Prenatal n-3 LCPUFAs Don't Cut IgE-Linked Disease in Children

Share this content:
Prenatal n-3 LCPUFAs Don't Cut IgE-Linked Disease in Children
Prenatal n-3 LCPUFAs Don't Cut IgE-Linked Disease in Children

THURSDAY, May 26, 2016 (HealthDay News) -- Prenatal supplementation with omega-3 (n-3) long-chain polyunsaturated fatty acids (LCPUFA) does not reduce immunoglobulin E (IgE)-associated allergic disease in children, according to a study published online May 25 in Pediatrics.

Karen P. Best, R.N., Ph.D., from the South Australian Health and Medical Research Institute in Adelaide, and colleagues assessed 706 children with a family history of allergic disease from the Docosahexaenoic Acid to Optimize Mother Infant Outcome trial at six-year follow-up. Women enrolled in the trial were randomized to n-3 LCPUFA-rich fish oil capsules or vegetable oil capsules.

The researchers found that the percentage of children with any IgE-associated allergic disease did not differ between the n-3 LCPUFA and control groups (31.5 versus 31.5 percent; adjusted relative risk, 1.04; 95 percent confidence interval, 0.82 to 1.33). The percentage of children sensitized to house dust mite Dermatophagoides farinae was reduced in the n-3 LCPUFA group (13.4 versus 20.3 percent; adjusted relative risk, 0.67; 95 percent confidence interval, 0.44 to 1.00).

"Prenatal n-3 LCPUFA supplementation did not reduce IgE-associated allergic disease at 6 years of age," the authors write. "Secondary outcomes were suggestive of a protective effect of the intervention on the incidence of D. farinae sensitization."

Two authors disclosed financial ties to the nutrition industry; one author has a patent pending.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Better Stem Cell Tx Outcomes for Younger MS Patients

Better Stem Cell Tx Outcomes for Younger MS ...

Results support additional trials of autologous hematopoietic stem cell transplantation

OD Risk Up in Children Whose Mothers Are Prescribed Opioids

OD Risk Up in Children Whose Mothers Are ...

Second study finds opioids stored unsafely in many households with children

AAP Urges Doctors Not to Punish Pregnant Women for Opioid Use

AAP Urges Doctors Not to Punish Pregnant Women ...

Group says better prevention and treatment, not jail time, would stem surge in drug-addicted newborns

is free, fast, and customized just for you!

Already a member?

Sign In Now »