Peri-Op IV Corticosteroids Benefit Knee, Hip Arthroplasty

This article originally appeared here.
Share this content:
Peri-Op IV Corticosteroids Benefit Knee, Hip Arthroplasty
Peri-Op IV Corticosteroids Benefit Knee, Hip Arthroplasty

THURSDAY, Sept. 14, 2017 (HealthDay News) -- Intravenous corticosteroids are both safe and effective when used perioperatively in total knee or hip arthroplasty, with benefits including less pain, vomiting, and nausea, and fewer opioids, according to a review published online Aug. 29 in PAIN Practice.

Donghai Li, from West China Hospital in Chengdu, and colleagues conducted a systematic literature review and meta-analysis to assess the pain management effect of perioperative intravenous corticosteroids in patients undergoing total knee or hip arthroplasty.

Based upon 14 randomized controlled trials (1,023 patients), the researchers found that the use of intravenous steroids was associated with reduced pain at rest and with activity during the first 24 hours after surgery (P < 0.05). Additionally, patients in the steroid group had less opioid consumption (P < 0.05) and had better outcomes in terms of nausea and vomiting (both P < 0.05). Most complications were similar in both groups (P > 0.05), although the occurrence of venous thromboembolism was marginally lower in the corticosteroid group.

"Our results showed that intravenous corticosteroids have good efficacy and safety when used perioperatively in total knee or hip arthroplasty," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions


Sign up for myCME e-newsletters


More in Home

Amount of Opioids Prescribed After Hospital Discharge Varies

Amount of Opioids Prescribed After Hospital Discharge Varies

45.6 percent of patients using no opioids 24 hours predischarge were prescribed opioids at discharge

Observation Care Cost Saving in Commercially-Insured Patients

Observation Care Cost Saving in Commercially-Insured Patients

Total, out-of-pocket spending considerably lower for observation care; both increased from '09 to '13

Disrupted Sleep Linked to Increased Amyloid- Production

Disrupted Sleep Linked to Increased Amyloid-&#946; Production

Sleep deprivation tied to increased overnight amyloid-β-38, -40, -42 levels by 25 to 30 percent

is free, fast, and customized just for you!

Already a member?

Sign In Now »