Psychosocial Factors Predict Functional Disability in RA

This article originally appeared here.
Share this content:
Psychosocial Factors Predict Functional Disability in RA
Psychosocial Factors Predict Functional Disability in RA

FRIDAY, July 8, 2016 (HealthDay News) -- Psychosocial factors may be more important than traditional clinical measures in predicting functional disability in the first year after a rheumatoid arthritis (RA) diagnosis, according to a study published online June 24 in Arthritis & Rheumatology.

Caroline Kronisch, M.D., from Cantonal Hospital Fribourg in Switzerland, and colleagues used data from a prospective cohort of 578 patients (64.5 percent female) with newly presenting RA or undifferentiated arthritis to determine baseline predictors of disability (defined as a Health Assessment Questionnaire [HAQ] score of ≥1) at one year.

The researchers found that 36.7 percent of patients reported functional disability at one year. Predictors of functional disability at one year were baseline disability (odds ratio [OR], 2.67; 95 percent confidence interval [CI], 1.98 to 3.59), depression (OR, 2.52; 95 percent CI, 1.18 to 5.37), anxiety (OR, 2.37; 95 percent CI, 1.33 to 4.21), being in paid employment with absenteeism during the last week (OR, 1.19; 95 percent CI, 0.63 to 2.23), not being in paid employment (OR, 2.36; 95 percent CI, 1.38 to 4.03), and being overweight (OR, 1.61; 95 percent CI, 1.04 to 2.5).

"In the context of modern early inflammatory arthritis treatment paradigms, predictors of disability at one year appear to be dominated by psychosocial rather than more traditional clinical measures," conclude the authors.

Several authors report financial ties to pharmaceutical companies including Pfizer, which partially funded the study.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters




More in Home

Non-Nutritive Sweeteners Don't Up Blood Glucose Levels

Non-Nutritive Sweeteners Don't Up Blood Glucose Levels

Concentration of NNSs decreases gradually over the course of observation after consumption

Laws Allowing Service Denial to Sexual Minorities Tied to Distress

Laws Allowing Service Denial to Sexual Minorities Tied ...

Laws permitting denial of services linked to increase in mental distress among sexual minorities

Antidepressant Prescribing Linked to Lasting Weight Gain

Antidepressant Prescribing Linked to Lasting Weight Gain

Risk of weight gain remained increased during at least six years of follow-up