No Safety Concerns Noted in Study of Intranasal Insulin Use

This article originally appeared here.
Share this content:
No Safety Concerns Noted in Study of Intranasal Insulin Use
No Safety Concerns Noted in Study of Intranasal Insulin Use

MONDAY, March 12, 2018 (HealthDay News) -- Intranasal insulin application appears to be safe, according to a review published online March 6 in Diabetes, Obesity and Metabolism.

Vera Schmid, from the University of Tübingen in Germany, and colleagues conducted a systematic literature search to identify original research on the use of intranasal human insulin without further additives in humans.

The researchers identified 38 studies (1,092 participants) with acute application and 18 studies (832 participants) with treatment lasting between 21 days and 9.7 years. There were no cases of symptomatic hypoglycemia or severe adverse events identified. After both intranasal insulin and placebo spray, transient local side effects in the nasal area were frequently experienced, but adverse events were less commonly reported. Tests on spray insulin showed it had a chemical stability of up to 57 days.

"Our retrospective review of published studies on intranasal insulin did not reveal any safety concerns. There is, however, insufficient data to ensure long-term safety of this modality of chronic insulin administration," the authors write. "Improved insulin preparations that cause less nasal irritation would be desirable for future treatment."

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease



Sign up for myCME e-newsletters




More in Home

FDA Approves First Generic Under-the-Tongue Suboxone

FDA Approves First Generic Under-the-Tongue Suboxone

May only be prescribed by Drug Addiction Treatment Act-certified prescribers

Kellogg's Honey Smacks Cereal Recalled Due to Salmonella Risk

Kellogg's Honey Smacks Cereal Recalled Due to <i>Salmonella</i> ...

Twenty-four people have been hospitalized, but no deaths have been reported

Portable Music Player Use Linked to Hearing Loss in Children

Portable Music Player Use Linked to Hearing Loss ...

Increased odds of high-frequency hearing loss with portable music player use

is free, fast, and customized just for you!




Already a member?

Sign In Now »