November 2016 Briefing - Cardiology

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Here are what the editors at HealthDay consider to be the most important developments in Cardiology for November 2016. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Levels of Total, LDL Cholesterol Continue to Fall in the U.S.

WEDNESDAY, Nov. 30, 2016 (HealthDay News) -- Healthier diets may be a factor in the ongoing decline in cholesterol levels for Americans, according to a research letter published online Nov. 30 in JAMA Cardiology.

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Heart-Healthy Habits Should Also Be Promoted to Low-Risk Patients

WEDNESDAY, Nov. 30, 2016 (HealthDay News) -- Primary care doctors should offer counseling about healthy lifestyle habits to prevent heart disease even to adults who have a low or average risk of developing cardiovascular disease, the U.S. Preventive Services Task Force advises.

Evidence Review
Draft Recommendation Statement
Comment on Recommendation

Highest Increase in Acute STEMI Risk for Youngest Smokers

WEDNESDAY, Nov. 30, 2016 (HealthDay News) -- Smoking is associated with an increased risk of acute ST-segment elevation myocardial infarction (STEMI), with the most pronounced increase among younger smokers, according to a study published online Nov. 29 in Heart.

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Amyloid Beta Deposits Can Affect Hearts of Alzheimer's Patients

TUESDAY, Nov. 29, 2016 (HealthDay News) -- Amyloid beta (Aβ) deposits in Alzheimer's patients might also negatively affect their heart muscle and increase their risk of heart failure, according to a study published in the Dec. 6 issue of the Journal of the American College of Cardiology.

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Three Factors Weigh Heavy in Risk of Heart Failure

TUESDAY, Nov. 29, 2016 (HealthDay News) -- Middle-aged adults who've avoided obesity, hypertension, and diabetes are far less likely than others to develop heart failure in their later years, according to research published in the Dec. 1 issue of JACC: Heart Failure.

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Review Links Natriuretic Peptide Thresholds to Mortality in ADHF

TUESDAY, Nov. 29, 2016 (HealthDay News) -- For patients hospitalized with acute decompensated heart failure (ADHF), achieving predischarge natriuretic peptide (NP) thresholds is associated with reduced mortality and readmission, according to a review published online Nov. 29 in the Annals of Internal Medicine.

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Improved Cognitive Status Seen Following TAVR

TUESDAY, Nov. 29, 2016 (HealthDay News) -- Transcatheter aortic valve replacement (TAVR) is associated with global improvement in cognitive status, according to a study published in the Nov. 15 issue of the Journal of the American College of Cardiology.

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Significant Birth Cohort Effect in Ischemic Stroke Risk

MONDAY, Nov. 28, 2016 (HealthDay News) -- Birth cohort seems to affect the risk of ischemic stroke, with lower age-adjusted rates for those born from 1945 to 1954 versus those born in earlier and later years, according to a study published online Nov. 23 in the Journal of the American Heart Association.

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Survey IDs Factors Influencing Physician Recruitment

WEDNESDAY, Nov. 23, 2016 (HealthDay News) -- Factors that influence whether an internal medicine physician will accept a position include opportunities for improved work-life balance as well as compensation, according to an article published in Medical Economics.

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Many Nursing Home Residents Not Taking β-Blockers After AMI

WEDNESDAY, Nov. 23, 2016 (HealthDay News) -- Many nursing home (NH) residents do not initiate beta-blocker use after acute myocardial infarction (AMI), according to a study published online Nov. 15 in the Journal of the American Geriatrics Society.

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Four ER Visits for Adverse Drug Events Per 1,000 People

TUESDAY, Nov. 22, 2016 (HealthDay News) -- In 2013 to 2014, the estimated prevalence of emergency department visits for adverse drug events was four per 1,000 individuals, according to research published in the Nov. 22 issue of the Journal of the American Medical Association.

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Rising Rx, ER Prices Pushing U.S. Health Care Spending Up

TUESDAY, Nov. 22, 2016 (HealthDay News) -- Privately insured Americans spent nearly 5 percent more on health care last year than in 2014; this increase was significantly more than that seen in previous years and reflects higher costs for prescription drugs, emergency department visits, and hospitalizations, according to a report published Nov. 22 by the Health Care Cost Institute.

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Beta-Blocker Tx Attenuates Prognostic Value of ppMHR

TUESDAY, Nov. 22, 2016 (HealthDay News) -- The prognostic value of lower heart rate thresholds (defined as the percentage of age-predicted maximal heart rate achieved, or ppMHR) is attenuated for patients on beta-blocker therapy (BBT), according to a study published in the Dec. 1 issue of The American Journal of Cardiology.

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Thiazide-Type Diuretic Treatment Tied to Lower Fracture Risk

MONDAY, Nov. 21, 2016 (HealthDay News) -- Thiazide-type diuretic therapy reduces hip and pelvic fracture risk compared with other antihypertensive medication therapy, according to a study published online Nov. 21 in JAMA Internal Medicine.

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Hemorrhage Risk Up in A-Fib Patients on Dabigatran, Statins

MONDAY, Nov. 21, 2016 (HealthDay News) -- Combining dabigatran with certain statin medications could raise the odds for major hemorrhage in patients with atrial fibrillation, according to a study published online Nov. 21 in CMAJ, the journal of the Canadian Medical Association.

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Local Anesthetic As Safe As General Anesthetic for TAVR

MONDAY, Nov. 21, 2016 (HealthDay News) -- For patients undergoing transcatheter aortic valve replacement (TAVR), local anesthetic (LA) is as safe as general anesthetic (GA), with shorter procedure time and number of days in the hospital, according to a study published in the Dec. 1 issue of The American Journal of Cardiology.

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Smart Skin Patch Can Monitor Body Function Acoustically

THURSDAY, Nov. 17, 2016 (HealthDay News) -- A new type of acoustic sensor that resembles a small Band-Aid on the skin can monitor heartbeat and other health measures, according to a study published online Nov. 16 in Science Advances.

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CDC: Heart Disease Still Leading Cause of Death

THURSDAY, Nov. 17, 2016 (HealthDay News) -- Heart disease continues to top the list of likely cause of death among Americans, according to research published in the Nov. 18 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Competing Risks Influence Warfarin, Thromboembolism Link

THURSDAY, Nov. 17, 2016 (HealthDay News) -- For patients with nonvalvular atrial fibrillation, warfarin is associated with a reduction in thromboembolism, although the correlation is attenuated after accounting for competing death events, according to a study published online Nov. 12 in the Journal of the American Geriatrics Society.

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Data From Clinical Registries Can ID Novel Drug Interactions

THURSDAY, Nov. 17, 2016 (HealthDay News) -- Data mining can be used to discover unknown drug-drug interactions in cardiovascular medicine, according to a study published online Nov. 8 in Circulation: Cardiovascular Quality and Outcomes.

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Sodium Bicarbonate Prophylaxis Linked to Lower Mortality

THURSDAY, Nov. 17, 2016 (HealthDay News) -- For patients undergoing coronary angiography, sodium bicarbonate prophylaxis for contrast-associated nephropathy (CAN) is associated with reduced long-term mortality, according to research published in the Nov. 15 issue of The American Journal of Cardiology.

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Medication Adherence Up in Patient-Centered Medical Homes

WEDNESDAY, Nov. 16, 2016 (HealthDay News) -- Medication adherence is increased with receipt of care in a patient-centered medical home, according to a study published online Nov. 15 in the Annals of Internal Medicine.

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CHD Rates Down 20 Percent Since 1980s in the United States

MONDAY, Nov. 14, 2016 (HealthDay News) -- Cases of coronary heart disease (CHD) have dropped 20 percent in the United States over the last four decades, according to a research letter published in the Nov. 15 issue of the Journal of the American Medical Association, a theme issue on statins.

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Guidelines Updated for Management of PAD

MONDAY, Nov. 14, 2016 (HealthDay News) -- In a Clinical Practice Guideline published online Nov. 13 in Circulation, evidence-based recommendations are presented for the management of peripheral artery disease (PAD), focusing on lifestyle modification as well as medical treatment.

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USPSTF Advises Statins for Some Adults With No CVD History

MONDAY, Nov. 14, 2016 (HealthDay News) -- The U.S. Preventive Services Task Force (USPSTF) recommends that certain adults aged 40 to 75 years without cardiovascular disease (CVD) history but with one or more cardiovascular risk factors initiate statins. These recommendations are included in the final recommendation statement published in the Nov. 15 issue of the Journal of the American Medical Association, a theme issue on statins.

Recommendation Statement
Evidence Report

Women With GDM Have Elevated Risk of Future Cardiac Events

FRIDAY, Nov. 11, 2016 (HealthDay News) -- The risk of cardiovascular outcomes is elevated for women with gestational diabetes mellitus (GDM), even in the absence of subsequent type 2 diabetes mellitus (T2DM), according to a study published online Nov. 7 in Diabetes Care.

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CDC: Tobacco-Linked Cancers Make Up 40 Percent of All Cancers

FRIDAY, Nov. 11, 2016 (HealthDay News) -- Although rates of smoking in the United States have declined to new lows, health officials still estimate that four out of every 10 cancers is linked to the habit.

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HR Capabilities Positively Linked to Quality of Patient Care

FRIDAY, Nov. 11, 2016 (HealthDay News) -- Human resource (HR) capabilities are positively associated with quality of patient care, with the relationship mediated by proactive work, according to a study published recently in Human Resource Management.

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Modeling IDs Amount, Type of Data to Predict Heart Failure

FRIDAY, Nov. 11, 2016 (HealthDay News) -- Modeling has identified the amount and type of data needed to detect prediagnostic heart failure, according to research published online Nov. 8 in Circulation: Cardiovascular Quality and Outcomes.

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High-Intensity Statins Tied to Better Survival in CVD Patients

THURSDAY, Nov. 10, 2016 (HealthDay News) -- There is a graded association between intensity of statin therapy and mortality for patients with established atherosclerotic cardiovascular disease, according to research published online Nov. 9 in JAMA Cardiology.

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Ethnic Differences in Proximal Aortic Pulse Wave Velocity

THURSDAY, Nov. 10, 2016 (HealthDay News) -- Blacks and Hispanics have increased proximal aortic pulse wave velocity (PWV) and characteristic impedance (Zc) compared with whites, according to a study published online Nov. 9 in JACC: Cardiovascular Imaging.

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Reduced CD34+ Stem Cells Predicts CV Outcome in T2DM

THURSDAY, Nov. 10, 2016 (HealthDay News) -- Reduced baseline levels of circulating CD34+ stem cells predict adverse cardiovascular outcomes for patients with type 2 diabetes, according to a study published online Nov. 4 in Diabetes Care.

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Lipid-Rich Necrotic Core in Femoral Artery Ups PAD Events

WEDNESDAY, Nov. 9, 2016 (HealthDay News) -- Lipid-rich necrotic core (LRNC) in the proximal superficial femoral artery (SFA) is associated with higher rates of peripheral artery disease (PAD) events, according to a study published online Nov. 9 in JACC: Cardiovascular Imaging.

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Survival Lower for Night CPR Events in Children

WEDNESDAY, Nov. 9, 2016 (HealthDay News) -- Hospitalized children have reduced survival odds with cardiopulmonary resuscitation (CPR) events occurring at night compared to other times of the day, according to a study published online Nov. 7 in JAMA Pediatrics.

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Better Teamwork Linked to Improved Outcomes for CABG

WEDNESDAY, Nov. 9, 2016 (HealthDay News) -- For patients undergoing coronary artery bypass grafting (CABG), surgical outcomes are better for health systems with physicians who have higher teamwork levels, according to a study published online Nov. 8 in Circulation: Cardiovascular Quality and Outcomes.

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Anakinra Cuts Risk of Recurrence in Recurrent Pericarditis

WEDNESDAY, Nov. 9, 2016 (HealthDay News) -- Use of anakinra reduces the risk of recurrence of pericarditis among patients with recurrent pericarditis with colchicine resistance and corticosteroid dependence, according to a study published in the Nov. 8 issue of the Journal of the American Medical Association.

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Coronary Angiography, PCI Don't Impact Cognitive Function

TUESDAY, Nov. 8, 2016 (HealthDay News) -- There is no indication of postprocedural cognitive impairment for patients undergoing coronary angiography (CA) or percutaneous coronary intervention (PCI), according to a study published in the Nov. 15 issue of The American Journal of Cardiology.

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Probable Interaction ID'd for PrOD, Ribavirin With Warfarin

TUESDAY, Nov. 8, 2016 (HealthDay News) -- There is a probable interaction between paritaprevir/ritonavir/ombitasvir+dasabuvir (PrOD) plus ribavirin with warfarin, according to a case report published online Nov. 3 in the Journal of Clinical Pharmacy and Therapeutics.

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Age at Cancer Diagnosis Key in Determining Later Cardiac Risk

TUESDAY, Nov. 8, 2016 (HealthDay News) -- The age at which cancer survivors are diagnosed with their disease may help predict their risk of death from cardiac disease, according to research published online Nov. 7 in Circulation.

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Five Strategies Can Reduce Risk of Medical Lawsuits

MONDAY, Nov. 7, 2016 (HealthDay News) -- Five strategies can be employed by physicians in order to help reduce the risk of lawsuits, according to an article published in Medical Economics.

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PCSK9, LDL-C Link Only Seen for Patients With Highest HbA1c

MONDAY, Nov. 7, 2016 (HealthDay News) -- For patients with type 1 diabetes (T1D), the correlation between pro-protein convertase subtilisin/kexin type 9 (PCSK9) and low-density lipoprotein cholesterol (LDL-C) is only seen in the highest tertile for hemoglobin A1c (HbA1c), according to a study published online Nov. 2 in Diabetes, Obesity and Metabolism.

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Nonadherence in Nearly One-Third of Patients With HTN

MONDAY, Nov. 7, 2016 (HealthDay News) -- More than 30 percent of patients with hypertension are not adherent to antihypertensive drug therapy, according to a study published online Nov. 3 in the Journal of Evaluation in Clinical Practice.

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Women Have Worse Outcomes During 36 Months After ACS

FRIDAY, Nov. 4, 2016 (HealthDay News) -- In a study published in the Nov. 1 issue of The American Journal of Cardiology, among patients with acute coronary syndrome (ACS), women were found to have a higher mortality rate than men during 36 months of follow-up.

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Health Anxiety Takes Toll on Cardiovascular Health

FRIDAY, Nov. 4, 2016 (HealthDay News) -- People with high levels of health anxiety have about a 70 percent increased risk of ischemic heart disease (IHD), after taking into account other known risk factors, according to research published online Nov. 3 in BMJ Open.

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Deferred Revascularization Tied to Poor Outcomes in Diabetes

FRIDAY, Nov. 4, 2016 (HealthDay News) -- For patients with diabetes mellitus (DM), deferred revascularization is associated with poor medium-term outcomes, according to a study published in the Nov. 1 issue of The American Journal of Cardiology.

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Experience of Spouses Explored in Pre-Heart Transplant Period

FRIDAY, Nov. 4, 2016 (HealthDay News) -- In a review published online Nov. 2 in the Journal of Clinical Nursing, six themes are identified among spouses of heart transplant recipients, some of which are associated with high levels of stress.

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Half of Americans Have at Least One Chronic Health Condition

THURSDAY, Nov. 3, 2016 (HealthDay News) -- More than half of Americans have at least one chronic disease, mental illness, or problem with drugs or alcohol, according to a study published online recently in Psychology, Health & Medicine.

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Myocarditis ID'd With Ipilimumab + Nivolumab in Melanoma

THURSDAY, Nov. 3, 2016 (HealthDay News) -- Patients with melanoma treated with a combination of ipilimumab and nivolumab may be at risk for a potentially fatal T-cell-driven drug reaction, according to a report published in the Nov. 3 issue of the New England Journal of Medicine.

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Ambulatory IV Diuretics Cut Costs in Decompensated Heart Failure

THURSDAY, Nov. 3, 2016 (HealthDay News) -- Ambulatory, high-dose intravenous diuretic therapy seems to be cost saving for decompensated heart failure, according to a study published in the Nov. 1 issue of The American Journal of Cardiology.

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Increased Global, Subcutaneous Inflammation in Psoriasis

THURSDAY, Nov. 3, 2016 (HealthDay News) -- Psoriasis patients have increased global arterial inflammation and subcutaneous inflammation, according to a study published online Oct. 27 in the British Journal of Dermatology.

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Community Pharmacists Play Role in Providing Preventive Care

WEDNESDAY, Nov. 2, 2016 (HealthDay News) -- Community pharmacists are well suited to provide clinical preventive services, including education, screenings, and making referrals, according to a report published in the Oct. 27 issue of the U.S. Centers for Disease Control and Prevention's Preventing Chronic Disease.

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Incidence of Statin-Associated T2DM Relatively Low

WEDNESDAY, Nov. 2, 2016 (HealthDay News) -- For patients without diabetes, the incidence of statin-associated type 2 diabetes mellitus (T2DM) is relatively low, according to research published in the Nov. 1 issue of The American Journal of Cardiology.

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Impact of HbA1c, BMI Changes on Lipids Varies As Children Age

WEDNESDAY, Nov. 2, 2016 (HealthDay News) -- As children age, the impact of changes in hemoglobin A1c (HbA1c) and body mass index (BMI) on low-density lipoprotein (LDL) and non-high-density lipoprotein (non-HDL) cholesterol levels increases, according to a study published online Oct. 20 in Diabetes Care.

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Similar Complication Rate for Transvenous, Subcutaneous ICDs

TUESDAY, Nov. 1, 2016 (HealthDay News) -- For patients at risk for sudden cardiac death, the rate of complications is similar with transvenous implantable cardioverter-defibrillators (TV-ICDs) and subcutaneous ICDs (S-ICDs), although the nature of complications differs, according to a study published in the Nov. 8 issue of the Journal of the American College of Cardiology.

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Benefit of Exercise on Resting Pulse Rate in Seniors Unclear

TUESDAY, Nov. 1, 2016 (HealthDay News) -- A long-term moderate-intensity physical activity (PA) intervention may reduce resting pulse rate (RPR) among older adults, according to a study published online Oct. 27 in the Journal of the American Geriatrics Society.

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