Resveratrol Doesn't Improve Insulin Sensitivity

Share this content:
Resveratrol Doesn't Improve Insulin Sensitivity
Resveratrol Doesn't Improve Insulin Sensitivity

MONDAY, Oct. 24, 2016 (HealthDay News) -- Resveratrol supplementation does not improve hepatic or peripheral insulin sensitivity among patients with type 2 diabetes, according to a study published online Oct. 7 in Diabetes Care.

Silvie Timmers, Ph.D., from Maastricht University in the Netherlands, and colleagues treated 17 subjects with well-controlled type 2 diabetes with placebo and 150 mg/day resveratrol in a randomized double-blind crossover study for 30 days.

The researchers found that hepatic and peripheral insulin sensitivity were not affected by resveratrol treatment. Resveratrol similarly did not affect intrahepatic lipid content, although the change in intrahepatic lipid content correlated negatively with plasma resveratrol levels. Resveratrol was also found to significantly improve ex vivo mitochondrial function.

"Our results question the generalized value of resveratrol as add-on therapy in the treatment of type 2 diabetes and emphasize the need to perform studies in drug-naive patients with type 2 diabetes or subjects with prediabetes," the authors write.

One author was employed by DSM Nutritional Products, which supplied the resveratrol and placebo capsules and performed the resveratrol and dihydroresveratrol analysis.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

NTproBNP Levels Are Significantly Lower in Blacks

NTproBNP Levels Are Significantly Lower in Blacks

Higher NTproBNP levels linked to increased risk of death; this association did not differ by race

Data May Weigh on Pros/Cons of Expanded Care Optometry

Data May Weigh on Pros/Cons of Expanded Care ...

Majority of residents in Kentucky, Oklahoma, New Mexico live within 30 minutes of ophthalmologist

Gaps Seen Between Hearing Loss, Receipt of Medical Evaluation, Tx

Gaps Seen Between Hearing Loss, Receipt of Medical ...

About 20.6 percent of those with hearing less than excellent/good had visited doctor for hearing issues

is free, fast, and customized just for you!

Already a member?

Sign In Now »