RT Dose Main Risk for Radiation-Induced Optic Neuropathy

Share this content:
RT Dose Main Risk for Radiation-Induced Optic Neuropathy
RT Dose Main Risk for Radiation-Induced Optic Neuropathy

MONDAY, Feb. 13, 2017 (HealthDay News) -- The main risk factor for developing radiation-induced optic neuropathy (RION) is radiation dose, with no indication of other significant risk factors, according to a study published online Feb. 9 in Clinical & Experimental Ophthalmology.

Ian Ferguson, from Washington University in St. Louis, and colleagues conducted a retrospective case-control study at a university hospital tertiary care center. They identified 14 cases meeting criteria for a diagnosis of RION by neuro-ophthalmologic exam. Cases were matched with 31 controls without RION based upon maximum radiation dose to the optic apparatus. The authors examined patient characteristics and treatment parameters for attributes predisposing to RION in univariate analysis.

The researchers found that there were no significant associations for alternative risk factors after controlling for radiation dosage.

"These results support the literature suggesting that the primary risk factor for developing RION is radiation dosage and that additional, patient- and tumor-related risk factors may play only a minor role," the authors write.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

Recent Decline in Prescription Opioid Use Among U.S. Teens

Recent Decline in Prescription Opioid Use Among U.S. ...

Lifetime prevalence of use peaked in 1989, 2002, and remained stable until decline in 2013 to 2015

Treatment Seeking Low Among Teens With Eating Disorders

Treatment Seeking Low Among Teens With Eating Disorders

Those with counter-stereotypic presentation even less likely to seek treatment

Optical Clearing Agent Ups No. of Laser Passes in Tattoo Removal

Optical Clearing Agent Ups No. of Laser Passes ...

Findings based on number of laser passes during a five-minute tattoo removal session

is free, fast, and customized just for you!

Already a member?

Sign In Now »