Nitrofurantoin Not Best Choice for UTIs in Older Women

This article originally appeared here.
Share this content:
Nitrofurantoin Not Best Choice for UTIs in Older Women
Nitrofurantoin Not Best Choice for UTIs in Older Women

FRIDAY, May 1, 2015 (HealthDay News) -- Nitrofurantoin may not be the most effective option for treatment of urinary tract infections in older women, according to a new study published online April 27 in CMAJ, the journal of the Canadian Medical Association.

The research was led by Amit Garg, M.D., Ph.D., a nephrologist at Western University in London, Canada. His team compared the benefits of nitrofurantoin to the effectiveness of other commonly used antibiotics such as ciprofloxacin and norfloxicin. The study involved 9,223 older women with impaired kidney function and 182,634 women with normal kidney function.

The researchers found that nitrofurantoin was less successful than other drugs in treating urinary tract infections among all of the women in the study -- not just those with reduced kidney function. What's more, the results of the study suggest that use of nitrofurantoin for urinary tract infections among older women may boost the odds the patient will require a second round of treatment with another antibiotic or a trip to the hospital, the researchers said.

"In our setting, nitrofurantoin was the most commonly prescribed antibiotic for a urinary tract infection in older women irrespective of their kidney function," Garg said in a journal news release. "These patients had more treatment failures with nitrofurantoin compared with other antibiotics such as ciprofloxacin," he added. "However, this was evident regardless of a patient's level of kidney function."

Abstract
Full Text

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters




More in Home

Congress Approves Bill Expanding Private Care for VA Patients

Congress Approves Bill Expanding Private Care for VA ...

New bill would open up access to private doctors for veterans

AAP Recommending Injectable Flu Shot for 2018-19 Flu Season

AAP Recommending Injectable Flu Shot for 2018-19 Flu ...

Children should receive injectable vaccine, which has been shown to be more consistently effective

Neurologists Identify New Type of Vertigo

Neurologists Identify New Type of Vertigo

Long-term prognosis favorable, with improvement of symptoms in more than half of patients