Non-O Blood Group Tied to Higher CAD, MI Risk

This article originally appeared here.
Share this content:
Non-O Blood Group Tied to Higher CAD, MI Risk
Non-O Blood Group Tied to Higher CAD, MI Risk

WEDNESDAY, Sept. 9, 2015 (HealthDay News) -- Having non-O blood group may be an independent risk factor for coronary artery disease (CAD) and myocardial infarction, according to a meta-analysis published in the Sept. 1 issue of The American Journal of Cardiology.

Hisato Takagi, M.D., Ph.D., and Takuya Umemoto, M.D., Ph.D., on behalf of the All-Literature Investigation of Cardiovascular Evidence Group, conducted a literature review (January 2001 to March 2015) to identify case-control, cross-sectional, or cohort studies reporting adjusted odds ratios (ORs) and hazard ratios (HRs) for CAD in subjects with non-O versus O blood group.

The researchers included 12 relative risk estimates in 10 eligible studies. Based on pooled analysis, the non-O blood group was associated with a statistically significant 14 percent increase in CAD incidence compared to O blood group (OR/HR, 1.14). No evidence of significant publication bias was seen. When eight studies reporting data regarding (acute) myocardial infarction (MI) were pooled, similar statistically significant results unfavorable to the non-O blood group were seen (OR/HR, 1.16).

"In conclusion, we found that based on a meta-analysis of 10 studies enrolling a total of 174,945 participants, non-O blood group appears to be an independent risk factor for CAD and MI," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease


More in Home

Insulin Glargine, Lixisenatide Combo Beneficial in T2DM

Insulin Glargine, Lixisenatide Combo Beneficial in T2DM

Improved achievement of glycemic targets, reduced body weight

European, American Guidelines Lead to Different Recs for Statins

European, American Guidelines Lead to Different Recs for ...

Quantification of CAC score can improve stratification for those at high, low risk for events

Hyperbaric O2 Therapy Effective in Maxillary Osteoradionecrosis

Hyperbaric O<sub>2</sub> Therapy Effective in Maxillary Osteoradionecrosis

Positive clinical outcome with HBOT for 85.7 percent of patients with maxillary bone osteoradionecrosis

is free, fast, and customized just for you!

Already a member?

Sign In Now »