Probiotic Supplements Beneficial in Rheumatoid Arthritis

This article originally appeared here.
Share this content:
Probiotic Supplements Beneficial in Rheumatoid Arthritis
Probiotic Supplements Beneficial in Rheumatoid Arthritis

THURSDAY, May 5, 2016 (HealthDay News) -- Probiotic supplementation seems beneficial for patients with rheumatoid arthritis (RA), according to a study published online May 2 in the International Journal of Rheumatic Diseases.

Batol Zamani, from Kashan University of Medical Sciences in Iran, and colleagues randomized 60 patients (aged 25 to 70 years) with RA in a 1:1 ratio to receive probiotic capsules or placebo for eight weeks. The probiotic capsule contained three viable, freeze-dried strains: Lactobacillus acidophilus, Lactobacillus casei, and Bifidobacterium bifidum. Related markers were quantified in fasting blood samples taken at the beginning and end of the study.

The researchers found that probiotic supplementation correlated with improved Disease Activity Score of 28 joints (DAS-28) compared with placebo (P = 0.01) after eight weeks of intervention. Compared with placebo, probiotic supplementation was also associated with a significant decrease in serum insulin levels (P = 0.03), homeostatic model assessment-B cell function (HOMA-B; P = 0.03), and serum high-sensitivity C-reactive protein (hs-CRP) concentrations (P < 0.001). Borderline statistically significant improvements were seen in total and low-density lipoprotein cholesterol levels with probiotics versus placebo (P = 0.09 and 0.07, respectively).

"Overall, the results of this study indicated that taking probiotic supplements for eight weeks among patients with RA had beneficial effects on DAS-28, insulin levels, HOMA-B, and hs-CRP levels," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease


More in Home

Both Statin, Non-Statin Therapies Effective for Lowering LDL

Both Statin, Non-Statin Therapies Effective for Lowering LDL

Dietary changes, other meds, and even surgery can lower cardiovascular risk similarly to statins

Negative Effects Seen With Video Gaming 9 Hours/Week

Negative Effects Seen With Video Gaming 9&#43; Hours/Week

Benefits seen with one hour a week, but behavioral problems appear to rise at nine hours a week

Improved Adult Lung Function Linked to Childhood Farm Life

Improved Adult Lung Function Linked to Childhood Farm ...

First study to report beneficial effects of growing up on a farm on adult FEV1

is free, fast, and customized just for you!

Already a member?

Sign In Now »