researcher Anne Blaes, M.D., of the University of Minnesota in Minneapolis, pointed to the importance of a healthy diet and regular exercise. "Often, women were not physically active before their breast cancer diagnosis, and that continues afterward," Blaes told HealthDay. "My advice is, try to find ways to keep moving."

Press Release
More Information

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Approves Zejula for Certain Female Cancers

FDA Approves Zejula for Certain Female Cancers

PARP inhibitor may help fight tumors affecting the ovaries, fallopian tubes, or peritoneum

USPSTF: Evidence Lacking for Celiac Dz Screen in Asymptomatic

USPSTF: Evidence Lacking for Celiac Dz Screen in ...

Insufficient evidence for weighing benefits, harms of screening for celiac disease in asymptomatic

Lap, Abdominal Hysterectomy Equal for Early Endometrial CA

Lap, Abdominal Hysterectomy Equal for Early Endometrial CA

Equivalent disease-free survival at 4.5 years for stage I endometrial cancer with TAH, TLH

is free, fast, and customized just for you!

Already a member?

Sign In Now »