Ovarian Preservation Doesn't Impact Prognosis in Cervical CA

Share this content:
Ovarian Preservation Doesn't Impact Prognosis in Cervical CA
Ovarian Preservation Doesn't Impact Prognosis in Cervical CA

THURSDAY, Oct. 13, 2016 (HealthDay News) -- For women with early-stage cervical adenocarcinoma, ovarian preservation does not impact survival, according to a study published in the October issue of the American Journal of Obstetrics & Gynecology.

Jing Chen, M.D., from Huazhong University of Science and Technology in Wuhan, China, and colleagues examined the impact of ovarian preservation on prognosis in a retrospective study involving 194 women with cervical adenocarcinoma. Follow-up was completed for 159 women. The authors compared the impact of ovarian preservation on prognosis for 33 women with ovarian preservation and 126 who underwent bilateral salpingo-oophorectomy.

The researchers found that survival did not differ significantly for women with bilateral salpingo-oophorectomy and ovarian preservation (P = 0.423 for disease-free survival and P = 0.330 for overall survival). Significant independent prognostic factors related to poor disease-free survival included tumor size (>4 cm), deep cervical stromal invasion, and lymph node metastasis; lymph node metastasis correlated with overall survival. There was a significant difference in the relationship between ovarian metastasis and deep cervical stromal invasion, lymph node metastasis, and parametrial invasion among the 153 women with cervical adenocarcinoma who underwent bilateral salpingo-oophorectomy. In meta-analysis of the literature, clinical stage IIB versus I to IIA, deep stromal invasion, lymph node metastasis, corpus uteri invasion, and parametrial invasion correlated with ovarian metastasis.

"Ovarian preservation has no effect on prognosis in women with early-stage cervical adenocarcinoma," the authors write.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

Basivertebral Nerve Ablation Beneficial for Chronic Back Pain

Basivertebral Nerve Ablation Beneficial for Chronic Back Pain

Improvement in self-reported outcomes at three months in patients with chronic lumbar back pain

FDA Approves Trulance for Chronic Idiopathic Constipation

FDA Approves Trulance for Chronic Idiopathic Constipation

Drug designed to stimulate secretion of intestinal fluid

ECG Could Be Used As Password for E-Health Record Access

ECG Could Be Used As Password for E-Health ...

Researchers say heartbeat could serve as a secure 'password' for patient's electronic medical history

is free, fast, and customized just for you!

Already a member?

Sign In Now »