Obstructive Sleep Apnea Linked to Thinning of Calvaria, Skull Base

Share this content:
Obstructive Sleep Apnea Linked to Thinning of Calvaria, Skull Base
Obstructive Sleep Apnea Linked to Thinning of Calvaria, Skull Base

FRIDAY, May 4, 2018 (HealthDay News) -- Obstructive sleep apnea (OSA) is associated with thinning of the calvaria and skull base, according to a study published online May 3 in JAMA Otolaryngology-Head & Neck Surgery.

Cyrus Rabbani, M.D., from Indiana University School of Medicine in Indianapolis, and colleagues conducted a retrospective cohort study of 1,012 patients who underwent a polysomnogram and had high-resolution computed tomographic imaging of the head. Patients with and without OSA (56 and 58 patients, respectively) were matched for age and body mass index.

The researchers found that patients with OSA had thinner mean calvaria (2.73 versus 2.47 mm; difference, −0.26 mm [95 percent confidence interval, −0.49 to −0.04]) and thinner skull bases (5.03 versus 4.32 mm; difference, −0.71 mm [95 percent confidence interval, −1.23 to −0.19]). The mean extracranial zygoma thickness was the same for those with and without OSA (4.92 versus 4.84 mm; difference, −0.07 mm; 95 percent confidence interval, −0.39 to 0.24). In nearly twice as many patients with versus without OSA, the tegmen mastoideum was dehiscent (37 versus 20 percent; difference, 17 percent; 95 percent confidence interval, 0.4 to 32).

"OSA was independently associated with intracranial bone (calvaria and skull base) thinning and not with extracranial (zygoma) thinning," the authors write. "These findings support a possible role of OSA in the pathophysiologic development of spontaneous cerebrospinal fluid leaks."

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters


More in Home

Social, Communication Delays With False-Negative on M-CHAT

Social, Communication Delays With False-Negative on M-CHAT

Delays for those who pass M-CHAT screening at 18 months but are later diagnosed with ASD

FDA Approves Aimovig to Prevent Migraines

FDA Approves Aimovig to Prevent Migraines

Patients taking Aimovig reported one to two fewer monthly migraine days than those taking pacebo

Risk of Dementia Up for Older Adults With Lowest Wealth

Risk of Dementia Up for Older Adults With ...

Increased risk seen independent of education, index of multiple deprivation, health indicators

is free, fast, and customized just for you!

Already a member?

Sign In Now »