New Rx Strategy May Up Survival in Advanced Prostate Cancer

This article originally appeared here.
Share this content:
New Rx Strategy May Up Survival in Advanced Prostate Cancer
New Rx Strategy May Up Survival in Advanced Prostate Cancer

THURSDAY, Aug. 6, 2015 (HealthDay News) -- Chemotherapy at the start of androgen-deprivation therapy (ADT) can extend the lives of men with metastatic, hormone-sensitive prostate cancer, according to research published online Aug. 5 in the New England Journal of Medicine.

Christopher Sweeney, M.B., B.S., an associate professor of medicine at Harvard Medical School in Boston, and colleagues randomly assigned 790 men with prostate cancer, average age 63, to ADT plus docetaxel or ADT alone.

Over nearly 29 months of follow-up, men with advanced prostate cancer who received the combination therapy lived almost 14 months longer than men who received only ADT (57.6 versus 44.0 months). In addition to the survival benefit, men who received the combination of docetaxel and ADT remained progression-free for 20.2 months, compared with 11.7 months among those who only received ADT.

Sweeney told HealthDay that side effects of the chemotherapy were mild, in general. Fatigue, neutropenia, and infection were the most common side effects, the study authors found. One man died from an unknown cause, though the researchers said the death may have been due to the chemotherapy.

Several authors disclosed financial ties to pharmaceutical companies, including Sanofi, which provided the docetaxel for the study.

Abstract
Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters


More in Home

Pharmacists Should Counsel Patients Fasting for Ramadan

Pharmacists Should Counsel Patients Fasting for Ramadan

Pharmacists can suggest adjustments for meds taken several times per day, those affected by food intake

AUA: Many Have Unused Opioids After Urologic Procedures

AUA: Many Have Unused Opioids After Urologic Procedures

Patients use just over half of initial prescription; highest percentage of unused meds for cystectomy

Over Half of Young Adult Smoke Volume Exposure From Hookahs

Over Half of Young Adult Smoke Volume Exposure ...

Toxicant exposure to tar, carbon monoxide, nicotine lower, but still substantial, compared to cigarettes

is free, fast, and customized just for you!

Already a member?

Sign In Now »