Ratio of ω-6:ω-3 Fatty Acids Implicated in Obesity

Share this content:
Ratio of ω-6:ω-3 Fatty Acids Implicated in Obesity
Ratio of ω-6:ω-3 Fatty Acids Implicated in Obesity

WEDNESDAY, Oct. 26, 2016 (HealthDay News) -- Governments and international organizations should focus on redressing the balance of ω-6 and ω-3 fatty acids in order to address obesity, according to an editorial published in the September issue of Open Heart.

Artemis P. Simopoulos, M.D., from The Center for Genetics, Nutrition, and Health in Washington, D.C., and James J. DiNicolantonio, Pharm.D., from Saint Luke's Mid America Heart Institute in Kansas, Mo., discuss the inability of countries to prevent overweight and obesity or maintain weight loss of their populations.

The researchers note that scientific evidence has demonstrated that calories are not equivalent, with calories from ω-6 fatty acids proinflammatory and thrombogenic, whereas calories from ω-3 fatty acids are anti-inflammatory and antithrombotic. In addition, calories from ω-6 fatty acid intake have distinct effects on fat tissue development and type than calories from ω-3 fatty acids. Traditionally, the amount of ω-6 and ω-3 fatty acids was balanced, but the recent phenomenon of an imbalance (typically 16:1 in a Western diet) leads to increases in white adipose tissue and chronic inflammation. A high ω-6 to ω-3 ratio also correlates with increased risk of weight gain. Genetic differences in the metabolism of fatty acids should also be considered in addressing obesity.

"It is the responsibility of the governments and international organizations to establish nutrition policies based on science and not continue along the same path of focusing exclusively on calories and energy expenditure, which have failed miserably over the past 30 years," the authors write.

Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

ASH: Synthetic Blood Cell Passes Proof-of-Concept Testing

ASH: Synthetic Blood Cell Passes Proof-of-Concept Testing

Synthetic product made from purified human hemoglobin proteins coated with a synthetic polymer

Fewer School Shootings in States With Tighter Gun Laws

Fewer School Shootings in States With Tighter Gun ...

Study also found that states that spent more money on mental health care, education saw less violence

SABCS: No Survival Benefit Seen for Letrozole Beyond Five Years

SABCS: No Survival Benefit Seen for Letrozole Beyond ...

Study found women who continued with letrozole did experience other benefits, however

is free, fast, and customized just for you!

Already a member?

Sign In Now »