Review Provides Evidence for Sweet Taste Analgesia in Infants

Share this content:
Review Provides Evidence for Sweet Taste Analgesia in Infants
Review Provides Evidence for Sweet Taste Analgesia in Infants

FRIDAY, Dec. 16, 2016 (HealthDay News) -- Despite evidence for sweet taste reducing pain and crying time in neonates, most trials still include placebo/no-treatment arms, according to a review published online Dec. 16 in Pediatrics.

Denise Harrison, R.N., Ph.D., from the Children's Hospital of Eastern Ontario in Ottawa, Canada, and colleagues conducted a systematic review of all trials evaluating sweet solutions for analgesia in neonates and conducted cumulative meta-analyses (CMAs) on behavioral pain outcomes. Data were included for 168 studies; 88 percent included placebo/no-treatment arms.

The researchers found that the CMA for crying time included 29 trials with 1,175 infants. There was a statistically significant reduction in mean cry time for sweet solutions versus placebo from the fifth trial in 2002 (−27 seconds). CMA was −23 seconds in favor of sweet solutions by the final trial. For pain scores, CMA included 50 trials with 3,341 infants. From the second trial the results were in favor of sweet solutions. A standardized mean difference of −0.9 was seen in the final results.

"Evidence of sweet taste analgesia in neonates has existed since the first published trials, yet placebo/no-treatment, controlled trials have continued to be conducted," the authors write. "Future neonatal pain studies need to select more ethically responsible control groups."

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions


Sign up for myCME e-newsletters


More in Home

Structural Findings of Acute Solar Retinopathy Described

Structural Findings of Acute Solar Retinopathy Described

Patient in case study presented three days after viewing solar eclipse

Telomere Fusions Predict Dysplasia, Invasive Pancreatic CA

Telomere Fusions Predict Dysplasia, Invasive Pancreatic CA

Telomere fusions are detected in later stages of intraductal papillary mucinous neoplasm progression

Prenatal Sugar Intake May Increase Asthma Risk in Offspring

Prenatal Sugar Intake May Increase Asthma Risk in ...

Higher intake during pregnancy, in early childhood associated with childhood asthma development

is free, fast, and customized just for you!

Already a member?

Sign In Now »