Recommendations Updated for Use of Antiretroviral Tx in HIV

This article originally appeared here.
Share this content:
Recommendations Updated for Use of Antiretroviral Tx in HIV
Recommendations Updated for Use of Antiretroviral Tx in HIV

WEDNESDAY, July 13, 2016 (HealthDay News) -- Recommendations for the use of antiretroviral therapy in HIV infection have been updated for adults, and published in the July 12 issue of the Journal of the American Medical Association, a theme issue on HIV/AIDS.

Huldrych F. Günthard, M.D., from the University Hospital Zurich, and colleagues updated recommendations for the use of antiretroviral therapy in adults with established HIV infection. A panel of experts in HIV research and patient care reviewed data and conducted comprehensive literature searches to develop recommendations.

The researchers note that newer data support the widely accepted recommendation that all individuals with HIV infection with detectable viremia should start antiretroviral therapy, regardless of CD4 cell count. For most patients, recommended optimal initial regimens are two nucleoside reverse transcriptase inhibitors (NRTIs) plus an integrase strand transfer inhibitor. Non-NRTIs or boosted protease inhibitors with two NRTIs are also effective regimens. Convenience, tolerability, simplification, anticipation of potential new drug interactions, and pregnancy or plans for pregnancy are included as reasons for switching therapy. In persons at high risk, daily tenofovir disoproxil fumarate/emtricitabine is recommended for use as preexposure prophylaxis to prevent HIV infection; postexposure prophylaxis should be started as soon as possible after exposure, when indicated.

"Antiretroviral agents remain the cornerstone of HIV treatment and prevention," the authors write. "With these treatment regimens, survival rates among HIV-infected adults who are retained in care can approach those of uninfected adults."

Several authors disclosed financial ties to the pharmaceutical industry.

Abstract
Full Text
Editorial

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

NTproBNP Levels Are Significantly Lower in Blacks

NTproBNP Levels Are Significantly Lower in Blacks

Higher NTproBNP levels linked to increased risk of death; this association did not differ by race

Data May Weigh on Pros/Cons of Expanded Care Optometry

Data May Weigh on Pros/Cons of Expanded Care ...

Majority of residents in Kentucky, Oklahoma, New Mexico live within 30 minutes of ophthalmologist

Gaps Seen Between Hearing Loss, Receipt of Medical Evaluation, Tx

Gaps Seen Between Hearing Loss, Receipt of Medical ...

About 20.6 percent of those with hearing less than excellent/good had visited doctor for hearing issues

is free, fast, and customized just for you!

Already a member?

Sign In Now »