November 2015 Briefing - Internal Medicine

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Here are what the editors at HealthDay consider to be the most important developments in Internal Medicine for November 2015. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

FDA Approves First Flu Vaccine Containing an Adjuvant

MONDAY, Nov. 30, 2015 (HealthDay News) -- The first seasonal influenza vaccine with an adjuvant has been approved for use in seniors, according to the U.S. Food and Drug Administration.

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Air Pollution Raises CVD Risks in Women With Diabetes

MONDAY, Nov. 30, 2015 (HealthDay News) -- Long periods of exposure to air pollution -- including dust and car exhaust -- heightens cardiovascular risks for women with diabetes, according to a study published online Nov. 25 in the Journal of the American Heart Association.

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Review: Changes in Vending Machines Can Promote Health

MONDAY, Nov. 30, 2015 (HealthDay News) -- Pricing and availability strategies can improve nutritional quality of purchases from vending machines, according to a review published in the December issue of Obesity Reviews.

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Basal Insulin Peglispro Beats Glargine for Glycemic Control

MONDAY, Nov. 30, 2015 (HealthDay News) -- For patients with type 2 diabetes, basal insulin peglispro (BIL) provides better glycemic control than insulin glargine, with increased triglycerides, aminotransferases, and liver fat content, according to a study published online Nov. 23 in Diabetes Care.

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Telephone Counseling Benefits Overweight Breast CA Survivors

MONDAY, Nov. 30, 2015 (HealthDay News) -- Telephone weight-loss counseling is similarly effective to in-person counseling for breast cancer survivors with a body mass index ≥25 kg/m², according to a study published online Nov. 23 in the Journal of Clinical Oncology.

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Neurotoxicity Seen With Acyclovir at Recommended Dose in Dialysis

MONDAY, Nov. 30, 2015 (HealthDay News) -- Acyclovir-induced neurotoxicity should be considered for patients with herpes zoster on hemodialysis, according to a case report published online Nov. 21 in the Journal of Dermatology.

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Trimethoprim-Induced Aseptic Meningitis Described

MONDAY, Nov. 30, 2015 (HealthDay News) -- Drug-induced aseptic meningitis following trimethoprim use has been described in a research letter published online Nov. 20 in the International Journal of Rheumatic Diseases.

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Nonalcoholic Fatty Liver Disease Predicts MACE in STEMI

MONDAY, Nov. 30, 2015 (HealthDay News) -- For patients without diabetes with ST-segment myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI), nonalcoholic fatty liver disease (FLD) independently predicts impaired myocardial perfusion and adverse in-hospital outcomes, according to a study published in the Dec. 15 issue of The American Journal of Cardiology.

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AAFP Recommends Doctors Explore Use of Social Media

WEDNESDAY, Nov. 25, 2015 (HealthDay News) -- The use of social media channels and associated benefits for physicians are highlighted in a recent article published by the American Academy of Family Physicians (AAFP). And guidelines are provided for physicians wishing to become active in social media.

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C. Difficile Infection Tied to Higher Risk of Post-Op Mortality

WEDNESDAY, Nov. 25, 2015 (HealthDay News) -- Patients at VA hospitals who contracted Clostridium difficile following surgery were five times more likely to die and 12 times more likely to suffer postoperative morbidity, according to findings published online Nov. 25 in JAMA Surgery.

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Dermatologic Drug Prices Up Substantially From 2009

WEDNESDAY, Nov. 25, 2015 (HealthDay News) -- Between 2009 and 2015, retail prices of brand-name dermatologic drugs rose 401 percent, on average, and generics were up 279 percent between 2011 and 2014, according to research published online Nov. 25 in JAMA Dermatology.

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Cost of Private Rooms Less Than That Associated With Infections

WEDNESDAY, Nov. 25, 2015 (HealthDay News) -- Patients in private hospital rooms are less likely to develop infections, which saves hospitals money in the long run, according to a study published online recently in the Journal of Critical Care.

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No Direct Survival Effect for Moderate Drinking in Seniors

WEDNESDAY, Nov. 25, 2015 (HealthDay News) -- For older adults, light-to-moderate drinking does not have a protective effect on mortality after adjustment for health status and physical activity, according to a study published online Nov. 23 in the Journal of the American Geriatrics Society.

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CDC: PrEP Rx Needs to Increase for Optimal HIV Prevention

WEDNESDAY, Nov. 25, 2015 (HealthDay News) -- Too few Americans who are at risk for HIV infection are taking Truvada (emtricitabine and tenofovir disoproxil fumarate) -- a daily pill that could protect them against the virus, and health care providers must help boost patient awareness and use of the drug, federal health officials report.

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Early-Stage Cervical CA Diagnoses in Young Women Up Since ACA

WEDNESDAY, Nov. 25, 2015 (HealthDay News) -- More early-stage cervical cancers have been diagnosed among young U.S. women since a key provision of the Affordable Care Act went into effect, according to a research letter published in the Nov. 24 issue of the Journal of the American Medical Association.

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CBT, Exercise Show Benefit in Chronic Fatigue Syndrome

TUESDAY, Nov. 24, 2015 (HealthDay News) -- Cognitive behavioral therapy, and graded exercise therapy are among the best available treatments for extended relief of chronic fatigue syndrome. The new findings were published online recently in The Lancet Psychiatry.

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Breastfeeding May Reduce Risk of T2DM for Women With GDM

TUESDAY, Nov. 24, 2015 (HealthDay News) -- Breastfeeding for two months or more may reduce the odds of developing type 2 diabetes for mothers who had already experienced gestational diabetes in the past; and the longer a woman breastfeeds, the lower the odds of type 2 diabetes, according to research published online Nov. 24 in the Annals of Internal Medicine.

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Music Can Help Doctors Develop Relationships With Patients

TUESDAY, Nov. 24 2015 (HealthDay News) -- For one physician, writing songs has improved her self-awareness and strengthened her relationships with patients, according to an article published by the American Medical Association.

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Central Sleep Apnea Predicts Atrial Fibrillation in Older Men

TUESDAY, Nov. 24, 2015 (HealthDay News) -- Central sleep apnea and Cheyne Stokes respiration predict incident atrial fibrillation in older men, according to a study published online Nov. 23 in the American Journal of Respiratory and Critical Care Medicine.

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Six Months of Walnut Consumption Ups Dietary Quality

TUESDAY, Nov. 24, 2015 (HealthDay News) -- The inclusion of walnuts in an ad libitum diet for six months is associated with improved diet quality, according to a study published online Nov. 23 in BMJ Open Diabetes Research & Care.

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ACP: Physicians Should Prescribe Generic Meds If Possible

TUESDAY, Nov. 24, 2015 (HealthDay News) -- Physicians should prescribe generic medications whenever possible, keeping in mind that generics have comparable effectiveness to brand name medications and are associated with reduced costs and increased adherence, according to new guidelines published online Nov. 24 in the Annals of Internal Medicine.

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Universal HCV Opt-Out Screening in Prisons Cost-Effective

TUESDAY, Nov. 24, 2015 (HealthDay News) -- Universal opt-out hepatitis C virus (HCV) screening in prisons is cost-effective and can reduce HCV transmission outside of prisons, according to research published online Nov. 24 in the Annals of Internal Medicine.

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Confusion Surrounding Osteoarthritis in Primary Care

TUESDAY, Nov. 24, 2015 (HealthDay News) -- There is confusion between patients and doctors about osteoarthritis (OA) and its context within multimorbidity, according to a study published in the November/December issue of the Annals of Family Medicine.

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CYP2C19 Polymorphism Impacts Response to PPI Tx in GERD

MONDAY, Nov. 23, 2015 (HealthDay News) -- CYP2C19 polymorphism impacts response to proton pump inhibitor (PPI) treatment in gastroesophageal reflux disease (GERD), with lower efficacy rates for rapid metabolizer (RM) genotypes, according to a study published online Nov. 18 in the Journal of Gastroenterology and Hepatology.

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Risk of Second Event High for Young Women After MI, Stroke

MONDAY, Nov. 23, 2015 (HealthDay News) -- Young women who survive a myocardial infarction (MI) or ischemic stroke continue to face an increased mortality risk -- or another MI or stroke, according to a study published online Nov. 23 in JAMA Internal Medicine.

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Higher Resting Heart Rate Tied to Higher Risk of Mortality

MONDAY, Nov. 23, 2015 (HealthDay News) -- A higher resting heart rate may indicate higher risk of premature mortality, researchers suggest. The report was published online Nov. 23 in CMAJ, the journal of the Canadian Medical Association.

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Bowel Function Index Valid for Opioid-Induced Constipation

MONDAY, Nov. 23, 2015 (HealthDay News) -- The Bowel Function Index (BFI) is a simple assessment tool for opioid-induced constipation, which is responsive to changes in symptom severity and has a threshold indicating constipation, according to consensus recommendations published online Nov. 19 in Pain Medicine.

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Citywide Colon Cancer Control Coalition Ups Screening in NYC

MONDAY, Nov. 23, 2015 (HealthDay News) -- A citywide colon cancer control coalition can increase colorectal cancer screening and address health disparities, according to a report published online Nov. 23 in Cancer.

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Fatal Train Derailment Likely Due to Undiagnosed Sleep Apnea

MONDAY, Nov. 23, 2015 (HealthDay News) -- Findings from a National Transportation Safety Board (NTSB) investigation into a train derailment highlight the importance of diagnosing obstructive sleep apnea, according to a report published in the November/December issue of the Annals of Family Medicine.

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Comorbid Stress, Depressive Symptoms Common in Diabetes

MONDAY, Nov. 23, 2015 (HealthDay News) -- For individuals with diabetes, comorbid stress and/or depressive symptoms are common and increase risks for adverse cardiovascular (CV) outcomes, according to a study published online Nov. 17 in Diabetes Care.

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Individual Glycemic Responses to Foods Found to Differ Greatly

MONDAY, Nov. 23, 2015 (HealthDay News) -- People have very different glycemic responses to the same food -- with some showing large blood glucose spikes even after eating supposedly healthy choices. Researchers said the findings, published in the Nov. 19 issue of Cell, underscore the message that there is no "one-size-fits-all" diet.

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FDA Grants Approval for Genetically Engineered Salmon

FRIDAY, Nov. 20, 2015 (HealthDay News) -- The U.S. Food and Drug Administration approved on Thursday a Massachusetts company's request to produce genetically modified salmon.

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Yoga May Help Maintain Quality of Life for Prostate Cancer Patients

FRIDAY, Nov. 20, 2015 (HealthDay News) -- Yoga may benefit men who are undergoing radiation therapy for prostate cancer, according to a small study. The research was presented at the Society of Integrative Oncology's international conference, held from Nov. 14 to 16 in Boston.

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Aetna Offers Targeted Health Plans for Diabetes Care

FRIDAY, Nov. 20, 2015 (HealthDay News) -- Aetna is offering targeted diabetes plans, which include low copays for specialists that patients with diabetes need, as well as free supplies and a care management program, according to a report published by Kaiser Health News.

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Bursts of High-Intensity Interval Training Beneficial for Older Men

FRIDAY, Nov. 20, 2015 (HealthDay News) -- A low-volume, high-intensity interval training (HIIT) program is effective for improving muscle power in older sedentary men, according to a letter to the editor published online Nov. 17 in the Journal of the American Geriatrics Society.

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Genetic Risk Score Can Differentiate Type 1, 2 Diabetes

FRIDAY, Nov. 20, 2015 (HealthDay News) -- A genetic risk score (GRS) can distinguish type 1 diabetes (T1D) from type 2 diabetes (T2D), according to a study published online Nov. 17 in Diabetes Care.

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Terlipressin Therapy Can Induce Hyponatremia

FRIDAY, Nov. 20, 2015 (HealthDay News) -- Terlipressin therapy can induce hyponatremia, according to a case report published online Nov. 17 in the Journal of Clinical Pharmacy and Therapeutics.

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Slow Uptake of Women's Libido-Boosting Pill

FRIDAY, Nov. 20, 2015 (HealthDay News) -- Uptake of the women's libido-boosting pill flibanserin (Addyi) has been slow since its approval, according to a report published by Bloomberg Business.

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FDA Approves Narcan Nasal Spray to Counter Opioid Overdose

THURSDAY, Nov. 19, 2015 (HealthDay News) -- Narcan (naloxone hydrochloride) nasal spray has been approved by the U.S. Food and Drug Administration to stop or reverse an overdose of opioids.

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Most IV HTN Meds Ordered for Patients With SBP <180 mm Hg

THURSDAY, Nov. 19, 2015 (HealthDay News) -- Intravenous (IV) antihypertensives are often ordered and administered for patients with asymptomatic uncontrolled blood pressure (BP) levels that are not associated with immediate cardiovascular risk, according to a study published online Nov. 12 in the Journal of Hospital Medicine.

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E-Portfolio Developed to Assess Millennial Med Students

THURSDAY, Nov. 19, 2015 (HealthDay News) -- Electronic portfolios are being used to transform medical students' assessments and track progress as students advance through medical training, according to a report published by the American Medical Association (AMA).

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Bright Light Therapy Might Also Treat Nonseasonal Depression

THURSDAY, Nov. 19, 2015 (HealthDay News) -- Light therapy, a treatment for seasonal affective disorder, may also benefit nonseasonal depression, according to research published online Nov. 18 in JAMA Psychiatry.

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Social Jetlag Tied to Prediabetes, Cardiovascular Disease Risk

THURSDAY, Nov. 19, 2015 (HealthDay News) -- Social jetlag due to a habitual discrepancy between endogenous circadian rhythm and actual sleep times, imposed by social obligations, is associated with metabolic risk factors that are linked to cardiovascular disease and prediabetes, according to a study published online Nov. 18 in the Journal of Clinical Endocrinology & Metabolism.

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Diabetes Predicts Worse Survival in Renal Cell Carcinoma

THURSDAY, Nov. 19, 2015 (HealthDay News) -- Diabetes mellitus is associated with worse prognosis in terms of progression-free, overall, and cancer-specific survival in patients with renal cell carcinoma treated surgically, according to a study published in the December issue of The Journal of Urology.

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Maintenance of LDL, HbA1c Goals With Pharmacist-Led Program

THURSDAY, Nov. 19, 2015 (HealthDay News) -- Veterans with type 2 diabetes had durable maintenance of their low-density lipoprotein (LDL) cholesterol and hemoglobin A1c (A1C) goals, but not systolic blood pressure (SBP) goals, after discharge from a pharmacist-managed ambulatory care clinic, in a study published in the November issue of Diabetes Spectrum.

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Nicotine, Toxicants Up With Smokeless Tobacco Exposure

WEDNESDAY, Nov. 18, 2015 (HealthDay News) -- Smokeless tobacco users have higher levels of nicotine and carcinogenic tobacco-specific nitrosamines compared with exclusive cigarette smokers, according to a study published online Nov. 18 in Cancer Epidemiology, Biomarkers & Prevention.

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Meta-Analysis: Rosuvastatin May Be Superior for Plaque Regression

WEDNESDAY, Nov. 18, 2015 (HealthDay News) -- Rosuvastatin appears to be more effective than atorvastatin for regression of coronary atherosclerotic plaques, according to a meta-analysis published in the Nov. 15 issue of The American Journal of Cardiology.

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Sildenafil Improves Insulin Sensitivity in Prediabetes

WEDNESDAY, Nov. 18, 2015 (HealthDay News) -- For patients with prediabetes, three-month sildenafil treatment improves insulin sensitivity, according to a study published online Nov. 18 in the Journal of Clinical Endocrinology & Metabolism.

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Pioglitazone Found to Help Some With Unremitting Depression

WEDNESDAY, Nov. 18, 2015 (HealthDay News) -- A new small study is adding evidence to the theory that insulin resistance may play a leading role in some cases of depression. Findings from the study were published online Oct. 12 in Psychiatry Research.

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Review: El Niño Southern Oscillation Has Effects on Skin

WEDNESDAY, Nov. 18, 2015 (HealthDay News) -- The El Niño Southern Oscillation (ENSO) climate phenomenon impacts skin and skin-related disease, according to a review published in the December issue of the International Journal of Dermatology.

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Burnout Reduces Readiness to Change Teaching Approaches

WEDNESDAY, Nov. 18, 2015 (HealthDay News) -- Occupational burnout appears to reduce clinical faculty members' readiness to change teaching approaches, according to a study published online Nov. 13 in the Journal of Evaluation in Clinical Practice.

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Group Medicine Appointments Effective for Glycemic Control

WEDNESDAY, Nov. 18, 2015 (HealthDay News) -- Medical management delivered via group medical appointments (GMAs) appears to be effective for glycemic control in patients with type 2 diabetes, according to research published in the November issue of Diabetes Spectrum.

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Hypertension-Linked ER Visits Common and Increasing

WEDNESDAY, Nov. 18, 2015 (HealthDay News) -- Hypertension-related emergency department visits are relatively common and increased from 2006 to 2012, according to a study published in the Dec. 1 issue of The American Journal of Cardiology.

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AAFP: Expected 0.5 Percent Pay Increase Reduced to Zero

WEDNESDAY, Nov. 18, 2015 (HealthDay News) -- A small but promised Medicare pay increase has effectively been reduced to zero for all physician specialties, according to the final 2016 Medicare physician fee schedule and a report published by the American Academy of Family Physicians.

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Vitamin D Supplementation Doesn't Cut Colds in Asthma

WEDNESDAY, Nov. 18, 2015 (HealthDay News) -- Vitamin D supplementation does not reduce cold severity or frequency among adults with mild-to-moderate asthma, according to a study published online Nov. 5 in the American Journal of Respiratory and Critical Care Medicine.

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Risk of Anaphylaxis Among IV Iron Products Compared

TUESDAY, Nov. 17, 2015 (HealthDay News) -- The risk of anaphylaxis associated with first exposure to intravenous (IV) iron is highest for iron dextran and lowest for iron sucrose, according to a study published in the Nov. 17 issue of the Journal of the American Medical Association.

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Testosterone Levels Not Linked to Autonomic Neuropathy in T1DM

TUESDAY, Nov. 17, 2015 (HealthDay News) -- For men with type 1 diabetes, testosterone levels are not associated with cardiovascular autonomic neuropathy (CAN), according to a study published online Nov. 12 in The Journal of Sexual Medicine.

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CDC: Rates of Chlamydia, Gonorrhea, Syphilis Up

TUESDAY, Nov. 17, 2015 (HealthDay News) -- In 2014, 1.4 million cases of chlamydia were reported to the U.S. Centers for Disease Control and Prevention -- a 2.8 percent increase since 2013. This is the highest number of cases of any sexually transmitted disease (STD) ever reported to the CDC, the government researchers said in their annual report.

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Prostate Cancer Screening, Detection Both Down in U.S.

TUESDAY, Nov. 17, 2015 (HealthDay News) -- Fewer U.S. men are being screened for prostate cancer, and fewer cases of the disease are being diagnosed nationwide. These findings, published in the Nov. 17 issue of the Journal of the American Medical Association, suggest that the U.S. Preventive Services Task Force (USPSTF) recommendations have had an impact.

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Prognostic Biomarkers ID'd in Pulmonary Hypertension

TUESDAY, Nov. 17, 2015 (HealthDay News) -- Biomarkers have been identified for the risk of lung transplantation and death in patients with pulmonary arterial hypertension (PAH), according to a study published online Oct. 26 in the Annals of the American Thoracic Society.

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GLP-1 Receptor Agonists Can Manage Postprandial Glucose

TUESDAY, Nov. 17, 2015 (HealthDay News) -- Glucagon-like peptide 1 (GLP-1) receptor agonists appear beneficial for postprandial glucose management in type 2 diabetes, according to a report published in the October issue of Clinical Diabetes.

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Therapeutic Hypothermia May Help Cardiac Arrest Patients

TUESDAY, Nov. 17, 2015 (HealthDay News) -- Patients who receive therapeutic hypothermia may be nearly three times more likely to survive cardiac arrest, according to a study published online Nov. 16 in Circulation.

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Reduced Mortality Risk Seen for Coffee Drinkers

TUESDAY, Nov. 17, 2015 (HealthDay News) -- People who drink coffee may live longer than those who don't -- with lower risks of early mortality from cardiovascular disease and neurological conditions such as Parkinson's disease, according to research published online Nov. 16 in Circulation.

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Preventive HIV Treatment Shown Effective at Health Clinics

TUESDAY, Nov. 17, 2015 (HealthDay News) -- Real-world application of pre-exposure prophylaxis (PrEP) medications appears to be effective for the prevention of HIV, but racial discrepancies exist, new research suggests. The studies appear online Nov. 16 in JAMA Internal Medicine.

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Continuation of Antibiotics for UTI Often Inappropriate

TUESDAY, Nov. 17, 2015 (HealthDay News) -- For patients with urinary tract infections (UTIs), initiation of antibiotics in the emergency department is frequently inappropriate, as is continuation of antibiotics after admission, according to a study published online Nov. 12 in the Journal of Hospital Medicine.

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Knee Bracing No Benefit Over Nonoperative Program in Knee OA

TUESDAY, Nov. 17, 2015 (HealthDay News) -- For patients with knee osteoarthritis (OA), knee bracing offers no benefit over a multidisciplinary nonoperative program, according to a study published online Nov. 12 in the International Journal of Rheumatic Diseases.

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Head Lice infestation Could Cause Iron Deficiency Anemia

TUESDAY, Nov. 17, 2015 (HealthDay News) -- Head lice infestation could cause iron deficiency anemia in the absence of any other cause, according to a case report published online Nov. 5 in BMJ Case Reports.

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Benefits for Mindfulness-Based Interventions in Primary Care

MONDAY, Nov. 16, 2015 (HealthDay News) -- Mindfulness-based interventions (MBIs) are moderately efficacious for improving general health in primary care, and are effective for improving mental health and quality of life, according to a meta-analysis published in the November/December issue of the Annals of Family Medicine.

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HbA1c Control on Metformin Predicts Durable Control in T2DM

MONDAY, Nov. 16, 2015 (HealthDay News) -- For adolescents with type 2 diabetes, hemoglobin A1c (HbA1c) after metformin monotherapy predicts the likelihood of durable glycemic control on oral therapy, according to a study published online Nov. 4 in Diabetes Care.

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Primary Aldosteronism Screen Cost-Effective in Resistant HTN

MONDAY, Nov. 16, 2015 (HealthDay News) -- For patients with resistant hypertension (RH), computed tomography (CT) scanning followed by adrenal venous sampling (AVS) is a cost-effective screen for primary aldosteronism (PA), according to a study published online Nov. 10 in Circulation: Cardiovascular Quality and Outcomes.

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Transitional Care Interventions Cut Risk of Readmission in CHF

MONDAY, Nov. 16, 2015 (HealthDay News) -- For patients with congestive heart failure, transitional care interventions (TCIs), especially high-intensity TCIs, are effective for reducing the risks of readmission and emergency department visits, according to a review published in the November/December issue of the Annals of Family Medicine.

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FDA: Automated Endoscope Reprocessors Recalled

MONDAY, Nov. 16, 2015 (HealthDay News) -- Nearly 2,800 machines used to disinfect medical scopes are being recalled because they may put patients at risk for infections, the U.S. Food and Drug Administration says.

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White-Coat, Masked HTN Tied to Target Organ Complications

MONDAY, Nov. 16, 2015 (HealthDay News) -- Both white-coat hypertension (WCH) and masked hypertension (MH) are associated with target organ complications and cardiovascular event risk, according to a study published in the Nov. 17 issue of the Journal of the American College of Cardiology.

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Low FODMAP Diet Cuts Irritable Bowel Syndrome Symptoms

FRIDAY, Nov. 13, 2015 (HealthDay News) -- A diet with reduced content of fermentable short-chain carbohydrates (fermentable oligo-, di-, monosaccharides, and polyols [FODMAPs]) reduces symptoms of irritable bowel syndrome (IBS), with reductions similar to those seen for traditional dietary advice, according to a study published in the November issue of Gastroenterology.

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Impaired Kidney Function May Raise Cancer Risk

FRIDAY, Nov. 13, 2015 (HealthDay News) -- Kidney failure and having a kidney transplant may increase the risk for certain types of cancer, according to a study published online Nov. 12 in the Journal of the American Society of Nephrology.

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Radial Artery Access Reduces Mortality, Major Bleeds in ACS

FRIDAY, Nov. 13, 2015 (HealthDay News) -- For patients with acute coronary syndrome managed with invasive procedures, radial artery access reduces mortality, major coronary adverse events, and major bleeding compared to femoral artery access, according to a meta-analysis published online Nov. 10 in the Annals of Internal Medicine.

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CDC: Adult Smoking Rate Falls to New Low in the United States

FRIDAY, Nov. 13, 2015 (HealthDay News) -- Under 17 percent of adults said they smoked in 2014, down from nearly 21 percent in 2005. And the average number of cigarettes smoked daily fell from nearly 17 to fewer than 14 by 2014. The latest numbers are published in the Nov. 13 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Facilitating Shared Decision-Making Can Cut Antibiotic Use

FRIDAY, Nov. 13, 2015 (HealthDay News) -- For patients with acute respiratory infections (ARIs), interventions that aim to facilitate shared decision-making reduce antibiotic use in primary care, according to a review published online Nov. 12 in The Cochrane Library.

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Levodopa Shows Promise Against Macular Degeneration

FRIDAY, Nov. 13, 2015 (HealthDay News) -- Levodopa (L-dopa) might hold potential for preventing or treating macular degeneration, according to a study published online Oct. 30 in The American Journal of Medicine.

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Hormonal Status Impacts Genetic Variation, CIMT Link

FRIDAY, Nov. 13, 2015 (HealthDay News) -- Hormonal status seems to interact with genetic variants to influence cardiovascular phenotypes, especially those within the innate immunity pathway related to carotid artery intima-medial thickness (CIMT), according to a study published online Oct. 27 in Physiological Genomics.

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Urinary Potassium Excretion Tied to Renal, Cardio Risk in T2DM

FRIDAY, Nov. 13, 2015 (HealthDay News) -- For patients with type 2 diabetes, higher urinary potassium excretion is associated with decreased risk of renal and cardiovascular events, according to a study published online Nov. 12 in the Clinical Journal of the American Society of Nephrology.

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Intervention Cuts Potentially Inappropriate Meds in Seniors

FRIDAY, Nov. 13, 2015 (HealthDay News) -- An intervention (Optimizing Prescribing for Older People in Primary Care [OPTI-SCRIPT]) can reduce potentially inappropriate prescribing (PIP) in older patients, according to a study published in the November/December issue of the Annals of Family Medicine.

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Genetic Risk Score IDs Insulin Resistance, Change in IR

FRIDAY, Nov. 13, 2015 (HealthDay News) -- A genetic risk score based on 17 established insulin resistance (IR) variants and their effect sizes (weighted IR-GRS) is associated with IR at baseline and change in IR, but does not impact the effect of lifestyle intervention and metformin on IR, according to a study published online Nov. 2 in Diabetes.

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CDC: Half of Americans With HTN Don't Have BP Under Control

THURSDAY, Nov. 12, 2015 (HealthDay News) -- About 47 percent of individuals with hypertension do not have the condition under control, through either lifestyle changes or medications, according to a November data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics.

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PCI May Not Improve Survival for Some Heart Disease Patients

THURSDAY, Nov. 12, 2015 (HealthDay News) -- Patients with stable ischemic heart disease who undergo percutaneous coronary intervention (PCI) fare no better than those treated with medication and lifestyle changes alone, according to a report published in the Nov. 12 issue of the New England Journal of Medicine.

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CDC: Adult Obesity Still Rising in U.S., Youth Rates Hold Steady

THURSDAY, Nov. 12, 2015 (HealthDay News) -- Although obesity rates continued to climb among U.S. adults over the past decade, they stabilized for children and teens, according to a November data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics.

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Swiss Report Highlights Danger of Drug-Resistant Tuberculosis

THURSDAY, Nov. 12, 2015 (HealthDay News) -- Although antibiotics have largely eradicated tuberculosis (TB) in the United States in recent decades, researchers say evidence is mounting that the bacteria is becoming increasingly resistant to these medications. Details of a recent Swiss case are reported in the Nov. 12 issue of the New England Journal of Medicine.

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Risk Prediction Equations Created for Diabetes Complications

THURSDAY, Nov. 12, 2015 (HealthDay News) -- New risk prediction equations have been developed and validated to estimate the risk of blindness and lower limb amputation in patients with diabetes, according to a study published online Nov. 11 in The BMJ.

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Incretin Use May Up Pancreatic CA Risk, but Only in Short Term

THURSDAY, Nov. 12, 2015 (HealthDay News) -- The risk of pancreatic cancer is increased in recent starters of incretins, but the elevated risk drops to baseline levels with prolonged use, according to a study published online Nov. 5 in Diabetes, Obesity and Metabolism.

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About Half of Pulmonologists Tend to Offer LDCT Screening

THURSDAY, Nov. 12, 2015 (HealthDay News) -- About half of pulmonologists have a propensity for guideline-concordant low-dose computed tomography (LDCT) screening for lung cancer, according to a study published in the November issue of the Annals of the American Thoracic Society.

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Exercise Stress ECG Underutilized As Initial Test for Suspected CAD

THURSDAY, Nov. 12, 2015 (HealthDay News) -- Exercise stress electrocardiography (ExECG) can yield substantial data from risk stratification in suspected or known coronary artery disease, according to a state-of-the-art paper published in the Nov. 1 issue of JACC: Cardiovascular Imaging.

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Noon Best Time to Get Vitamin D From Sun for Minimal Cancer Risk

THURSDAY, Nov. 12, 2015 (HealthDay News) -- Variations in ultraviolet (UV) A and B radiation with increasing latitude and during the day impact skin cancer risk, according to a study published online Nov. 6 in the International Journal of Dermatology.

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Substantial Increase in Costs for Uncontrolled Asthma

THURSDAY, Nov. 12, 2015 (HealthDay News) -- A considerable proportion of patients with mild to moderate asthma are symptomatically uncontrolled, and uncontrolled asthma is associated with significantly increased costs, according to a study published online Nov. 3 in Allergy.

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Leg Strength Linked to Healthier Brain Aging

WEDNESDAY, Nov. 11, 2015 (HealthDay News) -- Leg strength is strongly linked with healthier brain aging, according to research published online Nov. 10 in Gerontology.

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ACP Issues Guidance on 'Concierge' Practices

TUESDAY, Nov. 10, 2015 (HealthDay News) -- Direct patient contracting practices (DPCPs), in which patients pay out of pocket for some or all services provided by the practice, are growing in popularity, according to a position paper published online Nov. 10 in the Annals of Internal Medicine.

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Few Adults With Severe Mental Illness Screened for Diabetes

WEDNESDAY, Nov. 11, 2015 (HealthDay News) -- About 30 percent of adults with severe mental illness (SMI) taking antipsychotic medications undergo diabetes-specific screening using validated screening measures, according to a study published online Nov. 9 in JAMA Internal Medicine.

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Central Obesity Is Hazardous, Even at a Normal Weight

WEDNESDAY, Nov. 11, 2015 (HealthDay News) -- Individuals with central obesity but of normal weight according to body mass index (BMI) have a higher risk of premature mortality than overweight or obese people, according to research published online Nov. 10 in the Annals of Internal Medicine.

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Self-Managing Anticoagulation May Benefit Heart Valve Patients

TUESDAY, Nov. 10, 2015 (HealthDay News) -- Patients with mechanical heart valves may benefit from managing their own oral anticoagulant therapy, according to a study published online Nov. 9 in the Annals of Thoracic Surgery.

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Insufficient Evidence on Silicone Breast Implant Safety

TUESDAY, Nov. 10, 2015 (HealthDay News) -- After years of study, a new analysis finds there is still insufficient evidence on whether silicone breast implants are linked to any long-term health effects. The report, published online Nov. 10 in the Annals of Internal Medicine, is the latest round in the long debate over silicone breast implant safety.

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Macrolides May Raise Cardiovascular Risks

TUESDAY, Nov. 10, 2015 (HealthDay News) -- Macrolides are associated with a small but measurable increased risk of sudden cardiac death, according to research published in the Nov. 17 issue of the Journal of the American College of Cardiology.

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Case Report Highlights Dangers of Natural Remedies

TUESDAY, Nov. 10, 2015 (HealthDay News) -- A case of accidental overdose of an Atropa belladonna preparation highlights the dangers of the use of herbal remedies, according to a case report published online Nov. 5 in BMJ Case Reports.

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Normal Coronary Angiogram at 65 Predicts Survival

TUESDAY, Nov. 10, 2015 (HealthDay News) -- Patients with normal or near-normal coronary angiogram (CA) results at age 65 years or older have significantly longer survival than the general population, according to a study published in the Nov. 15 issue of The American Journal of Cardiology.

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Three Renal Biomarkers Predict Outcome in Diabetes

TUESDAY, Nov. 10, 2015 (HealthDay News) -- Three renal biomarkers, acute kidney injury (AKI), albuminuria, and low estimated glomerular filtration rate (eGFR), considered separately or together, can predict adverse outcomes in diabetes, according to a study published online Oct. 28 in Diabetes Care.

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Expanding Rooming, Discharge Office Protocols Can Save Time

MONDAY, Nov. 9, 2015 (HealthDay News) -- Expanding protocols for rooming and discharge can allow physicians to free up an hour or more of time per day, according to the American Medical Association (AMA).

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Study Explores Comfort With Non In-Person Test Results

MONDAY, Nov. 9, 2015 (HealthDay News) -- Patients have different preferences for non in-person receipt of test results, with preferences varying by test, according to a study published in the November-December issue of the Journal of the American Board of Family Medicine.

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Exercise Capacity, Heart Rate Response Predict CAD Outcomes

MONDAY, Nov. 9, 2015 (HealthDay News) -- Exercise capacity (EC) and heart rate responses to exercise are effective predictors of short-term outcome among patients with stable coronary artery disease (CAD), according to a study published in the Nov. 15 issue of The American Journal of Cardiology.

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Web-Based CBT Program Cuts Suicidal Ideation in Interns

MONDAY, Nov. 9, 2015 (HealthDay News) -- A web-based cognitive behavioral therapy (wCBT) program is effective for preventing suicidal ideation among medical interns, according to a study published online Nov. 4 in JAMA Psychiatry.

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Doctors Can Often Miss Achilles Tendon Diagnosis

MONDAY, Nov. 9, 2015 (HealthDay News) -- About one-quarter of Achilles tendon ruptures are missed during doctors' initial examinations, according to a clinical review published in the November issue of the Journal of the American Osteopathic Association.

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Omega-3 Supplements Don't Help With Depression

FRIDAY, Nov. 6, 2015 (HealthDay News) -- There's little evidence that taking omega-3 fatty acid supplements helps treat depression, according to a review published online Nov. 5 in The Cochrane Library.

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Specific Insulin-Based Exercise Strategies Help in T1DM Pump Tx

FRIDAY, Nov. 6, 2015 (HealthDay News) -- Insulin-based strategies of basal rate reduction or pump cessation may be the best approach in avoiding hypoglycemia associated with exercise after lunch, according to a study published online Oct. 8 in Diabetes, Obesity & Metabolism.

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Emotional Intelligence Linked to Self-Management in COPD

FRIDAY, Nov. 6, 2015 (HealthDay News) -- Emotional intelligence, the capacity to understand and manage personal thoughts and feelings, is associated with self-management abilities and quality of life in chronic obstructive pulmonary disease (COPD), according to a study published online Oct. 26 in the Annals of the American Thoracic Society.

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Lipophilic Tops Hydrophilic Statins for Heart Failure

FRIDAY, Nov. 6, 2015 (HealthDay News) -- For patients with heart failure, lipophilic statin is superior to hydrophilic statin for cardiac function and inflammation, according to a meta-analysis published in the December issue of Cardiovascular Therapeutics.

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Updated Checklist for Reporting Diagnostic Accuracy Studies

FRIDAY, Nov. 6, 2015 (HealthDay News) -- An updated list of 30 essential items should be included in every report of a diagnostic accuracy study, according to the Standards for Reporting Diagnostic Accuracy Studies (STARD) 2015. These new guidelines have been published in several journals, including Radiology, Clinical Chemistry, and The BMJ.

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FDA Approves Genvoya to Treat HIV-1 Infection

THURSDAY, Nov. 5, 2015 (HealthDay News) -- A new treatment for HIV has been approved by the U.S. Food and Drug Administration. Genvoya -- a tablet containing elvitegravir, cobicistat, emtricitabine, and tenofovir alafenamide -- can be used to treat HIV-1 infection in adults and children 12 and older weighing at least 77 pounds.

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Doctors Who Order More Tests Have Fewer Malpractice Claims

THURSDAY, Nov. 5, 2015 (HealthDay News) --The more tests and treatments U.S. doctors order for patients, the less likely they are to be sued for malpractice, according to a study published online Nov. 4 in The BMJ.

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Branded Rx May Up the Power of Placebo

THURSDAY, Nov. 5, 2015 (HealthDay News) -- A brand-name label made a placebo tablet work as well as an active nonsteroidal anti-inflammatory drug, according to research published online Oct. 12 in Health Psychology.

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Poll: Americans Want Health Care Costs Kept in Check

THURSDAY, Nov. 5, 2015 (HealthDay News) -- Most Americans now support aggressive regulation to keep health care costs in check -- including price caps on drugs, medical devices, and payments to doctors and hospitals, a new HealthDay/Harris Poll has found.

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Sofosbuvir Tied to Rare Cases of Bradyarrhythmia

THURSDAY, Nov. 5, 2015 (HealthDay News) -- One of the new, highly effective drugs for treating hepatitis C can cause bradyarrhythmia in some patients, according to a research letter published in the Nov. 5 issue of the New England Journal of Medicine.

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CDC: Tapeworm Implicated in Case of Malignant Transformation

THURSDAY, Nov. 5, 2015 (HealthDay News) -- Cancer cells transmitted from a common tapeworm appear to have caused cancer-like tumors in a Colombian man with HIV -- the first known case of malignant transformation, U.S. health officials report in the Nov. 5 issue of the New England Journal of Medicine.

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Raloxifene Does Not Appear to Boost Cognition in Alzheimer's

THURSDAY, Nov. 5, 2015 (HealthDay News) -- Raloxifene doesn't benefit cognition in women who have mild to moderate dementia due to Alzheimer's disease, according to a small study published online Nov. 4 in Neurology.

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ACP Joins Amicus Curiae Brief to Supreme Court

THURSDAY, Nov. 5, 2015 (HealthDay News) -- The American College of Physicians (ACP) has joined other organizations in an amicus curiae brief to the Supreme Court, urging the court to uphold considerations of race and ethnicity in the medical school admissions process.

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Significant Variation in Tx Costs for Low-Risk Prostate Cancer

THURSDAY, Nov. 5, 2015 (HealthDay News) -- There is significant cost variation between competing treatments for low-risk prostate cancer, according to a study published online Nov. 2 in Cancer.

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Sleep-Disordered Breathing in REM Linked to Insulin Resistance

THURSDAY, Nov. 5, 2015 (HealthDay News) -- The correlation between sleep-disordered breathing (SDB) and glucose metabolism varies for rapid eye movement (REM) sleep and non-REM sleep, according to a study published in the Nov. 1 issue of the American Journal of Respiratory and Critical Care Medicine.

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Metformin Eligibility Up With eGFR Versus Serum Creatinine

THURSDAY, Nov. 5, 2015 (HealthDay News) -- Use of estimated glomerular filtration rate (eGFR) rather than serum creatinine (sCr) can expand metformin eligibility, according to a study published in the November issue of Diabetes Care.

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Adherence, Not Diet Type, Predicts Long-Term Weight Loss

WEDNESDAY, Nov. 4, 2015 (HealthDay News) -- Low-fat diets are no more effective than other types of diets for long-term weight loss, according to a review published online Oct. 29 in The Lancet Diabetes & Endocrinology.

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Sleep Patterns May Affect a Woman's Diabetes Risk

WEDNESDAY, Nov. 4, 2015 (HealthDay News) -- Women who experience a big increase in hours of sleep each night may face an increased risk of type 2 diabetes, new research suggests. The study appeared online Nov. 2 in Diabetologia.

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AMA: 6 Steps to Help Ensure Patients Get Preventive Care

WEDNESDAY, Nov. 4, 2015 (HealthDay News) -- Panel management, or population health management, can help physicians provide necessary preventive and chronic care to all patients regardless of their visit frequency, according to a report published by the American Medical Association (AMA).

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Doctors Should Consider Financial Factors Before Career Change

WEDNESDAY, Nov. 4, 2015 (HealthDay News) -- Financial and other factors should be considered before physicians change career direction, according to a report published in Medical Economics.

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CDC: Gonorrhea Showing More Resistance to Cefixime

WEDNESDAY, Nov. 4, 2015 (HealthDay News) -- The U.S. Centers for Disease Control and Prevention's latest tracking suggests that although gonorrhea resistance to the antibiotic treatment cefixime declined between 2011 and 2013, it started to rise again in 2014. The study findings are published as a research letter in the Nov. 3 issue of the Journal of the American Medical Association.

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Endovascular Tx Beats tPA Alone for Stroke Patients

WEDNESDAY, Nov. 4, 2015 (HealthDay News) -- Endovascular therapy with mechanical thrombectomy in ischemic stroke is superior to standard treatment with tissue plasminogen activator (tPA) for preserving brain function, according to research published in the Nov. 3 issue of the Journal of the American Medical Association.

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Guideline-Concordant Diabetes Care Similar With NPs, PCPs

WEDNESDAY, Nov. 4, 2015 (HealthDay News) -- The rates of processes of diabetes mellitus guideline-concordant care are similar, or slightly lower, for nurse practitioners (NPs) versus primary care physicians (PCPs), according to a study published in the October issue of the Journal of the American Geriatrics Society.

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HIV Does Not Worsen Outcomes of Liver Transplant in HCC

WEDNESDAY, Nov. 4, 2015 (HealthDay News) -- HIV infection has no impact on prognosis of liver transplantation (LT) for hepatocellular carcinoma (HCC), according to a study published online Oct. 30 in Hepatology.

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Prescription Medication Use on the Rise in the United States

WEDNESDAY, Nov. 4, 2015 (HealthDay News) -- More Americans than ever are taking prescription drugs, as well as using more of them, according to research published in the Nov. 3 issue of the Journal of the American Medical Association.

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Sweetened Drinks Linked to Higher Risk of Heart Failure

TUESDAY, Nov. 3, 2015 (HealthDay News) -- Regular consumption of soda or sweetened fruit drinks may increase risk for heart failure in men, according to research published online Nov. 2 in Heart.

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Online Cognitive Therapy May Benefit Some Patients

TUESDAY, Nov. 3, 2015 (HealthDay News) -- Online cognitive behavioral therapy can help with anxiety, depression, and emotional distress related to illness as much, if not more, than standard face-to-face interventions, according to research published online Nov. 2 in CMAJ, the journal of the Canadian Medical Association.

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GDM Risk Higher With More Abdominal Fat in First Trimester

TUESDAY, Nov. 3, 2015 (HealthDay News) -- Women with high levels of abdominal fat in their first trimester are at increased risk for diabetes later in pregnancy, according to research published online Nov. 2 in Diabetes Care.

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New Electronic Health Record Regulations Released

TUESDAY, Nov. 3, 2015 (HealthDay News) -- New electronic health record (EHR) regulations modify Stage 2 of the meaningful use program and finalize requirements for Stage 3, according to a report published by the American Medical Association (AMA).

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Benefits, Harms of HTN Drugs Should be Considered for Elderly

TUESDAY, Nov. 3, 2015 (HealthDay News) -- For elderly patients with hypertension, the benefits and risks associated with use of antihypertensive medications should be carefully considered, according to a review published online Oct. 26 in the Journal of Internal Medicine.

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H. pylori Triple Therapy Linked to Erythema Multiforme

TUESDAY, Nov. 3, 2015 (HealthDay News) -- Triple therapy for Helicobacter pylori can cause erythema multiforme, according to a case study published online Oct. 28 in The Journal of Dermatology.

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New Advisory OKs Some Athletes With Heart Conditions to Play

TUESDAY, Nov. 3, 2015 (HealthDay News) -- Some athletes with irregular heartbeat caused by long QT syndrome and athletes with long QT syndrome who have implanted pacemakers or defibrillators may be able to play competitive sports, according to new guidelines published online Nov. 2 in Circulation and the Journal of the American College of Cardiology.

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Chronic PPI Exposure Tied to Hyperparathyroidism in Elderly

TUESDAY, Nov. 3, 2015 (HealthDay News) -- Chronic proton pump inhibitor (PPI) exposure is associated with mild hyperparathyroidism in elderly adults, according to a study published in the October issue of the Journal of the American Geriatrics Society.

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Severe Obesity in Adults Costs Medicaid $8 Billion Annually

TUESDAY, Nov. 3, 2015 (HealthDay News) -- Severe obesity is putting a huge financial strain on both the U.S. Medicaid system and severely obese patients themselves, according to a report published in the November issue of Health Affairs.

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HPV Tied to Pyogenic Granuloma in Patients Without Warts

TUESDAY, Nov. 3, 2015 (HealthDay News) -- In patients without clinical evidence of warts, human papillomavirus type 2 (HPV-2) is associated with pyogenic granuloma, according to a study published online Oct. 22 in the International Journal of Dermatology.

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Prescribing Drugs 'Off-Label' Can Pose Serious Safety Risks

MONDAY, Nov. 2, 2015 (HealthDay News) -- Off-label drug use puts patients at risk for serious side effects, especially when scientific evidence is lacking, according to a study published online Nov. 2 in JAMA Internal Medicine.

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Competition for Fellowships Broke Records in 2015

MONDAY, Nov. 2, 2015 (HealthDay News) -- According to the American Medical Association (AMA), 2015 was a record-breaking year for fellowship applications.

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High-Intensity Interval Training Improves Metabolic Health

MONDAY, Nov. 2, 2015 (HealthDay News) -- High-intensity interval training (HIIT) seems to be beneficial for improving metabolic health, according to a meta-analysis published in the November issue of Obesity Reviews.

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More Sedentary Time for Females With Fibromyalgia

MONDAY, Nov. 2, 2015 (HealthDay News) -- Compared with controls, females with fibromyalgia spend more time in sedentary behaviors and less time engaged in physical activity, according to a study published in the November issue of Arthritis & Rheumatology.

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Medicare to Cover Advance Care Planning for Older Americans

MONDAY, Nov. 2, 2015 (HealthDay News) -- On Friday, Medicare announced that it will begin reimbursing doctors who work with patients to plan end-of-life care.

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Nasal Congestion No Better With Phenylephrine in Allergic Rhinitis

MONDAY, Nov. 2, 2015 (HealthDay News) -- For patients with seasonal allergic rhinitis (SAR), phenylephrine hydrochloride (PE HCl) is no better than placebo for relieving nasal congestion, according to a study published in the September-October issue of the Journal of Allergy and Clinical Immunology: In Practice.

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Displaying Prices to Providers Seems to Reduce Order Costs

MONDAY, Nov. 2, 2015 (HealthDay News) -- Displaying order prices to physicians seems to reduce order costs, according to a review published online Oct. 23 in the Journal of Hospital Medicine.

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Case Study: Bisphosphonate-Linked Osteonecrosis in Diabetes

MONDAY, Nov. 2, 2015 (HealthDay News) -- A case of bisphosphonate-related osteonecrosis of the jaw is described in an elderly patient with diabetes mellitus. The report is published in the October issue of the Journal of the American Geriatrics Society.

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Vitiligo Can Mask Symptoms of Acanthosis Nigricans

MONDAY, Nov. 2, 2015 (HealthDay News) -- Vitiligo can mask symptoms of acanthosis nigricans (AN), according to a case report published in the November issue of the International Journal of Dermatology.

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Ranolazine Bests Old School Antianginal Medications

MONDAY, Nov. 2, 2015 (HealthDay News) -- Newer antianginal (AA) medications such as ranolazine show substantial outcome improvements in chronic stable angina pectoris (CSA) compared to traditional medications, according to a study published in the Nov. 1 issue of The American Journal of Cardiology.

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Prediabetes Linked to Incident Cardiovascular Disease

MONDAY, Nov. 2, 2015 (HealthDay News) -- Prediabetes is associated with incident cardiovascular disease (CVD), although correlations vary with ethnicity and prediabetes definition, according to a study published online Oct. 20 in Diabetes Care.

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Fish Oil Supplementation Doesn't Cut Inflammatory Markers

MONDAY, Nov. 2, 2015 (HealthDay News) -- For healthy adults, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) supplementation does not reduce common markers of systemic inflammation, according to a study published online Oct. 26 in the Journal of Internal Medicine.

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