Renal Function Tests Stratify Risk in Pregnant Women With HTN

Share this content:
Renal Function Tests Stratify Risk in Pregnant Women With HTN
Renal Function Tests Stratify Risk in Pregnant Women With HTN

THURSDAY, June 9, 2016 (HealthDay News) -- Baseline renal function tests can stratify the risk of severe preeclampsia in pregnant women with chronic hypertension, according to a study published in the July issue of Obstetrics & Gynecology.

Spencer G. Kuper, M.D., from the University of Alabama at Birmingham, and colleagues examined the correlation between baseline renal function tests and adverse pregnancy outcomes in a cohort of women with a singleton pregnancy and chronic hypertension. Baseline renal function assessment data were available for 755 pregnant women with chronic hypertension.

The researchers found that for urine protein-to-creatinine ratio and for creatinine, the area under the receiver operating characteristic curves for severe preeclampsia was 0.74 and 0.67, respectively. The risk of developing severe preeclampsia at less than 34 weeks of gestation was increased with a urine protein-to-creatinine ratio of 0.12 or greater (16.4 versus 2.6 percent; adjusted odds ratio, 7.5) and with creatinine of 0.75 mg/dL or greater (15.7 versus 4.6 percent; adjusted odds ratio, 3.5). For those with both baseline tests below cut-off, only 1.6 percent had severe preeclampsia at less than 34 weeks of gestation.

"Baseline assessment of renal function can be used as a risk stratification tool in pregnant patients with chronic hypertension," the authors write.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

High Costs Associated With Physician Burnout, Attrition

High Costs Associated With Physician Burnout, Attrition

Economic loss at Stanford over two years expected to range from $15.5 million to $55.5 million

Insulin Doesn't Prevent Diabetes in Relatives of T1DM Patients

Insulin Doesn't Prevent Diabetes in Relatives of T1DM ...

Oral insulin doesn't delay onset in autoantibody-positive relatives of patients with type 1 diabetes

Workplace Sexual Harassment Ongoing in Women, Up for Men

Workplace Sexual Harassment Ongoing in Women, Up for ...

Women report more adverse effects after SH than men, but SH can trigger depression, anxiety in men

is free, fast, and customized just for you!

Already a member?

Sign In Now »