Prolonged Detection of Zika RNA Reported in Pregnant Women

Share this content:
Prolonged Detection of Zika RNA Reported in Pregnant Women
Prolonged Detection of Zika RNA Reported in Pregnant Women

THURSDAY, Aug. 4, 2016 (HealthDay News) -- Prolonged detection of Zika virus RNA has been documented in five pregnant women, according to research published online July 29 in Obstetrics & Gynecology.

Dana Meaney-Delman, M.D., M.P.H., from the U.S. Centers for Disease Control and Prevention in Atlanta, and colleagues summarized the clinical and laboratory characteristics of pregnant women with prolonged detection of Zika virus RNA in serum. Data were obtained from the U.S. Zika Pregnancy Registry. Prolonged detection was defined as Zika virus RNA detection in serum by real-time reverse transcription-polymerase chain reaction (RT-PCR) of 14 or more days after symptom onset, or 21 or more days after last possible exposure to Zika virus among asymptomatic women.

The researchers identified prolonged Zika virus RNA detection in serum up to 46 days after symptom onset in four symptomatic pregnant women, and at 53 days post-exposure in one asymptomatic pregnant woman. One of the five pregnancies had evidence of fetal Zika virus infection, which was confirmed by histopathologic examination of fetal tissue; three pregnancies resulted in live births with no reported abnormalities, and one pregnancy was ongoing.

"Zika virus RNA was detected in the serum of five pregnant women beyond the previously estimated timeframe," the authors write. "Additional real-time RT-PCR testing of pregnant women might provide more data about prolonged detection of Zika virus RNA and the possible diagnostic, epidemiologic, and clinical implications for pregnant women."

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

NTproBNP Levels Are Significantly Lower in Blacks

NTproBNP Levels Are Significantly Lower in Blacks

Higher NTproBNP levels linked to increased risk of death; this association did not differ by race

Data May Weigh on Pros/Cons of Expanded Care Optometry

Data May Weigh on Pros/Cons of Expanded Care ...

Majority of residents in Kentucky, Oklahoma, New Mexico live within 30 minutes of ophthalmologist

Gaps Seen Between Hearing Loss, Receipt of Medical Evaluation, Tx

Gaps Seen Between Hearing Loss, Receipt of Medical ...

About 20.6 percent of those with hearing less than excellent/good had visited doctor for hearing issues

is free, fast, and customized just for you!

Already a member?

Sign In Now »