October 2016 Briefing - Diabetes & Endocrinology

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for October 2016. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Diabetes-Related Distress Ups Risk for Rx Nonadherence

MONDAY, Oct. 31, 2016 (HealthDay News) -- Diabetes-related distress and depression symptom severity are risk factors for medication nonadherence in type 2 diabetes, according to a study published online Oct. 17 in Diabetes Care.

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Few Changes in Employer-Sponsored Insurance 2013-2014

MONDAY, Oct. 31, 2016 (HealthDay News) -- Private sector employer-sponsored health insurance offerings were similar in 2013 and 2014, with <3.5 percent of employers dropping coverage and 1.1 percent adding coverage, according to a report published online Oct. 26 in Health Affairs.

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Male Contraceptive Effective, but Side Effects Problematic

FRIDAY, Oct. 28, 2016 (HealthDay News) -- A contraceptive injection for men shows some promise, but researchers are still struggling to improve its effectiveness and deal with severe side effects caused by the injections, according to a study published online Oct. 27 in the Journal of Clinical Endocrinology & Metabolism.

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Study Duration Affects Rate of Diabetes Remission Post-RYGB

FRIDAY, Oct. 28, 2016 (HealthDay News) -- After Roux-en-Y gastric bypass (RYGB) surgery, variations in rates of diabetes remission are primarily related to differences in the definition of remission and study duration, according to a review published online Oct. 13 in Diabetes Care.

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Cardiometabolic Syndrome Ups Subclinical Atherosclerosis Risk

FRIDAY, Oct. 28, 2016 (HealthDay News) -- Cardiometabolic syndrome (CMS) is associated with increased risk of subclinical atherosclerosis, but the risk is attenuated by high fitness, according to a study published in the Nov. 1 issue of The American Journal of Cardiology.

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Education Needed Regarding Use of Herbal Weight Loss Products

FRIDAY, Oct. 28, 2016 (HealthDay News) -- Health care professionals need education about the safety and effectiveness of weight loss medications, according to a study published online Oct. 22 in the Journal of Pharmacy Practice and Research.

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Useful Tips Offered for Addressing Negative Patient Reviews

FRIDAY, Oct. 28, 2016 (HealthDay News) -- In an article published in Medical Economics, five tips are presented to address negative patient reviews.

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Lower Costs for Pregabalin in Peripheral Neuropathic Pain

THURSDAY, Oct. 27, 2016 (HealthDay News) -- For patients with peripheral neuropathic pain (PNP), the adjusted cost per patient is lower for treatment with pregabalin than gabapentin, according to a study published online Sept. 27 in the Journal of Evaluation in Clinical Practice.

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Socioeconomic Status in Children Tied to MetS in Adulthood

THURSDAY, Oct. 27, 2016 (HealthDay News) -- Family socioeconomic status (SES) in childhood is associated with the risk for metabolic syndrome (MetS) and glucose abnormalities in adulthood, according to a study published online Oct. 18 in Diabetes Care.

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New ADA Guidelines Call for More Frequent Activity for DM Patients

THURSDAY, Oct. 27, 2016 (HealthDay News) -- Patients with diabetes should do three or more minutes of light activity every 30 minutes during prolonged periods of sitting, such as working on a computer or watching television, according to the latest recommendations from the American Diabetes Association (ADA) published in the November issue of Diabetes Care.

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Bariatric Surgery May Be Cost-Effective in Severely Obese Teens

WEDNESDAY, Oct. 26, 2016 (HealthDay News) -- Bariatric surgery not only helps severely obese teens lose weight, it may pay for itself in health care savings over time, according to a study published online Oct. 26 in JAMA Surgery.

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Ratio of ω-6:ω-3 Fatty Acids Implicated in Obesity

WEDNESDAY, Oct. 26, 2016 (HealthDay News) -- Governments and international organizations should focus on redressing the balance of ω-6 and ω-3 fatty acids in order to address obesity, according to an editorial published in the September issue of Open Heart.

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Statins Offset Insulin-Related Cancer Risk in T2DM

WEDNESDAY, Oct. 26, 2016 (HealthDay News) -- For patients with type 2 diabetes mellitus (T2DM), use of statins offsets insulin-related cancer risks, according to research published online Oct. 21 in the Journal of Internal Medicine.

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Liraglutide Increases Heart Rate in T2DM With Stable CAD

TUESDAY, Oct. 25, 2016 (HealthDay News) -- Liraglutide increases heart rate (HR) and reduces heart rate variability (HRV) in overweight patients with newly diagnosed type 2 diabetes (T2D) and stable coronary artery disease (CAD), according to a study published online Oct. 19 in Diabetes Care.

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Saxagliptin Linked to Improved Albumin/Creatinine Ratios

MONDAY, Oct. 24, 2016 (HealthDay News) -- For patients with type 2 diabetes, saxagliptin is associated with improvement in the albumin/creatinine ratio (ACR), according to a study published online Oct. 17 in Diabetes Care.

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Continued 2 Percent Daily Testosterone Safe, Effective

MONDAY, Oct. 24, 2016 (HealthDay News) -- Once-daily testosterone solution 2 percent (T-sol) is safe and improves sex drive and energy in men with androgen deficiency, according to a study published in the November issue of The Journal of Urology.

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Fewer Uncertain Thyroid Results With Core Needle vs Repeat FNA

MONDAY, Oct. 24, 2016 (HealthDay News) -- To reduce inconclusive results for thyroid nodules, core-needle biopsy (CNB) is more effective than repeat fine-needle aspiration (FNA), according to a study published online Oct. 5 in Head & Neck.

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Resveratrol Doesn't Improve Insulin Sensitivity

MONDAY, Oct. 24, 2016 (HealthDay News) -- Resveratrol supplementation does not improve hepatic or peripheral insulin sensitivity among patients with type 2 diabetes, according to a study published online Oct. 7 in Diabetes Care.

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More Support for Health Benefits of Chocolate

FRIDAY, Oct. 21, 2016 (HealthDay News) -- A new analysis of existing studies, published online Sept. 28 in the Journal of Nutrition, provides more support for the idea that cocoa in chocolate may provide some health benefits.

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Switching Diet Drinks for Water Benefits Overweight Women

FRIDAY, Oct. 21, 2016 (HealthDay News) -- For overweight and obese women with type 2 diabetes, replacement of diet beverages (DBs) with water is associated with greater weight reduction and improvements in glucose metabolism, according to a study published online Oct. 16 in Diabetes, Obesity and Metabolism.

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Resveratrol Reduces Ovarian, Adrenal Androgens in PCOS

THURSDAY, Oct. 20, 2016 (HealthDay News) -- For patients with polycystic ovary syndrome (PCOS), resveratrol is associated with significant reductions in ovarian and adrenal androgens, according to a study published online Oct. 18 in the Journal of Clinical Endocrinology & Metabolism.

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Neonatal Phototherapy Not Linked to Type 1 Diabetes

THURSDAY, Oct. 20, 2016 (HealthDay News) -- Neonatal phototherapy is not associated with type 1 diabetes mellitus (DM-1), according to a study published online Oct. 19 in Pediatrics.

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Lower Bone Density Seen in Heavy Users of Cannabis

THURSDAY, Oct. 20, 2016 (HealthDay News) -- Heavy cannabis users have lower bone density compared to cigarette smokers, according to a new study published online Sept. 1 in The American Journal of Medicine.

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Barriers for Diabetic Retinopathy Screening Vary

THURSDAY, Oct. 20, 2016 (HealthDay News) -- Patients and health care providers have markedly divergent perceptions of barriers to diabetic retinopathy screening, according to a study published in the Oct. 6 issue of the U.S. Centers for Disease Control and Prevention's Preventing Chronic Disease.

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Considerable Absenteeism Costs for Chronic Disease, Risk Factors

WEDNESDAY, Oct. 19, 2016 (HealthDay News) -- Considerable costs are associated with absenteeism related to chronic diseases and health risk factors, according to a study published in the Oct. 6 issue of the U.S. Centers for Disease Control and Prevention's Preventing Chronic Disease.

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Treated Diabetic Retinopathy Rare in Children With T1DM

WEDNESDAY, Oct. 19, 2016 (HealthDay News) -- Treated diabetic retinopathy (DR) is extremely rare among children with type 1 diabetes, according to research published online Oct. 7 in Diabetes Care.

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Postprandial Walk Beneficial in Type 2 Diabetes

TUESDAY, Oct. 18, 2016 (HealthDay News) -- For patients with type 2 diabetes, a short walk after eating may help lower blood glucose levels more than exercising at other times of the day, according to research published online Oct. 17 in Diabetologia.

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SHBG, Total Estradiol Linked to Type 2 Diabetes in Women

TUESDAY, Oct. 18, 2016 (HealthDay News) -- For women, sex hormone-binding globulin (SHBG) and total estradiol (TE) are associated with the risk of type 2 diabetes (T2D), according to research published online Oct. 10 in Diabetes.

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Income Predicts Receipt of Weight-Loss Advice

MONDAY, Oct. 17, 2016 (HealthDay News) -- For overweight or obese individuals, income predicts receipt of weight-loss advice from health care providers, according to a study published in the Oct. 6 issue of the U.S. Centers for Disease Control and Prevention's Preventing Chronic Disease.

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Quality of Outpatient Care Has Not Consistently Improved in U.S.

MONDAY, Oct. 17, 2016 (HealthDay News) -- Efforts to improve the quality of clinical care in the United States have had little impact on many aspects of outpatient care, according to an analysis published online Oct. 17 in JAMA Internal Medicine.

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Adolescent BMI Predicts Diabetes Mellitus Mortality

MONDAY, Oct. 17, 2016 (HealthDay News) -- Adolescent body mass index (BMI) predicts diabetes mellitus (DM) mortality in midlife, according to a study published online Oct. 12 in Diabetes Care.

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Lower Monthly Premiums for Narrow-Network Plans

MONDAY, Oct. 17, 2016 (HealthDay News) -- Narrow-network health insurance plans have lower monthly premiums than larger-network plans, according to a study published in the October issue of Health Affairs.

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Androgen Deprivation Therapy May Raise Dementia Risk

FRIDAY, Oct. 14, 2016 (HealthDay News) -- The risk of dementia might be doubled for prostate cancer patients who are treated with androgen-deprivation therapy (ADT), according to a study published online Oct. 13 in JAMA Oncology.

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Half of U.S. Women Expect to Have Child in the Future

THURSDAY, Oct. 13, 2016 (HealthDay News) -- Fifty percent of U.S. women aged 15 to 44 years expect to have a child in the future, according to an October data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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Second Trimester Lipids Can ID Gestational Diabetes

THURSDAY, Oct. 13, 2016 (HealthDay News) -- Early second trimester lipids can identify maternal gestational diabetes mellitus (GDM), according to a study published online Oct. 4 in Diabetes Care.

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Calcium Supplements May Be Detrimental to Heart Health

WEDNESDAY, Oct. 12, 2016 (HealthDay News) -- Dietary calcium in the form of supplements, but not calcium-rich foods, might have a harmful impact on the heart, according to a study published online Oct. 11 in the Journal of the American Heart Association.

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Doctors Better Diagnosticians Than Symptom-Checker Programs

WEDNESDAY, Oct. 12, 2016 (HealthDay News) -- Physicians are twice as likely to get the right diagnosis on the first try as 23 popular symptom-checking computer programs, according to a research letter published online Oct. 11 in JAMA Internal Medicine.

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Low HDL-C, High TG Increase Risk for Diabetic Kidney Disease

WEDNESDAY, Oct. 12, 2016 (HealthDay News) -- For patients with diabetes, low high-density lipoprotein cholesterol (HDL-C) and high triglyceride (TG) levels are associated with increased risk of diabetic kidney disease (defined as low estimated glomerular filtration rate [eGFR], an eGFR reduction >30 percent, and/or albuminuria), according to a study published online Oct. 4 in Diabetes Care.

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Cortisol Mediates Benefit for Early Session Psychotherapy

WEDNESDAY, Oct. 12, 2016 (HealthDay News) -- For patients with panic disorder with agoraphobia, cortisol mediates the effect of the time of day on subsequent outcome, with greater clinical improvement seen for earlier exposure sessions, according to a study published in the December issue of Psychoneuroendocrinology.

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Trends in Dietary Supplement Use Among U.S. Adults Changing

TUESDAY, Oct. 11, 2016 (HealthDay News) -- Use of traditional multivitamins is decreasing among Americans, while supplements such as vitamin D, fish oil, and probiotics are becoming more popular, according to a study published in the Oct. 11 issue of the Journal of the American Medical Association.

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High-Protein Diet Doesn't Improve Insulin Sensitivity

TUESDAY, Oct. 11, 2016 (HealthDay News) -- Postmenopausal obese women who lose weight eating a high-protein diet may not experience any improvements in insulin sensitivity, according to a study published in the Oct. 11 issue of Cell Reports.

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Copay Assist Programs Creating Problems in Health Care Markets

TUESDAY, Oct. 11, 2016 (HealthDay News) -- Despite offering assistance to individuals who cannot afford expensive medications, copay assistance programs create broader problems in health care markets, according to an Ideas and Opinions piece published online Oct. 11 in the Annals of Internal Medicine.

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Genetic Increase in SBP Linked to Risk of Type 2 Diabetes

TUESDAY, Oct. 11, 2016 (HealthDay News) -- An increase in systolic blood pressure (SBP) due to genetic variants is associated with increased risk of type 2 diabetes, according to research published online Oct. 4 in Diabetes.

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U.S. Health Care System Is One of the Least Efficient Worldwide

MONDAY, Oct. 10, 2016 (HealthDay News) -- The U.S. health care system is one of the least efficient worldwide based on a Bloomberg index that assesses life expectancy, health care spending per capita, and relative spending as a share of gross domestic product, according to a report published by Bloomberg.

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Ghrelin May Predict Cognitive Impairment

MONDAY, Oct. 10, 2016 (HealthDay News) -- Blood levels of ghrelin may be a predictor of executive function impairment in patients with type 2 diabetes mellitus (T2DM), according to a study published online Sept. 30 in the Journal of Diabetes Investigation.

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Strategies Presented for Managing Physician Burnout

FRIDAY, Oct. 7, 2016 (HealthDay News) -- Effective strategies for managing physician burnout include mindfulness and stress-management training, according to a review published online Sept. 28 in The Lancet.

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Global Burden of Disease Report Evaluates the World's Health

FRIDAY, Oct. 7, 2016 (HealthDay News) -- The United States lags behind other advanced nations when it comes to infant mortality and the life expectancy of its citizens, according to a comprehensive review of global health statistics published in the Oct. 8 issue of The Lancet.

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Males Conceived Via ICSI May Have Sperm Abnormalities

FRIDAY, Oct. 7, 2016 (HealthDay News) -- Males who were conceived using intracytoplasmic sperm injection (ICSI) may have lower sperm quantity and quality than those conceived naturally, according to research published online Oct. 5 in Human Reproduction.

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Exposure to LDL-C-Lowering Genetic Variants Ups T2DM Risk

THURSDAY, Oct. 6, 2016 (HealthDay News) -- Low-density lipoprotein cholesterol (LDL-C)-lowering genetic variants are associated with increased risk of type 2 diabetes, according to a meta-analysis published in the Oct. 4 issue of the Journal of the American Medical Association.

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Industry-Funded Team Says Algorithm Improves HbA1c Value

THURSDAY, Oct. 6, 2016 (HealthDay News) -- Industry-funded researchers say they've developed a way to improve the accuracy of glycated hemoglobin (HbA1c) testing, according to a report published in the Oct. 5 issue of Science Translational Medicine.

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U.S. Smoking Rates Vary Across Counties Within States

WEDNESDAY, Oct. 5, 2016 (HealthDay News) -- Parts of the Midwest and South have the highest smoking rates in the United States, according to a study published online Oct. 1 in Cancer Epidemiology, Biomarkers & Prevention.

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No Evidence Activity Tracker Devices Raise Fitness Levels

WEDNESDAY, Oct. 5, 2016 (HealthDay News) -- There's no evidence that fitness tracking devices raise activity levels enough to improve health, even with financial rewards, according to a study published online Oct. 4 in The Lancet Diabetes & Endocrinology.

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Vitamin D Doesn't Improve Glucose Measures

WEDNESDAY, Oct. 5, 2016 (HealthDay News) -- Weekly doses of vitamin D do not improve oral glucose tolerance or markers of glycemic status among those at risk for diabetes, according to a study published online Sept. 26 in Diabetes, Obesity and Metabolism.

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Exenatide Does Not Promote Weight Loss in Schizophrenia

WEDNESDAY, Oct. 5, 2016 (HealthDay News) -- For antipsychotic-treated obese patients with schizophrenia, glucagon-like peptide-1 receptor agonists (GLP-1RAs) do not appear to promote weight loss, according to a study published online Sept. 26 in Diabetes, Obesity and Metabolism.

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More Evidence for Benefit of Reduced Salt Intake on Mortality

TUESDAY, Oct. 4, 2016 (HealthDay News) -- Sodium intake has a direct relationship with total mortality, according to a report published in the Oct. 11 issue of the Journal of the American College of Cardiology.

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Doctors Spending in Excess of $32,000 on Health IT

TUESDAY, Oct. 4, 2016 (HealthDay News) -- Doctors are spending more than $32,000 per year on health information technology (IT), according to an article published in Medical Economics.

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High Incidence of Cardiovascular Risk Factors in Older Adults

TUESDAY, Oct. 4, 2016 (HealthDay News) -- Older adults have high incidence of cardiovascular risk factors, with increased incidence of hypertension, diabetes mellitus, and dyslipidemia for blacks, according to a study published online Sept. 26 in the Journal of the American Geriatrics Society.

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Absent Pulses Up Risk of Major Vascular Outcomes in T2DM

TUESDAY, Oct. 4, 2016 (HealthDay News) -- For patients with type 2 diabetes, absent dorsalis pedis and/or posterior tibial pulses are associated with increased risk of major vascular outcomes, according to a study published online Sept. 27 in Diabetes Care.

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Summer Concentrations of 25OHD Predict Bone Mineral Density

TUESDAY, Oct. 4, 2016 (HealthDay News) -- Summer levels of serum 25-hydroxyvitamin D (S-25OHD) are associated with bone mineral density of the total hip, according to a study published online Sept. 25 in the Journal of Internal Medicine.

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New AMA Module Helps Identify Physician Distress

MONDAY, Oct. 3, 2016 (HealthDay News) -- A new resource has been developed to help physicians identify distressed colleagues and help them to access care, according to a report published by the American Medical Association (AMA).

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Researchers Question Value of Web-Based Test for Prediabetes

MONDAY, Oct. 3, 2016 (HealthDay News) -- A simple, seven-question test for prediabetes may be needlessly sending millions of healthy Americans to their physicians for follow-up testing, according to a research letter published online Oct. 3 in JAMA Internal Medicine.

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Physical Activity Reduces Intrahepatic Lipid Content

MONDAY, Oct. 3, 2016 (HealthDay News) -- For patients with nonalcoholic fatty liver disease (NAFLD) and underlying metabolic disorders, physical activity is associated with a reduction in intrahepatic lipid content and markers of hepatocellular injury, according to a meta-analysis published in the October issue of Clinical Gastroenterology and Hepatology.

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Increased Total, CVD Mortality in Young Adults With T1DM

MONDAY, Oct. 3, 2016 (HealthDay News) -- Young adults with long-standing, childhood-onset type 1 diabetes mellitus (T1DM) have increased total and cardiovascular disease (CVD) mortality, according to a study published online Sept. 21 in Diabetes Care.

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