November 2015 Briefing - Diabetes & Endocrinology

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for November 2015. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Air Pollution Raises CVD Risks in Women With Diabetes

MONDAY, Nov. 30, 2015 (HealthDay News) -- Long periods of exposure to air pollution -- including dust and car exhaust -- heightens cardiovascular risks for women with diabetes, according to a study published online Nov. 25 in the Journal of the American Heart Association.

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Review: Changes in Vending Machines Can Promote Health

MONDAY, Nov. 30, 2015 (HealthDay News) -- Pricing and availability strategies can improve nutritional quality of purchases from vending machines, according to a review published in the December issue of Obesity Reviews.

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Basal Insulin Peglispro Beats Glargine for Glycemic Control

MONDAY, Nov. 30, 2015 (HealthDay News) -- For patients with type 2 diabetes, basal insulin peglispro (BIL) provides better glycemic control than insulin glargine, with increased triglycerides, aminotransferases, and liver fat content, according to a study published online Nov. 23 in Diabetes Care.

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AAFP Recommends Doctors Explore Use of Social Media

WEDNESDAY, Nov. 25, 2015 (HealthDay News) -- The use of social media channels and associated benefits for physicians are highlighted in a recent article published by the American Academy of Family Physicians (AAFP). And guidelines are provided for physicians wishing to become active in social media.

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Animal-Source, Low-Carb Diet Ups T2DM Risk With Past GDM

WEDNESDAY, Nov. 25, 2015 (HealthDay News) -- For women with a history of gestational diabetes mellitus (GDM), a low-carbohydrate diet (LCD), particularly one from animal-source foods, is associated with increased risk of type 2 diabetes mellitus (T2DM), according to a study published online Nov. 17 in Diabetes Care.

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Breastfeeding May Reduce Risk of T2DM for Women With GDM

TUESDAY, Nov. 24, 2015 (HealthDay News) -- Breastfeeding for two months or more may reduce the odds of developing type 2 diabetes for mothers who had already experienced gestational diabetes in the past; and the longer a woman breastfeeds, the lower the odds of type 2 diabetes, according to research published online Nov. 24 in the Annals of Internal Medicine.

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Music Can Help Doctors Develop Relationships With Patients

TUESDAY, Nov. 24 2015 (HealthDay News) -- For one physician, writing songs has improved her self-awareness and strengthened her relationships with patients, according to an article published by the American Medical Association.

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Six Months of Walnut Consumption Ups Dietary Quality

TUESDAY, Nov. 24, 2015 (HealthDay News) -- The inclusion of walnuts in an ad libitum diet for six months is associated with improved diet quality, according to a study published online Nov. 23 in BMJ Open Diabetes Research & Care.

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Exposure to Maternal Diabetes Impacts Youth Glycemic Control

TUESDAY, Nov. 24, 2015 (HealthDay News) -- Young people exposed to maternal diabetes during pregnancy have poorer glycemic control and β-cell function, particularly non-Hispanic blacks and Hispanics, according to a study published online Nov. 17 in Diabetes Care.

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ACP: Physicians Should Prescribe Generic Meds If Possible

TUESDAY, Nov. 24, 2015 (HealthDay News) -- Physicians should prescribe generic medications whenever possible, keeping in mind that generics have comparable effectiveness to brand name medications and are associated with reduced costs and increased adherence, according to new guidelines published online Nov. 24 in the Annals of Internal Medicine.

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Review Addresses Diagnosis of PCOS in Adolescents

MONDAY, Nov. 23, 2015 (HealthDay News) -- Unexplained persistent hyperandrogenic anovulation can be used to diagnose polycystic ovary syndrome (PCOS) in adolescents, according to a review article published online Nov. 23 in Pediatrics.

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Comorbid Stress, Depressive Symptoms Common in Diabetes

MONDAY, Nov. 23, 2015 (HealthDay News) -- For individuals with diabetes, comorbid stress and/or depressive symptoms are common and increase risks for adverse cardiovascular (CV) outcomes, according to a study published online Nov. 17 in Diabetes Care.

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Individual Glycemic Responses to Foods Found to Differ Greatly

MONDAY, Nov. 23, 2015 (HealthDay News) -- People have very different glycemic responses to the same food -- with some showing large blood glucose spikes even after eating supposedly healthy choices. Researchers said the findings, published in the Nov. 19 issue of Cell, underscore the message that there is no "one-size-fits-all" diet.

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Aetna Offers Targeted Health Plans for Diabetes Care

FRIDAY, Nov. 20, 2015 (HealthDay News) -- Aetna is offering targeted diabetes plans, which include low copays for specialists that patients with diabetes need, as well as free supplies and a care management program, according to a report published by Kaiser Health News.

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Terlipressin Therapy Can Induce Hyponatremia

FRIDAY, Nov. 20, 2015 (HealthDay News) -- Terlipressin therapy can induce hyponatremia, according to a case report published online Nov. 17 in the Journal of Clinical Pharmacy and Therapeutics.

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Genetic Risk Score Can Differentiate Type 1, 2 Diabetes

FRIDAY, Nov. 20, 2015 (HealthDay News) -- A genetic risk score (GRS) can distinguish type 1 diabetes (T1D) from type 2 diabetes (T2D), according to a study published online Nov. 17 in Diabetes Care.

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E-Portfolio Developed to Assess Millennial Med Students

THURSDAY, Nov. 19, 2015 (HealthDay News) -- Electronic portfolios are being used to transform medical students' assessments and track progress as students advance through medical training, according to a report published by the American Medical Association (AMA).

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Social Jetlag Tied to Prediabetes, Cardiovascular Disease Risk

THURSDAY, Nov. 19, 2015 (HealthDay News) -- Social jetlag due to a habitual discrepancy between endogenous circadian rhythm and actual sleep times, imposed by social obligations, is associated with metabolic risk factors that are linked to cardiovascular disease and prediabetes, according to a study published online Nov. 18 in the Journal of Clinical Endocrinology & Metabolism.

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Maintenance of LDL, HbA1c Goals With Pharmacist-Led Program

THURSDAY, Nov. 19, 2015 (HealthDay News) -- Veterans with type 2 diabetes had durable maintenance of their low-density lipoprotein (LDL) cholesterol and hemoglobin A1c (A1C) goals, but not systolic blood pressure (SBP) goals, after discharge from a pharmacist-managed ambulatory care clinic, in a study published in the November issue of Diabetes Spectrum.

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Diabetes Predicts Worse Survival in Renal Cell Carcinoma

THURSDAY, Nov. 19, 2015 (HealthDay News) -- Diabetes mellitus is associated with worse prognosis in terms of progression-free, overall, and cancer-specific survival in patients with renal cell carcinoma treated surgically, according to a study published in the December issue of The Journal of Urology.

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Successful Pregnancies Seen With Transfer of Mosaic Embryos

THURSDAY, Nov. 19, 2015 (HealthDay News) -- Embryos with a mix of normal and abnormal chromosomes implanted during in vitro fertilization (IVF) can develop into healthy newborns, a small new study suggests. The research was published in the Nov. 19 issue of the New England Journal of Medicine.

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Sildenafil Improves Insulin Sensitivity in Prediabetes

WEDNESDAY, Nov. 18, 2015 (HealthDay News) -- For patients with prediabetes, three-month sildenafil treatment improves insulin sensitivity, according to a study published online Nov. 18 in the Journal of Clinical Endocrinology & Metabolism.

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Pioglitazone Found to Help Some With Unremitting Depression

WEDNESDAY, Nov. 18, 2015 (HealthDay News) -- A new small study is adding evidence to the theory that insulin resistance may play a leading role in some cases of depression. Findings from the study were published online Oct. 12 in Psychiatry Research.

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Group Medicine Appointments Effective for Glycemic Control

WEDNESDAY, Nov. 18, 2015 (HealthDay News) -- Medical management delivered via group medical appointments (GMAs) appears to be effective for glycemic control in patients with type 2 diabetes, according to research published in the November issue of Diabetes Spectrum.

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Burnout Reduces Readiness to Change Teaching Approaches

WEDNESDAY, Nov. 18, 2015 (HealthDay News) -- Occupational burnout appears to reduce clinical faculty members' readiness to change teaching approaches, according to a study published online Nov. 13 in the Journal of Evaluation in Clinical Practice.

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AAFP: Expected 0.5 Percent Pay Increase Reduced to Zero

WEDNESDAY, Nov. 18, 2015 (HealthDay News) -- A small but promised Medicare pay increase has effectively been reduced to zero for all physician specialties, according to the final 2016 Medicare physician fee schedule and a report published by the American Academy of Family Physicians.

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Testosterone Levels Not Linked to Autonomic Neuropathy in T1DM

TUESDAY, Nov. 17, 2015 (HealthDay News) -- For men with type 1 diabetes, testosterone levels are not associated with cardiovascular autonomic neuropathy (CAN), according to a study published online Nov. 12 in The Journal of Sexual Medicine.

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GLP-1 Receptor Agonists Can Manage Postprandial Glucose

TUESDAY, Nov. 17, 2015 (HealthDay News) -- Glucagon-like peptide 1 (GLP-1) receptor agonists appear beneficial for postprandial glucose management in type 2 diabetes, according to a report published in the October issue of Clinical Diabetes.

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HbA1c Control on Metformin Predicts Durable Control in T2DM

MONDAY, Nov. 16, 2015 (HealthDay News) -- For adolescents with type 2 diabetes, hemoglobin A1c (HbA1c) after metformin monotherapy predicts the likelihood of durable glycemic control on oral therapy, according to a study published online Nov. 4 in Diabetes Care.

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Primary Aldosteronism Screen Cost-Effective in Resistant HTN

MONDAY, Nov. 16, 2015 (HealthDay News) -- For patients with resistant hypertension (RH), computed tomography (CT) scanning followed by adrenal venous sampling (AVS) is a cost-effective screen for primary aldosteronism (PA), according to a study published online Nov. 10 in Circulation: Cardiovascular Quality and Outcomes.

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Risk of Fractures Reduced in Polycystic Ovary Syndrome

MONDAY, Nov. 16, 2015 (HealthDay News) -- The risk of fractures is reduced in women with polycystic ovary syndrome (PCOS), according to a study published online Nov. 6 in the Journal of Bone and Mineral Research.

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Urinary Potassium Excretion Tied to Renal, Cardio Risk in T2DM

FRIDAY, Nov. 13, 2015 (HealthDay News) -- For patients with type 2 diabetes, higher urinary potassium excretion is associated with decreased risk of renal and cardiovascular events, according to a study published online Nov. 12 in the Clinical Journal of the American Society of Nephrology.

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Genetic Risk Score IDs Insulin Resistance, Change in IR

FRIDAY, Nov. 13, 2015 (HealthDay News) -- A genetic risk score based on 17 established insulin resistance (IR) variants and their effect sizes (weighted IR-GRS) is associated with IR at baseline and change in IR, but does not impact the effect of lifestyle intervention and metformin on IR, according to a study published online Nov. 2 in Diabetes.

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CDC: Adult Obesity Still Rising in U.S., Youth Rates Hold Steady

THURSDAY, Nov. 12, 2015 (HealthDay News) -- Although obesity rates continued to climb among U.S. adults over the past decade, they stabilized for children and teens, according to a November data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics.

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Risk Prediction Equations Created for Diabetes Complications

THURSDAY, Nov. 12, 2015 (HealthDay News) -- New risk prediction equations have been developed and validated to estimate the risk of blindness and lower limb amputation in patients with diabetes, according to a study published online Nov. 11 in The BMJ.

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Newborn Probiotic Use Tied to Lower Risk of Type 1 Diabetes

THURSDAY, Nov. 12, 2015 (HealthDay News) -- Adding probiotics to an infant's feedings in the first month of life may reduce the risk of type 1 diabetes for those genetically predisposed to the disease, according to research published online Nov. 9 in JAMA Pediatrics.

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Incretin Use May Up Pancreatic CA Risk, but Only in Short Term

THURSDAY, Nov. 12, 2015 (HealthDay News) -- The risk of pancreatic cancer is increased in recent starters of incretins, but the elevated risk drops to baseline levels with prolonged use, according to a study published online Nov. 5 in Diabetes, Obesity and Metabolism.

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Noon Best Time to Get Vitamin D From Sun for Minimal Cancer Risk

THURSDAY, Nov. 12, 2015 (HealthDay News) -- Variations in ultraviolet (UV) A and B radiation with increasing latitude and during the day impact skin cancer risk, according to a study published online Nov. 6 in the International Journal of Dermatology.

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ACP Issues Guidance on 'Concierge' Practices

TUESDAY, Nov. 10, 2015 (HealthDay News) -- Direct patient contracting practices (DPCPs), in which patients pay out of pocket for some or all services provided by the practice, are growing in popularity, according to a position paper published online Nov. 10 in the Annals of Internal Medicine.

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Central Obesity Is Hazardous, Even at a Normal Weight

WEDNESDAY, Nov. 11, 2015 (HealthDay News) -- Individuals with central obesity but of normal weight according to body mass index (BMI) have a higher risk of premature mortality than overweight or obese people, according to research published online Nov. 10 in the Annals of Internal Medicine.

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Few Adults With Severe Mental Illness Screened for Diabetes

WEDNESDAY, Nov. 11, 2015 (HealthDay News) -- About 30 percent of adults with severe mental illness (SMI) taking antipsychotic medications undergo diabetes-specific screening using validated screening measures, according to a study published online Nov. 9 in JAMA Internal Medicine.

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Insulin Pumps Offer Better HbA1c Control for Children With T1DM

WEDNESDAY, Nov. 11, 2015 (HealthDay News) -- Insulin pumps help improve hemoglobin A1C (HbA1c) levels in children and teens with type 1 diabetes and should be made more widely available, researchers report. The study was published online Nov. 7 in Diabetologia.

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Three Renal Biomarkers Predict Outcome in Diabetes

TUESDAY, Nov. 10, 2015 (HealthDay News) -- Three renal biomarkers, acute kidney injury (AKI), albuminuria, and low estimated glomerular filtration rate (eGFR), considered separately or together, can predict adverse outcomes in diabetes, according to a study published online Oct. 28 in Diabetes Care.

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Expanding Rooming, Discharge Office Protocols Can Save Time

MONDAY, Nov. 9, 2015 (HealthDay News) -- Expanding protocols for rooming and discharge can allow physicians to free up an hour or more of time per day, according to the American Medical Association (AMA).

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Study Explores Comfort With Non In-Person Test Results

MONDAY, Nov. 9, 2015 (HealthDay News) -- Patients have different preferences for non in-person receipt of test results, with preferences varying by test, according to a study published in the November-December issue of the Journal of the American Board of Family Medicine.

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Web-Based CBT Program Cuts Suicidal Ideation in Interns

MONDAY, Nov. 9, 2015 (HealthDay News) -- A web-based cognitive behavioral therapy (wCBT) program is effective for preventing suicidal ideation among medical interns, according to a study published online Nov. 4 in JAMA Psychiatry.

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Specific Insulin-Based Exercise Strategies Help in T1DM Pump Tx

FRIDAY, Nov. 6, 2015 (HealthDay News) -- Insulin-based strategies of basal rate reduction or pump cessation may be the best approach in avoiding hypoglycemia associated with exercise after lunch, according to a study published online Oct. 8 in Diabetes, Obesity & Metabolism.

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Updated Checklist for Reporting Diagnostic Accuracy Studies

FRIDAY, Nov. 6, 2015 (HealthDay News) -- An updated list of 30 essential items should be included in every report of a diagnostic accuracy study, according to the Standards for Reporting Diagnostic Accuracy Studies (STARD) 2015. These new guidelines have been published in several journals, including Radiology, Clinical Chemistry, and The BMJ.

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Poll: Americans Want Health Care Costs Kept in Check

THURSDAY, Nov. 5, 2015 (HealthDay News) -- Most Americans now support aggressive regulation to keep health care costs in check -- including price caps on drugs, medical devices, and payments to doctors and hospitals, a new HealthDay/Harris Poll has found.

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Doctors Who Order More Tests Have Fewer Malpractice Claims

THURSDAY, Nov. 5, 2015 (HealthDay News) --The more tests and treatments U.S. doctors order for patients, the less likely they are to be sued for malpractice, according to a study published online Nov. 4 in The BMJ.

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Metformin Eligibility Up With eGFR Versus Serum Creatinine

THURSDAY, Nov. 5, 2015 (HealthDay News) -- Use of estimated glomerular filtration rate (eGFR) rather than serum creatinine (sCr) can expand metformin eligibility, according to a study published in the November issue of Diabetes Care.

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ACP Joins Amicus Curiae Brief to Supreme Court

THURSDAY, Nov. 5, 2015 (HealthDay News) -- The American College of Physicians (ACP) has joined other organizations in an amicus curiae brief to the Supreme Court, urging the court to uphold considerations of race and ethnicity in the medical school admissions process.

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Sleep Patterns May Affect a Woman's Diabetes Risk

WEDNESDAY, Nov. 4, 2015 (HealthDay News) -- Women who experience a big increase in hours of sleep each night may face an increased risk of type 2 diabetes, new research suggests. The study appeared online Nov. 2 in Diabetologia.

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Adherence, Not Diet Type, Predicts Long-Term Weight Loss

WEDNESDAY, Nov. 4, 2015 (HealthDay News) -- Low-fat diets are no more effective than other types of diets for long-term weight loss, according to a review published online Oct. 29 in The Lancet Diabetes & Endocrinology.

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Doctors Should Consider Financial Factors Before Career Change

WEDNESDAY, Nov. 4, 2015 (HealthDay News) -- Financial and other factors should be considered before physicians change career direction, according to a report published in Medical Economics.

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AMA: 6 Steps to Help Ensure Patients Get Preventive Care

WEDNESDAY, Nov. 4, 2015 (HealthDay News) -- Panel management, or population health management, can help physicians provide necessary preventive and chronic care to all patients regardless of their visit frequency, according to a report published by the American Medical Association (AMA).

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SLC16A11 Linked to Type 2 Diabetes in American Indians

WEDNESDAY, Nov. 4, 2015 (HealthDay News) -- SLC16A11 A allele is modestly associated with type 2 diabetes in North American Indians, according to a study published online Oct. 20 in Diabetes.

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Guideline-Concordant Diabetes Care Similar With NPs, PCPs

WEDNESDAY, Nov. 4, 2015 (HealthDay News) -- The rates of processes of diabetes mellitus guideline-concordant care are similar, or slightly lower, for nurse practitioners (NPs) versus primary care physicians (PCPs), according to a study published in the October issue of the Journal of the American Geriatrics Society.

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Prescription Medication Use on the Rise in the United States

WEDNESDAY, Nov. 4, 2015 (HealthDay News) -- More Americans than ever are taking prescription drugs, as well as using more of them, according to research published in the Nov. 3 issue of the Journal of the American Medical Association.

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GDM Risk Higher With More Abdominal Fat in First Trimester

TUESDAY, Nov. 3, 2015 (HealthDay News) -- Women with high levels of abdominal fat in their first trimester are at increased risk for diabetes later in pregnancy, according to research published online Nov. 2 in Diabetes Care.

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New Electronic Health Record Regulations Released

TUESDAY, Nov. 3, 2015 (HealthDay News) -- New electronic health record (EHR) regulations modify Stage 2 of the meaningful use program and finalize requirements for Stage 3, according to a report published by the American Medical Association (AMA).

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Severe Obesity in Adults Costs Medicaid $8 Billion Annually

TUESDAY, Nov. 3, 2015 (HealthDay News) -- Severe obesity is putting a huge financial strain on both the U.S. Medicaid system and severely obese patients themselves, according to a report published in the November issue of Health Affairs.

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Chronic PPI Exposure Tied to Hyperparathyroidism in Elderly

TUESDAY, Nov. 3, 2015 (HealthDay News) -- Chronic proton pump inhibitor (PPI) exposure is associated with mild hyperparathyroidism in elderly adults, according to a study published in the October issue of the Journal of the American Geriatrics Society.

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Stem/Progenitor Cells Can Predict Wound Healing

TUESDAY, Nov. 3, 2015 (HealthDay News) -- Stem/progenitor cell (SPC) assays can predict wound healing in diabetic foot ulcers (DFUs), according to a study published online Oct. 20 in Diabetes.

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Prescribing Drugs 'Off-Label' Can Pose Serious Safety Risks

MONDAY, Nov. 2, 2015 (HealthDay News) -- Off-label drug use puts patients at risk for serious side effects, especially when scientific evidence is lacking, according to a study published online Nov. 2 in JAMA Internal Medicine.

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Competition for Fellowships Broke Records in 2015

MONDAY, Nov. 2, 2015 (HealthDay News) -- According to the American Medical Association (AMA), 2015 was a record-breaking year for fellowship applications.

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High-Intensity Interval Training Improves Metabolic Health

MONDAY, Nov. 2, 2015 (HealthDay News) -- High-intensity interval training (HIIT) seems to be beneficial for improving metabolic health, according to a meta-analysis published in the November issue of Obesity Reviews.

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Displaying Prices to Providers Seems to Reduce Order Costs

MONDAY, Nov. 2, 2015 (HealthDay News) -- Displaying order prices to physicians seems to reduce order costs, according to a review published online Oct. 23 in the Journal of Hospital Medicine.

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Case Study: Bisphosphonate-Linked Osteonecrosis in Diabetes

MONDAY, Nov. 2, 2015 (HealthDay News) -- A case of bisphosphonate-related osteonecrosis of the jaw is described in an elderly patient with diabetes mellitus. The report is published in the October issue of the Journal of the American Geriatrics Society.

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Prediabetes Linked to Incident Cardiovascular Disease

MONDAY, Nov. 2, 2015 (HealthDay News) -- Prediabetes is associated with incident cardiovascular disease (CVD), although correlations vary with ethnicity and prediabetes definition, according to a study published online Oct. 20 in Diabetes Care.

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