October 2017 Briefing - Hematology & Oncology

Share this content:
Here are what the editors at HealthDay consider to be the most important developments in Hematology & Oncology for October 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Calquence Approved for Mantle Cell Lymphoma

TUESDAY, Oct. 31, 2017 (HealthDay News) -- Calquence (acalabrutinib) has been approved by the U.S. Food and Drug Administration to treat adults with mantle cell lymphoma.

More Information

Internists Key to Identifying Need for Genetic Counseling for Cancer

TUESDAY, Oct. 31, 2017 (HealthDay News) -- Internists play an important role in identifying which patients may be predisposed to cancer and could benefit from genetic counseling, according to an opinion piece published online Oct. 30 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Ultrasonography Not Necessary for Evaluation of Hypothyroidism

TUESDAY, Oct. 31, 2017 (HealthDay News) -- Imaging studies, including thyroid ultrasonography, are not required for the evaluation of hypothyroidism, and their risks include treatment of incidentally discovered nodules, patient and physician anxiety, and significant cost, according to a clinical review article published online Oct. 30 in JAMA Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Depressive Symptoms Increase During Internship Year

TUESDAY, Oct. 31, 2017 (HealthDay News) -- Depressive symptoms increase during the internship year for training physicians, with a greater increase among women, according to a study published online Oct. 30 in JAMA Internal Medicine.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Computed Tomography Features Vary Based on BRCA Status

THURSDAY, Oct. 31, 2017 (HealthDay News) -- Qualitative computed tomography (CT) features differ between patients with BRCA-mutant high-grade serous ovarian cancer (HGSOC) and patients with BRCA wild-type HGSOC, according to a study published in the November issue of Radiology.

Abstract/Full Text (subscription or payment may be required)

Multimodal Surveillance Regimen May Not Benefit BRCA Carriers

MONDAY, Oct. 30, 2017 (HealthDay News) -- Automated breast ultrasonography may not be of added value to yearly full-field digital (FFD) mammography and dynamic contrast agent-enhanced (DCE) magnetic resonance (MR) imaging surveillance of carriers of the BRCA mutation, according to a study published in the November issue of Radiology.

Abstract/Full Text (subscription or payment may be required)

More Than One in Five U.S. Working Adults Uses Tobacco

MONDAY, Oct. 30, 2017 (HealthDay News) -- Overall, 22.1 percent of working U.S. adults currently use any form of tobacco, according to a study published online Oct. 26 in Morbidity and Mortality Weekly Report.

Abstract/Full Text

Elastography and Color Doppler Improve Breast Ultrasound

MONDAY, Oct. 30, 2017 (HealthDay News) -- The combination of elastography and color Doppler ultrasonography (US) with B-mode US in women with dense breasts can increase the positive predictive value of screening and reduce the number of false-positives, according to a study published in the November issue of Radiology.

Abstract/Full Text (subscription or payment may be required)

Flow Cytometry Assesses Minimal Residual Disease in Myeloma

MONDAY, Oct. 30, 2017 (HealthDay News) -- Data on methods used for assessing minimal residual disease (MRD) in multiple myeloma (MM) are presented in a report published online Oct. 23 in the International Journal of Laboratory Hematology.

Abstract
Full Text

Treatment for Stage I NSCLC Patients Up From 2000 to 2010

FRIDAY, Oct. 27, 2017 (HealthDay News) -- For patients with stage I non-small-cell lung cancer (NSCLC), the odds of receiving radiation therapy (RT) or surgery increased from 2000 to 2010, with improved survival during the same period, according to a study published online Oct. 26 in the Annals of Thoracic Surgery.

Abstract/Full Text (subscription or payment may be required)

Multidisciplinary Model Cuts Treatment Delay in Head, Neck CA

FRIDAY, Oct. 27, 2017 (HealthDay News) -- For patients with head and neck cancer, a multidisciplinary head and neck clinic model is associated with reduced treatment delay, according to a study published online Oct. 26 in JAMA Otolaryngology -- Head & Neck Surgery.

Abstract/Full Text (subscription or payment may be required)

Gastric Cancer Incidence Down, Survival Up

FRIDAY, Oct. 27, 2017 (HealthDay News) -- Since 1984, there has been decreased incidence and increased survival rates for gastric cancer (GC), but long-term survival remains low, according to a study published online Oct. 19 in the Journal of Gastroenterology and Hepatology.

Abstract
Full Text (subscription or payment may be required)

70-Gene Signature Impacts Treatment Decisions in Breast CA

FRIDAY, Oct. 27, 2017 (HealthDay News) -- The 70-gene signature (GS) assay affects treatment decisions among physicians treating patients identified as being at intermediate risk with the 21-gene assay (21-GA), according to a study published online Oct. 26 in JAMA Oncology.

Abstract/Full Text

HER3 Linked to Improved Survival With Panitumumab

THURSDAY, Oct. 26, 2017 (HealthDay News) -- Higher HER3 expression is associated with improved survival with the addition of panitumumab treatment for patients with RAS wild-type (wt) advanced colorectal cancer, according to a study published online Oct. 26 in JAMA Oncology.

Abstract/Full Text (subscription or payment may be required)

Better Outcomes With Transoroal Robotic Surgery Alone in OPSCC

THURSDAY, Oct. 26, 2017 (HealthDay News) -- For patients with oropharyngeal squamous cell carcinoma (OPSCC), transoral robotic surgery (TORS) alone is associated with improved outcomes versus TORS followed by adjuvant treatment, according to a study published online Oct. 26 in JAMA Otolaryngology -- Head & Neck Surgery.

Abstract/Full Text

Cataract Surgery Associated With Reduced Mortality in Women

THURSDAY, Oct. 26, 2017 (HealthDay News) -- For older women with cataract, cataract surgery is associated with lower all-cause and cause-specific mortality, according to a study published online Oct. 26 in JAMA Ophthalmology.

Abstract/Full Text
Editorial (subscription or payment may be required)

Demand for Fertility Preservation Increasing for Women

THURSDAY, Oct. 26, 2017 (HealthDay News) -- The demand for fertility preservation is increasing, and methods to address it include oocyte cryopreservation and ovarian-tissue cryopreservation, according to a review article published online Oct. 25 in the New England Journal of Medicine.

Abstract/Full Text (subscription or payment may be required)

Gifts From Pharma Companies Influence Prescribing Behavior

THURSDAY, Oct. 26, 2017 (HealthDay News) -- Receipt of gifts from pharmaceutical companies is associated with more prescriptions per patient and more costly prescriptions, according to a study published online Oct. 25 in PLOS One.

Abstract/Full Text

Detectable Levels of Roundup Ingredient Rising in Older Adults

WEDNESDAY, Oct. 25, 2017 (HealthDay News) -- Detectable levels of glyphosate, the primary ingredient in the herbicide Roundup, have significantly increased in older adults over time, according to a research letter published online Oct. 24 in the Journal of the American Medical Association.

Abstract/Full Text (subscription or payment may be required)

Robotic Radical Nephrectomy Becoming More Common

WEDNESDAY, Oct. 25, 2017 (HealthDay News) -- From 2003 to 2015 there was an increase in use of robotic-assisted radical nephrectomy, according to a study published online Oct. 24 in the Journal of the American Medical Association. In a separate study, researchers found that robotic-assisted laparoscopic surgery for resection of rectal adenocarcinoma does not significantly reduce the risk of conversion to open surgery when compared with conventional laparoscopy.

Abstract/Full Text (subscription or payment may be required) -- Jeong
Abstract/Full Text (subscription or payment may be required) -- Jayne
Editorial (subscription or payment may be required)

Most Patients Satisfied With Relationship With Physician

WEDNESDAY, Oct. 25, 2017 (HealthDay News) -- Results of the Physicians Foundation 2017 Patient Survey show that most patients are satisfied with their overall relationship with their physician, according to an article published by the American Academy of Family Physicians.

More Information

Mechanism ID'd for Chemo-Related Peripheral Neuropathy

WEDNESDAY, Oct. 25, 2017 (HealthDay News) -- Researchers may have uncovered the mechanism for chemotherapy-induced peripheral neuropathy (CIPN) related to paclitaxel, according to a study published online Oct. 11 in Neuron.

Abstract/Full Text (subscription or payment may be required)

DEA Taking Back Unwanted Prescription Drugs on Oct. 28

TUESDAY, Oct. 24, 2017 (HealthDay News) -- The public is being given its 14th opportunity to safely dispose of pills and patches at collection points operated by the U.S. Drug Enforcement Agency (DEA) and its partners.

More Information

Swedish Massage May Reduce Cancer-Related Fatigue

TUESDAY, Oct. 24, 2017 (HealthDay News) -- Swedish massage therapy (SMT) is associated with clinically significant relief from cancer-related fatigue (CRF) in breast cancer survivors, according to a study published online Oct. 17 in Cancer.

Abstract
Full Text (subscription or payment may be required)

Ramucirumab Shows Promise in Care of Advanced Gastric Cancer

TUESDAY, Oct. 24, 2017 (HealthDay News) -- Ramucirumab appears to be safe and effective for the treatment of advanced gastric cancer, according to a study published online Sept. 29 in the Journal of Gastroenterology and Hepatology.

Abstract
Full Text (subscription or payment may be required)

Design Thinking Enables Med Students to Solve Challenges

MONDAY, Oct. 23, 2017 (HealthDay News) -- A joint effort between students at Warren Alpert Medical School of Brown University and Rhode Island School of Design (RISD) is training future physicians in design thinking to help identify and repair health system issues that contribute to physician burnout, according to an article by the American Medical Association.

More Information

Leukemia Patients Who Survive Severe GVHD Often Fare Worse

MONDAY, Oct. 23, 2017 (HealthDay News) -- After hematopoietic stem cell transplantation (HSCT) for acute leukemia, patients who survive severe acute graft-versus-host disease (aGVHD) have a higher risk of developing extensive chronic GVHD (cGVHD) and a higher rate of non-relapse mortality compared with those who did not develop severe aGVHD, according to a study published online Oct. 13 in the Journal of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

2003 to 2014 Saw Drop in Urinary Arsenic in Public Water Users

MONDAY, Oct. 23, 2017 (HealthDay News) -- From 2003 to 2014, urinary arsenic decreased among users of public water systems but not among private well users, according to a study published online Oct. 22 in the The Lancet Public Health.

Abstract/Full Text
Editorial

Limited Evidence of Benefit for Medical Cannabinoids in Children

MONDAY, Oct. 23, 2017 (HealthDay News) -- The strongest evidence for benefit of cannabinoids in children is for chemotherapy-induced nausea and vomiting, with more research needed to assess its role as a medical treatment, according to a review published online Oct. 23 in Pediatrics.

Abstract
Full Text (subscription or payment may be required)

Clinician Job Satisfaction Linked to Improved Burnout Scores

FRIDAY, Oct. 20, 2017 (HealthDay News) -- Clinicians' job satisfaction is associated with improved burnout scores and reduced intention to leave their practices, according to a study published in the October issue of Health Affairs.

Abstract
Full Text (subscription or payment may be required)

For Hepatitis B Patients, Aspirin Tied to Lower Risk of HCC

FRIDAY, Oct. 20, 2017 (HealthDay News) -- Aspirin therapy is associated with a reduced risk of hepatitis B virus-related hepatocellular carcinoma (HCC), according to a study scheduled for presentation at The Liver Meeting, held by the American Association for the Study of Liver Diseases from Oct. 20 to 24 in Washington, D.C.

Abstract 223
More Information

Oncogenic Oral HPV DNA Detected in 3.5 Percent of Adults

FRIDAY, Oct. 20, 2017 (HealthDay News) -- Men have a higher prevalence of oncogenic oral human papillomavirus (HPV) than women, and prevalence increases with the number of lifetime oral sexual partners and tobacco use, according to a study published online Oct. 19 in the Annals of Oncology.

Abstract/Full Text

In Norway, Risk of SCC After Organ Transplant Has Fallen

FRIDAY, Oct. 20, 2017 (HealthDay News) -- For organ recipients in Norway, the risk of skin cancer, particularly squamous cell carcinoma (SCC), has decreased since the mid-1980s, according to a study published online Oct. 18 in JAMA Dermatology.

Abstract/Full Text

Melanoma Staging Undergoes Evidence-Based Revision

FRIDAY, Oct. 20, 2017 (HealthDay News) -- The American Joint Committee on Cancer (AJCC) melanoma staging system has been revised, according to a report published online Oct. 13 in CA: A Cancer Journal for Clinicians.

Abstract/Full Text

Cryotherapy May Prevent Chemo-Induced Neuropathy

FRIDAY, Oct. 20, 2017 (HealthDay News) -- Cryotherapy may be useful for preventing symptoms of chemotherapy-induced peripheral neuropathy (CIPN), according to a study published online Oct. 12 in the Journal of the National Cancer Institute.

Abstract/Full Text (subscription or payment may be required)

Gene Tx Approved for Certain Types of B-Cell Lymphoma

THURSDAY, Oct. 19, 2017 (HealthDay News) --Yescarta (axicabtagene ciloleucel) has been approved by the U.S. Food and Drug Administration for individuals with certain types of large B-cell lymphoma who have not responded to or who have relapsed after at least two other kinds of treatment.

More Information

Uninsurance Down by One-Third for Cancer Diagnoses in 2014

THURSDAY, Oct. 19, 2017 (HealthDay News) -- In the first year of the Affordable Care Act (ACA), there was a relative decrease of one-third in uninsurance among adults with new cancer diagnoses, according to a research letter published online Oct. 19 in JAMA Oncology.

Abstract/Full Text (subscription or payment may be required)

Conditions Tied to Clinician Dissatisfaction Are Modifiable

THURSDAY, Oct. 19, 2017 (HealthDay News) -- Modifiable conditions, like chaos, incohesiveness, and lack of communication, contribute to unsatisfying workplaces for clinicians, according to a study published in the October issue of Health Affairs.

Abstract
Full Text (subscription or payment may be required)

Gene Expression Assay Classifies Diffuse Large B-Cell Lymphoma

THURSDAY, Oct. 19, 2017 (HealthDay News) -- A novel gene expression profiling diffuse large B-cell lymphoma (DLBCL) classifier, which evaluates the expression of 21 markers, is effective for classifying samples, according to a study published online Oct. 17 in the Journal of Molecular Diagnostics.

Abstract/Full Text (subscription or payment may be required)

Key Stakeholders Discuss How to Make EHRs More Usable

THURSDAY, Oct. 19, 2017 (HealthDay News) -- Key stakeholders and physicians discussed electronic health record (EHR) usability and optimization in the American Medical Association Running Your Practice Community.

More Information

Oral Antibiotics Cut Risk of SSI in Colorectal CA Resection

WEDNESDAY, Oct. 18, 2017 (HealthDay News) -- For patients undergoing left colon and rectal cancer resections, the addition of oral antibiotics to mechanical bowel preparation (MBP) is associated with a reduced rate of surgical site infections (SSIs), according to a study published online Oct. 18 in JAMA Surgery.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Sharing Passwords Is Widespread Among Medical Staff

WEDNESDAY, Oct. 18, 2017 (HealthDay News) -- Sharing of passwords to access electronic medical records is common among medical staff members, according to a study published in the July issue of Healthcare Informatics Research.

Abstract/Full Text

Men Now Comprise ~10 Percent of RN Workforce

WEDNESDAY, Oct. 18, 2017 (HealthDay News) -- The increasing participation of men in registered nursing can be attributed to multiple factors, including increasing educational attainment, rising labor demand in health care, and liberalizing gender role attitudes, according to a working paper published by the Washington Center for Equitable Growth.

Abstract
Full Text

Visceral Adipose Tissue Index IDs Risk of HCC in Cirrhosis

WEDNESDAY, Oct. 18, 2017 (HealthDay News) -- For male patients with cirrhosis, visceral adipose tissue index (VATI) is an independent risk factor for hepatocellular carcinoma (HCC), according to a study published online Oct. 10 in Hepatology.

Abstract
Full Text (subscription or payment may be required)

Overall Survival Up for Melanoma Brain Metastases

WEDNESDAY, Oct. 18, 2017 (HealthDay News) -- Overall survival (OS) for patients with melanoma brain metastases (MBM) has improved significantly since 2000, according to a study published online Oct. 12 in Cancer.

Abstract
Full Text (subscription or payment may be required)

Machine Learning Model Predicts Risk of Upgrade to Breast CA

TUESDAY, Oct. 17, 2017 (HealthDay News) -- A machine learning model can predict the risk of upgrade of high-risk breast lesions (HRLs) to cancer, according to a study published online Oct. 17 in Radiology.

Abstract/Full Text (subscription or payment may be required)

Mortality Up for Male Recipients of Blood From Ever-Pregnant

TUESDAY, Oct. 17, 2017 (HealthDay News) -- For males, receipt of a red blood cell transfusion from an ever-pregnant female is associated with increased rate of all-cause mortality compared with a male donor, according to a study published online Oct. 17 in the Journal of the American Medical Association.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Prevalence of Oral HPV Infection Higher for U.S. Men

TUESDAY, Oct. 17, 2017 (HealthDay News) -- Oral human papillomavirus (HPV) infection and high-risk oral HPV infection are more common among men than women, according to a study published online Oct. 16 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Gastric Acid Suppression May Promote Liver Injury

TUESDAY, Oct. 17, 2017 (HealthDay News) -- Based on data from mouse models and humans, a decrease in gastric acid secretion due to use of gastric acid suppressive medications seems to promote overgrowth of intestinal Enterococcus, which promotes liver disease, according to a study published online Oct. 10 in Nature Communications.

Abstract/Full Text

'Liquid Biopsy' Shows Promise for Hepatocellular Carcinoma

TUESDAY, Oct. 17, 2017 (HealthDay News) -- 'Liquid biopsy' technology holds promise for diagnosing, monitoring, and predicting prognosis in patients with hepatocellular carcinoma (HCC), according to a study published online Oct. 9 in Nature Materials.

Abstract/Full Text (subscription or payment may be required

Female Physicians May Be Especially at Risk of Burnout

TUESDAY, Oct. 17, 2017 (HealthDay News) -- Female physicians are more burned out than their male colleagues, but there are steps they can take to reduce the stress associated with burnout, according to a blog post published in Medical Economics.

More Information

Most Female Physicians Have Faced Sexist Patient Comments

MONDAY, Oct. 16, 2017 (HealthDay News) -- Most female physicians have been sexually harassed by patients at some point in their careers, according to a blog post published in Medical Economics.

More Information

Online Ratings Not Aligned With Objective Quality Measures

MONDAY, Oct. 16, 2017 (HealthDay News) -- Online consumer ratings of specialist physicians do not predict objective measures of quality of care or peer assessment of clinical performance, according to a study published online Sept. 8 in the Journal of the American Medical Informatics Association.

Abstract/Full Text (subscription or payment may be required)

Increase in Rate of Breast Reconstruction for Mastectomy

MONDAY, Oct. 16, 2017 (HealthDay News) -- From 2009 to 2014 there was an increase in the population rate of breast reconstruction for mastectomy, which was seen for all age groups, according to a report published in an October Statistical Brief of the Agency for Healthcare Research and Quality.

Abstract/Full Text

Model Predicts Cost-Effectiveness for Anal Lesion Treatment

MONDAY, Oct. 16, 2017 (HealthDay News) -- Cost-effective management of precancerous anal intraepithelial lesions in HIV-positive men who have sex with men (MSM) varies by age, according to a study published online Sept. 26 in Cancer.

Abstract
Full Text (subscription or payment may be required)

Serious Suffering Affects Almost Half of Those Who Die Yearly

FRIDAY, Oct. 13, 2017 (HealthDay News) -- In 2015, more than 25.5 million people who died worldwide experienced serious health-related suffering (SHS), and the vast majority lacked access to palliative care and pain relief, according to a report published online Oct. 12 in The Lancet.

Abstract/Full Text
Editorial

Pre-Retirement Morbidity Higher in Later Birth Cohorts

FRIDAY, Oct. 13, 2017 (HealthDay News) -- Americans who must work longer to reach Social Security retirement age have worse measures of health in the years leading up to retirement, according to a study published in the October issue of Health Affairs.

Abstract
Full Text (subscription or payment may be required)

Aqueous Humor Can Serve as Surrogate Tumor Biopsy

FRIDAY, Oct. 13, 2017 (HealthDay News) -- A novel method will allow for analyses of tumor-derived DNA in eyes with retinoblastoma (Rb) undergoing salvage therapy that have not been enucleated, according to a study published online Oct. 12 in JAMA Ophthalmology.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Quality Issues for Both Paper-, Electronic-Based Health Records

FRIDAY, Oct. 13, 2017 (HealthDay News) -- Both paper-based and electronic health records (EHRs) have shortcomings in terms of quality of content, process, and structure, with poor quality of nursing documentation seen for both methods, according to a study published online Oct. 5 in the Journal of Clinical Nursing.

Abstract
Full Text (subscription or payment may be required)

U.S. Filipinos Have Higher Thyroid Cancer Mortality

FRIDAY, Oct. 13, 2017 (HealthDay News) -- Filipinos die of thyroid cancer at higher rates than non-Filipino Asian (NFA) and non-Hispanic white (NHW) individuals of similar ages, according to a study published online Sept. 7 in Cancer.

Abstract
Full Text (subscription or payment may be required)

Across U.S., Wide Variation Seen in Thyroidectomy Rates

THURSDAY, Oct. 12, 2017 (HealthDay News) -- There is wide variation in thyroidectomy rates among Medicare beneficiaries nationally, suggesting widely divergent local practice patterns for the management of thyroid nodules and cancer, according to a study published online Oct. 12 in JAMA Otolaryngology -- Head & Neck Surgery.

Abstract/Full Text

Genetic Variant Tied to Prostate Cancer Outcomes

THURSDAY, Oct. 12, 2017 (HealthDay News) -- The HSD3B1 (1245C) allele is associated with more rapid development of metastases in men with biochemically recurrent prostate cancer, and it predicts response to nonsteroidal CYP17A1 inhibition, according to two studies published online Oct. 12 in JAMA Oncology.

Abstract/Full Text (subscription or payment may be required) -- Hearn
Abstract/Full Text (subscription or payment may be required) -- Almassi
Editorial (subscription or payment may be required)

Court Considering Fate of Noneconomic Damages Cap

THURSDAY, Oct. 12, 2017 (HealthDay News) -- The Wisconsin Supreme Court is considering whether it will hear a case that will determine the fate of the state's $750,000 cap on noneconomic damages, according to an article published by the American Medical Association (AMA).

More Information

New System Streamlines CME Credit Approval Process

THURSDAY, Oct. 12, 2017 (HealthDay News) -- The American Academy of Family Physicians (AAFP) and the American Board of Family Medicine (ABFM) have launched a new performance improvement activity credit reporting process called the AAFP Credit System, according to an article published by the AAFP.

More Information

Neurotoxicity Characterized After Infusion of CD19 CAR-T Cells

THURSDAY, Oct. 12, 2017 (HealthDay News) -- Patients with severe neurotoxicity after infusion of CD19-targeted chimeric antigen receptor-modified T (CAR-T) cells have evidence of endothelial activation, according to a study published online Oct. 12 in Cancer Discovery.

Abstract/Full Text (subscription or payment may be required)

Primary, Pulmonary Providers Endorse Lung CA Screening

THURSDAY, Oct. 12, 2017 (HealthDay News) -- Primary care clinicians and pulmonologists endorse lung cancer screening (LCS), but there are limitations in their knowledge of screening components, according to a study published online Sept. 21 in the Annals of the American Thoracic Society.

Abstract
Full Text (subscription or payment may be required)

Low-Cost Services a Major Player in Unnecessary Health Spending

THURSDAY, Oct. 12, 2017 (HealthDay News) -- The costs associated with low-cost, low-value health services are nearly twice as high as those of high-cost, low-value services, according to a study published in the October issue of Health Affairs.

Abstract
Full Text (subscription or payment may be required)

Medical License Questions Sway Doctors' Mental Health Help

WEDNESDAY, Oct. 11, 2017 (HealthDay News) -- Medical licensure application questions (MLAQs) regarding mental health contribute to physicians' reluctance to seek help for mental health, according to a study published in the October issue of Mayo Clinic Proceedings.

Abstract
Full Text

Physician Salaries Appear to Be Flat or Declining

WEDNESDAY, Oct. 11, 2017 (HealthDay News) -- Anecdotally, physician career coaches report that physician salaries are flat at best, according to an article published in Medical Economics.

More Information

New Tool IDs Mortality Risk After Bladder Cancer Surgery

WEDNESDAY, Oct. 11, 2017 (HealthDay News) -- A new risk-stratification tool is able to estimate mortality in patients with urothelial carcinoma of the bladder (UCB) after cystectomy, according to a study published online Sept. 7 in Cancer.

Abstract
Full Text (subscription or payment may be required)

HPV Vaccination After Lesion Treatment Is Likely Cost-Effective

WEDNESDAY, Oct. 11, 2017 (HealthDay News) -- For HIV-infected men who have sex with men (MSM), adjuvant quadrivalent human papillomavirus vaccination (qHPV) after treatment of high-grade squamous intraepithelial lesions (HSIL) is likely to be cost-effective, according to a study published online Sept. 12 in Vaccine.

Abstract/Full Text (subscription or payment may be required)

Guide Offers Doctors Tips for Choosing a Health System

TUESDAY, Oct. 10, 2017 (HealthDay News) -- A guide has been developed to assist physicians considering joining a physician-led integrated health system, according to a report published by the American Medical Association (AMA).

More Information

Novel Metrics Suggested for Assessing EHR Use

TUESDAY, Oct. 10, 2017 (HealthDay News) -- Novel metrics have been developed to assess electronic health record (EHR) use and are described in an opinion article published online Oct. 9 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Patient, Provider Interventions May Up Colonoscopy Rates

TUESDAY, Oct. 10, 2017 (HealthDay News) -- For asymptomatic adults with positive fecal blood test results, patient navigators and provider reminders or performance data may help improve colonoscopy rates; however, current evidence about useful system-level interventions is insufficient, according to a review published online Oct. 9 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

2016 Physician Quality Reporting System Reports Available

MONDAY, Oct. 9, 2017 (HealthDay News) -- The 2016 Physician Quality Reporting System (PQRS) and the 2016 annual Quality and Resource Use reports have been released for individuals and group practices, according to a report published by the American Academy of Family Physicians.

More Information

Injured Patients Want More Info on Safety Improvement Efforts

MONDAY, Oct. 9, 2017 (HealthDay News) -- Communication-and-resolution program (CRP) experiences are positive overall for a small majority of patients and families, but they report that hospitals rarely share information about preventing recurrences, according to a study published online Oct. 9 in JAMA Internal Medicine.

Abstract/Full Text
Editorial

Negative Margins, Lymph Node Yields Predict Survival

MONDAY, Oct. 9, 2017 (HealthDay News) -- Patients treated at hospitals that attain a high rate of negative margins and lymph node yields (LNY) of at least 18 have improved survival after surgery for head and neck squamous cell carcinomas (HNSCC), according to a study published online Oct. 5 in JAMA Otolaryngology -- Head & Neck Surgery.

Abstract/Full Text (subscription or payment may be required)

First Test to Detect Zika in Blood Donations Approved

FRIDAY, Oct. 6, 2017 (HealthDay News) -- The cobas Zika test has been approved by the U.S. Food and Drug Administration -- the first approved screening test to detect the Zika virus in blood donations.

More Information

Short-Lived Benefits for Abusive Supervisory Behavior

FRIDAY, Oct. 6, 2017 (HealthDay News) -- Engaging in abusive supervisory behavior may be associated with short-term beneficial effects, but over longer periods of time, abusive supervisory behavior is negatively related to supervisors' recovery level and engagement, according to a study published online Sept. 11 in the Academy of Management Journal.

Abstract
Full Text (subscription or payment may be required)

Stronger Nocebo Effect When Inert Rx Labeled As Expensive

FRIDAY, Oct. 6, 2017 (HealthDay News) -- Nocebo hyperalgesia is stronger when an inert treatment is labeled as being an expensive medication rather than a cheap one, according to a study published online Oct. 5 in Science.

Abstract
Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Most Cancer Drugs Approved in Europe Show No Survival Benefit

FRIDAY, Oct. 6, 2017 (HealthDay News) -- Most cancer drugs that enter the market in Europe have no evidence of benefit for survival or quality of life, according to a study published online Oct. 4 in BMJ.

Abstract/Full Text
Editorial

Liver Cancer Remains a Major Public Health Burden Globally

FRIDAY, Oct. 6, 2017 (HealthDay News) -- Causes of primary liver cancer differ widely among populations globally, but most cases can be prevented, according to a study published online Oct. 5 in JAMA Oncology.

Abstract/Full Text

21 Percent of Americans Report Experiencing a Medical Error

THURSDAY, Oct. 5, 2017 (HealthDay News) -- More than one in five patients report having experienced a medical error, according to a survey released Sept. 28 by the Institute for Healthcare Improvement (IHI)/National Patient Safety Foundation Lucian Leape Institute and NORC at the University of Chicago.

More Information

Reasons Physicians Are Delaying Retirement Vary

THURSDAY, Oct. 5, 2017 (HealthDay News) -- Physicians are delaying retirement, often because they feel they are providing a useful service to patients or because of concerns about social interaction in retirement, according to an article published online Sept. 25 in Medical Economics.

More Information

PFS Up With Obinutuzumab-Based Tx in Follicular Lymphoma

THURSDAY, Oct. 5, 2017 (HealthDay News) -- For patients with follicular lymphoma, obinutuzumab-based immunochemotherapy is associated with longer progression-free survival than rituximab-based therapy, according to a study published online Oct. 4 in the New England Journal of Medicine.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Pay Inequality, Work-Life Balance Top Concerns for Female Docs

WEDNESDAY, Oct. 4, 2017 (HealthDay News) -- Many female physicians report feeling disadvantaged when negotiating contracts and feel that they are assessed for promotion using different criteria than those used for men, according to a report published by the American Medical Association (AMA).

More Information

Provider Advice Impacts Breast Cancer Prevention Decisions

WEDNESDAY, Oct. 4, 2017 (HealthDay News) -- For patients at high risk for breast cancer, health care provider (HCP) recommendation is the most important factor for deciding whether to use selective estrogen receptor modulators (SERMs), according to a study published online Oct. 4 in Cancer Prevention Research.

Abstract/Full Text (subscription or payment may be required)

Insurance Type Linked to Surgery Delay in Melanoma

WEDNESDAY, Oct. 4, 2017 (HealthDay News) -- Patients diagnosed with melanoma are more likely to have treatment delays if they are nonwhite or on Medicaid, while delays are less likely for patients diagnosed or treated by a dermatologist, according to a study published online Oct. 4 in JAMA Dermatology.

Abstract/Full Text
Editorial (subscription or payment may be required)

Rate of Obesity-, Overweight-Related Cancers High in the U.S.

WEDNESDAY, Oct. 4, 2017 (HealthDay News) -- The burden of overweight- and obesity-related cancer is high in the United States, and incidence has increased in some states and age groups, according to a study published online Oct. 3 in Morbidity and Mortality Weekly Report.

Abstract/Full Text

Anticoagulants With Other Drugs Raise Bleeding Risk in AF

WEDNESDAY, Oct. 4, 2017 (HealthDay News) -- Nonvalvular atrial fibrillation (AF) patients who take non-vitamin K oral anticoagulants (NOACs) along with certain other medications are at increased risk for major bleeding, and antithrombotic medications are significantly associated with increased rates of hematuria-related complications in older adults, according to two studies published online Oct. 3 in the Journal of the American Medical Association.

Abstract/Full Text -- Chang (subscription or payment may be required)
Abstract/Full Text -- Wallis (subscription or payment may be required)

Increase in Number of Centers Doing Robotic Prostatectomy

WEDNESDAY, Oct. 4, 2017 (HealthDay News) -- The number of centers performing robotic surgery for radical prostatectomy increased during 2010 to 2014, according to a study published online Oct. 3 in The Lancet Oncology.

Abstract/Full Text
Editorial

Smoking Cessation Support Less Likely for Cancer Patients

WEDNESDAY, Oct. 4, 2017 (HealthDay News) -- General practitioners are less likely to support cessation of smoking in patients with cancer than in those with coronary heart disease (CHD), according to a study published online Sept. 11 in the Annals of Family Medicine.

Abstract
Full Text

Scientists Support Genome Editing to Prevent Disease

WEDNESDAY, Oct. 4, 2017 (HealthDay News) -- Many basic scientists and clinical researchers support somatic genome editing in adults for prevention of serious disease but not for human enhancement; they also believe the public should be consulted before any clinical application of germline gene editing proceeds, according to survey results published online Oct. 3 in Circulation: Cardiovascular Genetics.

Abstract/Full Text (subscription or payment may be required)

Process Promising for On-Site Printing of Custom-Dosed Meds

WEDNESDAY, Oct. 4, 2017 (HealthDay News) -- Small molecular medicines can be printed precisely using organic vapor jets, according to a study published online Sept. 27 in Nature Communications.

Abstract/Full Text

Overall Breast Cancer Incidence Up for Some in 2005-2014

TUESDAY, Oct. 3, 2017 (HealthDay News) -- Overall breast cancer incidence rates increased among specific racial/ethnic groups from 2005 to 2014, although the overall death rates decreased from 1989 to 2015, according to a study published online Oct. 3 in CA: A Cancer Journal for Clinicians.

Abstract/Full Text

Communication Program Doesn't Raise Hospital Liability Costs

TUESDAY, Oct. 3, 2017 (HealthDay News) -- A communication-and-resolution program, in which hospitals and liability insurers communicate with patients when adverse events occur, does not lead to higher liability costs, according to a study published online Oct. 2 in Health Affairs.

Abstract
Full Text (subscription or payment may be required)

Fewer Deaths Projected With Switch to Electronic Cigarettes

TUESDAY, Oct. 3, 2017 (HealthDay News) -- Replacement of cigarettes with electronic cigarettes (e-cigarettes) is projected to result in fewer premature deaths, even under a pessimistic scenario, according to a study published online Oct. 2 in Tobacco Control.

Abstract/Full Text

Sodium-Glucose Cotransporter 2 Inhibitors Not Cancer Risk Factor

TUESDAY, Oct. 3, 2017 (HealthDay News) -- Over the short term there is not a significantly increased overall cancer risk among individuals with type 2 diabetes using sodium-glucose cotransporter 2 (SGLT2) inhibitors, according to a study published in the October issue of Diabetologia.

Abstract/Full Text (subscription or payment may be required)

Adding Surveillance to FIT Screening Cuts CRC Mortality

TUESDAY, Oct. 3, 2017 (HealthDay News) -- Adding surveillance to fecal immunochemical test (FIT) screening reduces colorectal cancer (CRC) mortality and increases colonoscopy demand, according to a study published online Oct. 2 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Tattoo Pigment Hypersensitivity Can Mimic Lymphoma

TUESDAY, Oct. 3, 2017 (HealthDay News) -- Tattoo pigment hypersensitivity causing widespread lymphadenopathy has been described in a case report published online Oct. 2 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Opioid Manufacturers to Provide Doctor Training

MONDAY, Oct. 2, 2017 (HealthDay News) -- In an effort to halt the ongoing opioid addiction crisis, U.S. regulators are requiring manufacturers to provide extensive training to doctors, according to a report published by the Associated Press.

More Information

Legal Cannabis Use Common Among Cancer Patients

MONDAY, Oct. 2, 2017 (HealthDay News) -- In Washington state, where cannabis is legal, cancer patients have high rates of active use, and they report that legalization was an important factor in their decision to use, according to a study published online Sept. 25 in Cancer.

Abstract/Full Text

Hypermutated ctDNA Linked to Checkpoint Inhibitor Response

MONDAY, Oct. 2, 2017 (HealthDay News) -- For patients with diverse malignancies, hypermutated blood-derived circulating tumor DNA (ctDNA) is associated with checkpoint inhibitor response, according to a study published online Oct. 2 in Clinical Cancer Research.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

NTproBNP Levels Are Significantly Lower in Blacks

NTproBNP Levels Are Significantly Lower in Blacks

Higher NTproBNP levels linked to increased risk of death; this association did not differ by race

Data May Weigh on Pros/Cons of Expanded Care Optometry

Data May Weigh on Pros/Cons of Expanded Care ...

Majority of residents in Kentucky, Oklahoma, New Mexico live within 30 minutes of ophthalmologist

Gaps Seen Between Hearing Loss, Receipt of Medical Evaluation, Tx

Gaps Seen Between Hearing Loss, Receipt of Medical ...

About 20.6 percent of those with hearing less than excellent/good had visited doctor for hearing issues

is free, fast, and customized just for you!

Already a member?

Sign In Now »