Recommendations Updated for H. pylori Treatment in Adults

This article originally appeared here.
Share this content:
Recommendations Updated for <i>H. pylori</i> Treatment in Adults
Recommendations Updated for H. pylori Treatment in Adults

TUESDAY, July 12, 2016 (HealthDay News) -- Recommendations have been updated for treatment of Helicobacter pylori in adults, according to a consensus statement published in the July issue of Gastroenterology.

Carlo A. Fallone, M.D., from the McGill University Health Centre in Montreal, and colleagues conducted a systematic literature review and developed specific, updated recommendations for eradication therapy in adults with H. pylori infection.

The researchers strongly recommend that all H. pylori regimens should be given for 14 days because of the increasing failure of therapy. Concomitant nonbismuth quadruple therapy (proton pump inhibitor [PPI] + amoxicillin + metronidazole + clarithromycin [PAMC]) and traditional bismuth quadruple therapy (PPI + bismuth + metronidazole + tetracycline [PBMT]) were included as recommended first-line strategies. Use of PPI triple therapy (PPI + clarithromycin + amoxicillin or metronidazole) should be limited to regions with low resistance to clarithromycin or high eradication success with these regimens. PBMT and levofloxacin-containing therapy were included as recommended rescue therapies. Rifabutin therapy should be used only for patients who have failed to respond to three or more previous treatment regimens.

"Optimal treatment of H. pylori infection requires careful attention to local antibiotic resistance and eradication patterns," the authors write. "The quadruple therapies PAMC or PBMT should play a more prominent role in eradication of H. pylori infection, and all treatments should be given for 14 days."

Several authors disclosed financial ties to the pharmaceutical industry.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

ASCO: Moderate Activity Tied to Longer Survival in Advanced CRC

ASCO: Moderate Activity Tied to Longer Survival in ...

Patients only appeared to derive benefit from moderate -- not vigorous -- activity

Number of Infants Born to Women Using Opioids Up Sharply

Number of Infants Born to Women Using Opioids ...

Few treatment programs deal with substance abuse in expectant moms, federal report says

Hypertension Onset After Age 80 May Protect Against Dementia

Hypertension Onset After Age 80 May Protect Against ...

Association independent of antihypertensive medication use

is free, fast, and customized just for you!

Already a member?

Sign In Now »