Postural Instability Predicts Off-Loading Nonadherence in T2DM

Share this content:
Postural Instability Predicts Off-Loading Nonadherence in T2DM
Postural Instability Predicts Off-Loading Nonadherence in T2DM

THURSDAY, June 9, 2016 (HealthDay News) -- For patients with diabetic foot ulcers (DFUs), off-loading adherence is associated with healing, but postural instability is a powerful predictor of nonadherence, according to a study published online June 6 in Diabetes.

Ryan T. Crews, from the Rosalind Franklin University in Chicago, and colleagues conducted a prospective, multicenter study involving 79 patients (46 from the United Kingdom and 33 from the United States) with type 2 diabetes and plantar DFUs. DFUs were offloaded with a removable device, and the correlation between off-loading adherence and healing was assessed over a six-week period.

In multivariate analyses, the researchers found that smaller baseline DFU size, U.K. study site, and better off-loading adherence were predictors of smaller DFU size at six weeks (P < 0.05). Larger and more severe baseline DFUs and more severe neuropathy and Neuropathy and Foot Ulcer Quality of Life (NeuroQoL) foot pain predicted better off-loading adherence (P < 0.05). Worse off-loading adherence was predicted by greater NeuroQoL postural instability (P < 0.001). There was no correlation for the Hospital Anxiety and Depression Scale and Revised Illness Perception Questionnaire with off-loading adherence.

"Clinicians should take this neuropathic symptom into consideration when selecting an off-loading device, as off-loading-induced postural instability may further contribute to nonadherence," the authors write.

One author disclosed financial ties to Össur Americas, which is a manufacturer of off-loading devices.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Clinician Awareness of Exercise Addiction May Be Lacking

Clinician Awareness of Exercise Addiction May Be Lacking

Screening questions should focus on emotional connection to exercise, whether it interferes with life

Overall Vagotomy Not Linked to Risk of Parkinson's Disease

Overall Vagotomy Not Linked to Risk of Parkinson's ...

But there is a trend toward lower risk of Parkinson's for patients with truncal vagotomy

Pediatricians Missing Elevated Blood Lead Levels in U.S.

Pediatricians Missing Elevated Blood Lead Levels in U.S.

In 23 of 39 reporting states, pediatric care providers identified fewer than half of children with EBLL

is free, fast, and customized just for you!

Already a member?

Sign In Now »