NSAID Use Linked to A-Fib Risk in Middle-Aged Asian Population

Share this content:
NSAID Use Linked to A-Fib Risk in Middle-Aged Asian Population
NSAID Use Linked to A-Fib Risk in Middle-Aged Asian Population

FRIDAY, March 23, 2018 (HealthDay News) -- Nonsteroidal anti-inflammatory drug (NSAID) use is associated with increased risk of atrial fibrillation (AF) in a middle-aged Asian population, according to a study published online March 20 in the British Journal of Clinical Pharmacy.

Shao-Yuan Chuang, Ph.D., from the National Health Research Institutes in Taiwan, and colleagues conducted a nested case-control study to examine the correlation between NSAID use and the risk of AF in a middle-aged Asian population using the National Health Insurance Research Database (NHIRD) in Taiwan. Cases with a diagnosis of AF were identified and matched with controls from three independent Longitudinal Health Insurance Databases derived from the NHIRD. Data were included from 28,529 cases and 28,529 matched controls.

The researchers found that, compared with non-users, NSAID users had increased AF risk (adjusted odds ratio, 1.18). On examination of the effects of different classes of NSAID on AF risk, participants who used non-selective NSAIDs and those with a combined use of selective and non-selective NSAIDs had a significantly elevated risk of AF (adjusted odds ratios, 1.18 and 1.3, respectively).

"NSAID use was associated with an increased risk of AF occurrence among the participants included in our study cohort," the authors write. "Closely monitoring the adverse effects of NSAID treatment on the risk of AF will be important, particularly among individuals at high risk."

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters


More in Home

CDC: Birth Rate for 10- to-14-Year-Olds at Record Low in 2016

CDC: Birth Rate for 10- to-14-Year-Olds at Record ...

Reduction in birth rates for all race and Hispanic origin groups; largest decline in non-Hispanic blacks

Lonafarnib May Lower Mortality in Hutchinson-Gilford Progeria

Lonafarnib May Lower Mortality in Hutchinson-Gilford Progeria

Lower mortality seen with lonafarnib monotherapy after 2.2 years compared with no treatment

About 40 Percent of Men Report Experiencing Weight Stigma

About 40 Percent of Men Report Experiencing Weight ...

Experience of weight stigma associated with increased odds of underweight or obesity

is free, fast, and customized just for you!

Already a member?

Sign In Now »