Nutrigenetic-Based Diet Doesn't Increase Weight Loss

This article originally appeared here.
Share this content:
Nutrigenetic-Based Diet Doesn't Increase Weight Loss
Nutrigenetic-Based Diet Doesn't Increase Weight Loss

MONDAY, Oct. 5, 2015 (HealthDay News) -- A nutrigenetic-based diet does not increase weight loss, compared with a standard balanced diet, according to a study published in the September issue of Clinical Gastroenterology and Hepatology.

Karen A. Frankwich, M.D., from the University of California, San Diego, and colleagues prospectively studied 51 obese or overweight U.S. veterans on an established weight management program (the MOVE! program). Participants were randomly assigned to a nutrigenetic-guided diet (balanced, low-carbohydrate, low-fat, or Mediterranean; 30 patients; based on results from the Pathway FIT test) or a standard balanced diet (21 patients).

The researchers observed no significant difference between the groups in the percentage of participants who lost 5 percent of their body weight at eight weeks (35.0 percent on the balanced diet and 26.9 percent on the nutrigenetic-guided diet). Adherence to the diets was challenging in both groups. However, for the nutrigenetic-guided diet, adherence correlated with weight loss; this was not the case for the standard therapy group. At eight weeks, the most weight was lost by participants who had low-risk polymorphisms for obesity (5.0 percent, versus 2.9 percent among all other participants; P = 0.02). They also had significantly greater reductions in body mass index (6.4 versus 3.6 percent; P = 0.03) and waist circumference (6.5 versus 2.6 percent; P = 0.02) at 24 weeks.

"Genetic features can identify individuals most likely to benefit from a balanced diet weight loss strategy," the authors write.

Several authors disclosed financial ties to Pathway Genomics, which funded the study.

Abstract
Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease


More in Home

FDA Approves 'Artificial Pancreas' for Type 1 Diabetes

FDA Approves 'Artificial Pancreas' for Type 1 Diabetes

MiniMed 670G hybrid closed loop system automatically monitors glucose, delivers insulin

More Evidence HPV Vaccine Protects Against Cervical Cancer

More Evidence HPV Vaccine Protects Against Cervical Cancer

Protection appears to occur even when only one or two of the recommended doses are given

Prescribed NSAIDs Tied to Higher Heart Failure Risk

Prescribed NSAIDs Tied to Higher Heart Failure Risk

Study of millions of health records suggests an association

is free, fast, and customized just for you!

Already a member?

Sign In Now »