Pre-Exposure Prophylaxis for Homosexual Men Cost-Effective

Share this content:
Pre-Exposure Prophylaxis for Homosexual Men Cost-Effective
Pre-Exposure Prophylaxis for Homosexual Men Cost-Effective

WEDNESDAY, Oct. 18, 2017 (HealthDay News) -- Introduction of an HIV pre-exposure prophylaxis (PrEP) program for men who have sex with men (MSM) in the United Kingdom is likely to be cost-effective, according to a study published online Oct. 17 in the The Lancet Infectious Diseases.

Valentina Cambiano, Ph.D., from University College London, and colleagues conducted a modeling study and economic evaluation, calibrating a dynamic, individual-based stochastic model to multiple data sources on HIV among MSM. Analyses were conducted to evaluate introduction of a PrEP program with sexual event-based use of emtricitabine and tenofovir for MSM who had engaged in condomless anal sexual intercourse in the previous three months and were HIV-negative at baseline.

The researchers found that introduction of a PrEP program, with about 4,000 and 40,000 MSM initiated on PrEP by the end of the first year and the 15th year, respectively, would be cost-saving (£1 billion discounted), prevent 25 percent of HIV infections (42 percent directly related to PrEP), and lead to 40,000 discounted quality-adjusted life years gained over an 80-year time horizon. This result was sensitive to the time horizon, the cost of treatment and PrEP antiretroviral drugs, and trends in condomless sex.

"This analysis suggests that the introduction of a PrEP program for MSM in the United Kingdom is cost-effective and possibly cost-saving in the long term," the authors write. "A reduction in the cost of antiretroviral drugs (including the drugs used for PrEP) would substantially shorten the time for cost savings to be realized."

Several authors disclosed ties to the pharmaceutical industry.

Abstract/Full Text
Editorial

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease



Sign up for myCME e-newsletters




More in Home

Some California Mosquitoes Can Carry Zika Virus

Some California Mosquitoes Can Carry Zika Virus

Aedes aegypti mosquitoes found to transmit Zika virus

Periodontal Inflammation a Risk With Tongue Piercing

Periodontal Inflammation a Risk With Tongue Piercing

And, two young females with tongue piercings have deep lingual infrabony lesions, periodontitis

Risk of OD Highest for First Days of Opioid  Benzodiazepine Use

Risk of OD Highest for First Days of ...

Five-fold increased risk of opioid-related overdose during first 90 days of concurrent use

is free, fast, and customized just for you!




Already a member?

Sign In Now »