Overweight Colorectal CA Patients Display Better Survival Odds

This article originally appeared here.
Share this content:
Overweight Colorectal CA Patients Display Better Survival Odds
Overweight Colorectal CA Patients Display Better Survival Odds

FRIDAY, May 20, 2016 (HealthDay News) -- Overweight colorectal cancer (CRC) patients may have better survival than their normal-weight peers, according to research published online May 19 in JAMA Oncology.

Candyce Kroenke, Sc.D., research scientist at the Kaiser Permanente Division of Research in Oakland, Calif., and colleagues examined the medical records of 3,408 patients in California diagnosed with stages I to III CRC between 2006 and 2011. The researchers then compared each patient's risk of death at the time of diagnosis and then over the following 15 months.

Patients who were either underweight or statistically obese at diagnosis had higher risk of mortality than low-normal weight patients (BMI 18.5 to <23 kg/m²). High-normal weight (BMI 23 to <25 kg/m²), low-overweight (BMI 25 to <28 kg/m²), and high-overweight (BMI 28 to <30 kg/m²) were associated with lower mortality risks (hazard ratios, 0.77 [95 percent confidence interval (CI), 0.56 to 1.06], 0.75 [95 percent CI, 0.55 to 1.04], and 0.52 [95 percent CI, 0.35 to 0.77], respectively).

"Our study, which represents the largest cohort of CRC patients with the most comprehensive data regarding patient weight before, at time of, and following diagnosis, supports the notion of the 'obesity paradox,'" Kroenke said in a Kaiser news release.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

FDA OKs Drug for Hemophilia A With Factor VIII Inhibitors

FDA OKs Drug for Hemophilia A With Factor ...

Weekly prophylactic treatment associated with substantial decrease in bleeding episodes

Risk of Falls Up With Mild, Moderate Diabetic Retinopathy

Risk of Falls Up With Mild, Moderate Diabetic ...

And perceived barriers to diabetes self-management are associated with severity of diabetic retinopathy

AMD Risk Has Dropped By Birth Cohort Throughout 20th Century

AMD Risk Has Dropped By Birth Cohort Throughout ...

Generational association remains significant after adjustment for age, sex, other confounders

is free, fast, and customized just for you!

Already a member?

Sign In Now »