November 2017 Briefing - Diabetes & Endocrinology

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for November 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Severe Hypoglycemia a Potent Marker of Cardiovascular Risk

THURSDAY, Nov. 30, 2017 (HealthDay News) -- Among patients with diabetes, severe hypoglycemia is associated with high absolute risk of cardiovascular events and mortality, according to a study published online Nov. 10 in Diabetes Care.

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Mean Serum Allopregnanolone Low Across Weight Extremes

THURSDAY, Nov. 30, 2017 (HealthDay News) -- Women at both extremes of the weight spectrum have low mean serum allopregnanolone, which has been linked to increased depression and anxiety severity, according to a study published online Nov. 1 in Neuropsychopharmacology.

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More Than Half Today's Children Expected to Be Obese at 35

THURSDAY, Nov. 30, 2017 (HealthDay News) -- More than half of today's children are expected to be obese at the age of 35 years, with about half of the prevalence occurring during childhood, according to a study published in the Nov. 30 issue of the New England Journal of Medicine.

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Evidence Lacking for Prenatal Vitamin D Supplementation

THURSDAY, Nov. 30, 2017 (HealthDay News) -- Prenatal vitamin D supplementation during pregnancy may have some benefits, although the evidence is low quality, according to research published online Nov. 29 in The BMJ.

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Many Seniors Have Not Discussed Avoiding Drug Interactions

WEDNESDAY, Nov. 29, 2017 (HealthDay News) -- Older adults report feeling confident that they know how to avoid drug interactions despite only 35 percent having spoken to someone about it in the past year, according to findings from the National Poll on Healthy Aging, published online Nov. 29.

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Unapproved Drugs Identified in Androgen Receptor Modulators

WEDNESDAY, Nov. 29, 2017 (HealthDay News) -- Products marketed as selective androgen receptor modulators and sold via the internet frequently contain unapproved drugs and substances, and the amount of active compound often does not match that listed on the label, according to a study published in the Nov. 28 issue of the Journal of the American Medical Association.

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Over 5 Percent of Incident Cancer Due to Diabetes, High BMI

WEDNESDAY, Nov. 29, 2017 (HealthDay News) -- More than 5 percent of all incident cancers in 2012 were attributable to diabetes and high body mass index (BMI), according to a study published online Nov. 28 in The Lancet Diabetes & Endocrinology.

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Endocrine-Disrupting Chemicals Linked to Diabetes Disparities

WEDNESDAY, Nov. 29, 2017 (HealthDay News) -- Disparities in exposure to diabetes-associated environmental endocrine-disrupting chemicals (EDCs) may contribute to disparities in diabetes, according to a review published online Nov. 15 in Diabetes Care.

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Clinician Denial of Patient Requests Impacts Satisfaction

TUESDAY, Nov. 28, 2017 (HealthDay News) -- Clinician denial of some types of tests requested by patients is associated with worse patient satisfaction with the clinician, according to a study published online Nov. 27 in JAMA Internal Medicine.

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Value-Based Payment Modifier Not Tied to Practice Performance

TUESDAY, Nov. 28, 2017 (HealthDay News) -- The Value-Based Payment Modifier (VM) is not associated with performance differences between practices serving higher-risk and lower-risk patients, according to a study published online Nov. 28 in the Annals of Internal Medicine.

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1998 to 2014 Saw Drop in CVD Hospitalization Rates in Diabetes

TUESDAY, Nov. 28, 2017 (HealthDay News) -- Cardiovascular disease (CVD) hospitalization rates have declined in recent years among individuals with and those without diabetes, according to a study published online Nov. 17 in Diabetes Care.

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Essay Adds to Discourse on Impact of Suggestive Jokes

MONDAY, Nov. 27, 2017 (HealthDay News) -- Seemingly benign, recurring patterns of joking around a single theme (joke cycles) can contribute to humorizing and legitimizing sexual misconduct, according to an essay published online Nov. 12 in Communication and Critical/Cultural Studies.

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New Workflows Have Potential to Address Provider Burnout

MONDAY, Nov. 27, 2017 (HealthDay News) -- New solutions are needed to address burnout among health care team members, yet, in a catch-22 situation for health industry leaders, change fatigue contributes to burnout, according to a Vocera Communications report entitled In Pursuit of Resilience, Well-Being, and Joy in Healthcare.

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Genetic Variants Tied to Type 1 Diabetes Heterogeneity

MONDAY, Nov. 27, 2017 (HealthDay News) -- Transcription factor 7 like 2 (TCF7L2) genetic variants contribute to phenotypic heterogeneity of type 1 diabetes, according to a study published online Oct. 12 in Diabetes Care.

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Coffee Consumption Appears to Provide More Benefit Than Harm

MONDAY, Nov. 27, 2017 (HealthDay News) -- Coffee consumption seems safe and is associated with reduced risk for various health outcomes, according to a review published online Nov. 22 in The BMJ.

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Cinnamon Shows Potential As Tool in Fight Against Obesity

MONDAY, Nov. 27, 2017 (HealthDay News) -- The compound cinnamaldehyde (CA), found in cinnamon, activates fat cells to start burning energy in both mice and humans, according to a study published in the December issue of Metabolism.

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Female Physicians' Spouses More Likely to Work

WEDNESDAY, Nov. 22, 2017 (HealthDay News) -- Spouses of female physicians are on average more educated and work more hours outside the home than spouses of male physicians, according to a research letter published online Nov. 21 in the Annals of Internal Medicine.

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Maternal GDM Tied to Child's Cardiometabolic Profile

WEDNESDAY, Nov. 22, 2017 (HealthDay News) -- Teenage offspring of mothers with gestational diabetes mellitus (GDM) have increased adiposity and an adverse cardiometabolic profile, according to a study published online Oct. 16 in Diabetes Care.

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High Costs Associated With Physician Burnout, Attrition

TUESDAY, Nov. 21, 2017 (HealthDay News) -- Physicians who are experiencing burnout are more than twice as likely to leave their organization within two years, and this is associated with significant economic costs, according to a report from the American Medical Association.

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Insulin Doesn't Prevent Diabetes in Relatives of T1DM Patients

TUESDAY, Nov. 21, 2017 (HealthDay News) -- Oral insulin does not delay onset of type 1 diabetes in autoantibody-positive relatives of patients with type 1 diabetes, according to a study published in the Nov. 21 issue of the Journal of the American Medical Association.

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NOACs Show Lower Risk of Adverse Renal Outcomes in A-Fib

TUESDAY, Nov. 21, 2017 (HealthDay News) -- For patients with atrial fibrillation (AF), non-vitamin K antagonist oral anticoagulants (NOACs) are associated with lower risks of adverse renal outcomes than warfarin, according to a study published in the Nov. 28 issue of the Journal of the American College of Cardiology.

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Few U.S. Adults Meet Fruit, Veg Intake Recommendations

TUESDAY, Nov. 21, 2017 (HealthDay News) -- Across all 50 states and the District of Columbia (D.C.), few adults consume the recommended amount of fruits and vegetables, according to research published in the Nov. 17 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Higher β-Blocker Dose Linked to Lower Mortality Risk

TUESDAY, Nov. 21, 2017 (HealthDay News) -- An increased β-blocker dose is associated with a greater prognostic advantage in patients with chronic heart failure (CHF) and diabetes than in those with CHF but no diabetes, according to a study published online Oct. 25 in Diabetes Care.

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Brain Glucose Responses Diminish With Diabetes, Obesity

MONDAY, Nov. 20, 2017 (HealthDay News) -- The rise of brain glucose levels is blunted during hyperglycemia in adults with obesity and type 2 diabetes mellitus (T2DM), according to a study published online Oct. 19 in JCI Insight.

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Chronic Conditions Increasing Among Childbearing Women

MONDAY, Nov. 20, 2017 (HealthDay News) -- Between 2005 and 2014, the prevalence of chronic conditions increased across all segments of the childbearing population, according to a study published online Nov. 7 in Obstetrics & Gynecology.

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Fat Distribution May Influence Bone Strength in Adolescence

MONDAY, Nov. 20, 2017 (HealthDay News) -- Visceral adipose tissue (VAT) in girls and central adiposity in boys play a role in the acquisition of bone strength during adolescence, according to a study published online Oct. 30 in the Journal of Bone and Mineral Research.

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Spinal Cord Stimulation May Reduce Neuropathic Pain

MONDAY, Nov. 20, 2017 (HealthDay News) -- Spinal cord stimulation (SCS) effectively reduces chronic pain symptoms in individuals with painful diabetic polyneuropathy (PDPN), according to a study published online Nov. 6 in Diabetes Care.

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Attributes of High-Value Primary Care Identified

MONDAY, Nov. 20, 2017 (HealthDay News) -- Six statistically significant attributes of high-value primary care have been identified, and they include decision support for evidence-based medicine, risk-stratified care management, and coordination of care, according to a study published in the November/December issue of the Annals of Family Medicine.

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SMS Reminders Moderately Effective for Flu Vaccination

MONDAY, Nov. 20, 2017 (HealthDay News) -- Short message service (SMS) reminders are a moderately effective way to increase the rate of influenza vaccination among high-risk patients, according to a study published in the November/December issue of the Annals of Family Medicine.

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Many Health Care Providers Work While Sick

FRIDAY, Nov. 17, 2017 (HealthDay News) -- More than 40 percent of health care personnel (HCP) with influenza-like illness (ILI) work while ill, according to a study published in the November issue of the American Journal of Infection Control.

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Intensive BP Control Lacks Benefit in Chronic Kidney Disease

FRIDAY, Nov. 17, 2017 (HealthDay News) -- Intensive blood pressure (BP) control may provide no benefit and may even be harmful for patients with moderate-to-advanced chronic kidney disease, according to a study published online Oct. 16 in the Journal of Internal Medicine.

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Simple Checklist Can Identify Useful Clinical Practice Guidelines

FRIDAY, Nov. 17, 2017 (HealthDay News) -- A simple, easy-to-use checklist, the Guideline Trustworthiness, Relevance, and Utility Scoring Tool (G-TRUST), can identify useful clinical practice guidelines, according to a study published in the September/October issue of the Annals of Family Medicine.

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First-Line Metformin Use for DM Up; Sulfonylurea Use Down

FRIDAY, Nov. 17, 2017 (HealthDay News) -- Among patients with type 2 diabetes initiating antidiabetes drugs (ADDs), first-line use of metformin has increased since 2005, while sulfonylureas have remained the most popular second-line agent, according to a study published online Nov. 6 in Diabetes Care.

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Risk of Falls Up With Mild, Moderate Diabetic Retinopathy

FRIDAY, Nov. 17, 2017 (HealthDay News) -- Among Asians, individuals with mild and moderate diabetic retinopathy (DR) are more likely to have fallen, and greater perceived barriers to diabetes self-management (DSM) are associated with the severity of DR, according to two studies published online Nov. 16 in JAMA Ophthalmology.

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Docs' Preparedness Influences Exercise Recommendations

FRIDAY, Nov. 17, 2017 (HealthDay News) -- Primary care providers who feel prepared are more likely to recommend physical activity to patients with disabilities, according to a study published online Nov. 16 in Preventing Chronic Disease.

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Vitamin D Tied to Better Assisted Reproductive Therapy Outcomes

THURSDAY, Nov. 16, 2017 (HealthDay News) -- For women undergoing assisted reproductive treatment (ART), those who are replete in vitamin D have better outcomes, including live birth, a positive pregnancy test, and clinical pregnancy, according to a review published online Nov. 14 in Human Reproduction.

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In 2007-2014, Glycemic Control Plateaued in Diabetes Patients

WEDNESDAY, Nov. 15, 2017 (HealthDay News) -- Despite increases in HbA1c testing and awareness, glycemic control seems to have plateaued among patients with diabetes between 2007 and 2014, according to a research letter published online Nov. 14 in the Journal of the American Medical Association.

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ER- Breast CA Risk Up for African-Americans With T2DM

WEDNESDAY, Nov. 15, 2017 (HealthDay News) -- African-American (AA) women with type 2 diabetes (T2D) appear to be at increased risk of developing estrogen receptor-negative (ER-) breast cancer, with the highest risk among nonobese individuals, according to a study published online Nov. 15 in Cancer Research.

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Health Care Experts in Favor of Patient Contribution to Notes

WEDNESDAY, Nov. 15, 2017 (HealthDay News) -- Health care experts are supportive of OurNotes, an intervention in which patients and families co-produce medical notes with clinicians, according to a research letter published online Nov. 13 in the Annals of Internal Medicine.

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Eating More Nuts Associated With Lower Heart Disease Risk

TUESDAY, Nov. 14, 2017 (HealthDay News) -- Nut consumption is tied to a decreased risk of cardiovascular disease and coronary heart disease (CHD), according to a study published online Nov. 13 in the Journal of the American College of Cardiology.

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Leisure Time Exercise Linked to Reduced Mortality in T1DM

TUESDAY, Nov. 14, 2017 (HealthDay News) -- For patients with type 1 diabetes, including those with chronic kidney disease (CKD), leisure-time physical activity (LTPA) is associated with reduced risk of all-cause mortality, according to a study published online Oct. 16 in Diabetes Care.

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About 20 Percent of U.S. Adults Currently Use Tobacco Products

MONDAY, Nov. 13, 2017 (HealthDay News) -- About one in five U.S. adults currently uses any tobacco product, according to a study published online Nov. 9 in Morbidity and Mortality Weekly Report.

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Risk of End-Stage Renal Disease Low With Type 1 Diabetes

THURSDAY, Nov. 9, 2017 (HealthDay News) -- Among patients with childhood-onset type 1 diabetes, there is a very low incidence of end-stage renal disease (ESRD), according to a Norwegian study published online October 12 in Diabetes Care.

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Doctors Have Extra Two Weeks to Preview Performance Data

WEDNESDAY, Nov. 8, 2017 (HealthDay News) -- Physicians have two extra weeks to preview their 2016 performance information as a result of a mistake related to the Centers for Medicare & Medicaid Services' Physician Compare online resource, according to a report published by the American Academy of Family Physicians.

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Drop in Incidence of End-Stage Renal Disease Due to Diabetes

WEDNESDAY, Nov. 8, 2017 (HealthDay News) -- The incidence of end-stage renal disease (ESRD) with diabetes listed as the primary cause (ESRD-D) decreased across the United States from 2000 to 2014, according to a study published online Nov. 2 in Morbidity and Mortality Weekly Report.

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Increases in U.S. Health Spending Tied to Health Service Price

WEDNESDAY, Nov. 8, 2017 (HealthDay News) -- Factors including increases in health care service price and intensity are associated with increases in U.S. health care spending from 1996 to 2013, according to a study published online Nov. 7 in the Journal of the American Medical Association.

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Intensity of Exercise Affects Impact on Mortality Risk

TUESDAY, Nov. 7, 2017 (HealthDay News) -- Total physical activity (PA) and moderate- to vigorous-intensity PA (MVPA) are inversely associated with mortality, though light-intensity PA and sedentary behavior are not associated with mortality, according to a research letter published online Nov. 6 in Circulation.

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Lifestyle Changes Successfully Reduce Incidence of Diabetes

TUESDAY, Nov. 7, 2017 (HealthDay News) -- Lifestyle modification (LSM) and medications can reduce the incidence of diabetes in adults at risk, although the effects of medications are short-lived, according to a review published online Nov. 6 in JAMA Internal Medicine.

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Novel Method Developed for Estimating Prevalence of Diabetes

MONDAY, Nov. 6, 2017 (HealthDay News) -- A novel method has been developed to enhance the prevalence estimates of diabetes and prediabetes, according to a study published online Nov. 2 in Preventing Chronic Diseases.

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Postmenopausal Estradiol Linked to Blunted Cortisol Responses

THURSDAY, Nov. 2, 2017 (HealthDay News) -- Postmenopausal estradiol therapy (ET) may protect certain types of cognition in the presence of stress, according to a study published online Nov. 2 in the Journal of Clinical Endocrinology & Metabolism.

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Novel Artificial Pancreas Cuts HbA1c, Hypoglycemia in T1DM

FRIDAY, Nov. 3, 2017 (HealthDay News) -- A novel adaptive artificial pancreas (AP) can reduce hemoglobin A1c (HbA1c) in adults with type 1 diabetes (T1D), according to a study published online Oct. 13 in Diabetes Care.

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Pricing Interventions Increase Sales, Intake of Healthy Foods

FRIDAY, Nov. 3, 2017 (HealthDay News) -- Pricing interventions seem to improve access to healthy food and beverage options with increases in stocking and sales of these items, according to a review published online Nov. 2 in Preventing Chronic Disease.

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GLP-1 May Mediate Effects of Gastric Bypass on CNS Activation

THURSDAY, Nov. 2, 2017 (HealthDay News) -- The central effects of glucagon-like peptide-1 (GLP-1) may mediate the effects of Roux-en-Y gastric bypass (RYGB) on central nervous system (CNS) activation in response to visual and gustatory food cues, according to a study published online Oct. 12 in Diabetes Care.

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Driving Impairment Warnings Often Not Given With Rx Meds

THURSDAY, Nov. 2, 2017 (HealthDay News) -- Not all prescription drug users report receiving warnings about driving impairment, according to a study published online Nov. 1 in the Journal of Studies on Alcohol and Drugs.

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ACE Inhibitor, Statin No Benefit for T1DM, High Albumin Excretion

THURSDAY, Nov. 2, 2017 (HealthDay News) -- For adolescents with type 1 diabetes and high levels of albumin excretion, neither angiotensin-converting-enzyme (ACE) inhibitors nor statins change the albumin-to-creatinine ratio over time, according to a study published online Nov. 1 in the New England Journal of Medicine.

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CMS Launches Initiative to Examine Impact of Regulations

WEDNESDAY, Nov. 1, 2017 (HealthDay News) -- The Centers for Medicare & Medicaid Services (CMS) has launched an initiative to examine which provider regulations should be discarded or revamped amid concerns that the regulations are reducing the amount of time that physicians spend with patients, according to an article published in Modern Healthcare.

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Magnesium, T2DM Link Seen in Poor-Carbohydrate-Quality Diet

WEDNESDAY, Nov. 1, 2017 (HealthDay News) -- The correlation between higher magnesium intake and reduced risk of type 2 diabetes is stronger in the context of poor-carbohydrate-quality diets, according to a study published online Oct. 4 in Diabetes Care.

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