Persistent Depression Linked to Increased CAC Scores in Women

This article originally appeared here.
Share this content:
Persistent Depression Linked to Increased CAC Scores in Women
Persistent Depression Linked to Increased CAC Scores in Women

MONDAY, June 13, 2016 (HealthDay News) -- Persistent depressive symptoms are associated with increased coronary artery calcium (CAC) scores among middle-aged women without cardiovascular disease (CVD), according to a study published in the June 15 issue of The American Journal of Cardiology.

Imke Janssen, Ph.D., from the Rush University Medical Center in Chicago, and colleagues assessed participants in the Study of Women's Health Across the Nation Heart study annually for depressive symptoms over five years before CAC assessment.

The researchers found that high depressive symptoms were common over five years in middle-aged women free from CVD and diabetes: 19 percent had one, 9 percent had two, and 11 percent experienced three or more episodes. Overall, CAC was low, with 54, 25, and 21 percent having no CAC, 0 to 10, and ≥10 Agatston units, respectively. Compared to women with no depressive episodes, women with three or more episodes were twice as likely to have significant CAC (≥10 Agatston units), after adjustment for CVD risk factors (odds ratio, 2.20), with no difference by race. There was no difference for women with one or two episodes versus no episodes.

"In healthy women aged 46 to 59 years without clinical CVD or diabetes, persistent depressive symptoms were significantly associated with elevated CAC scores, suggesting that they are more likely to have pathophysiological and behavioral effects on the development of subclinical CVD than does a single episode of elevated depressive symptoms," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

Caffeine Found to Reduce Age-Related Inflammation

Caffeine Found to Reduce Age-Related Inflammation

Connection between advancing age, systemic inflammation, cardiovascular disease and caffeine

Neonatal Abstinence Syndrome Tied to Poor School Performance

Neonatal Abstinence Syndrome Tied to Poor School Performance

By seventh grade, four out of 10 failed to meet standards in at least one academic area

Heart Rate Variability Linked to Atrial Fibrillation

Heart Rate Variability Linked to Atrial Fibrillation

Lower HRV, increased sympathetic/parasympathetic tone linked to higher risk of a-fib

is free, fast, and customized just for you!

Already a member?

Sign In Now »