New Recs for RBC Transfusion, Optimal RBC Storage Length

Share this content:
New Recs for RBC Transfusion, Optimal RBC Storage Length
New Recs for RBC Transfusion, Optimal RBC Storage Length

MONDAY, Oct. 17, 2016 (HealthDay News) -- In a clinical practice guideline published online Oct. 12 in the Journal of the American Medical Association, recommendations are presented for the target hemoglobin level for red blood cell (RBC) transfusion and optimal duration of RBC storage.

Jeffrey L. Carson, M.D., from Rutgers University in New Brunswick, N.J., and colleagues developed recommendations for the target hemoglobin level for RBC transfusion among hospitalized adult patients who are hemodynamically stable, as well as optimal storage time for RBCs prior to transfusion. Data were reviewed from randomized clinical trials (RCTs) evaluating hemoglobin thresholds for RBC transfusion (31 RCTs with 12,587 participants) and RBC storage duration (13 RCTs with 5,515 participants).

The researchers note that when making transfusion decisions regarding an individual patient, the hemoglobin level, overall clinical context, patient preferences, and alternative therapies should be considered. For hospitalized adults who are hemodynamically stable, including critically ill patients, a restrictive RBC transfusion threshold in which transfusion is not indicated until the hemoglobin level is 7 g/dL is recommended. For patients undergoing orthopedic and cardiac surgery and those with preexisting cardiac disease, a restrictive RBC transfusion threshold of 8 g/dL is recommended. Patients should receive RBC units selected at any point within their licensed dating period (storage length: <10 days).

"A restrictive transfusion threshold is safe in most clinical settings and the current blood banking practices of using standard-issue blood should be continued," the authors write.

Several authors disclosed financial ties to the pharmaceutical and medical technology industries.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions


Sign up for myCME e-newsletters


More in Home

Automated Central System Offers Time Savings for Pharmacists

Automated Central System Offers Time Savings for Pharmacists

Cart-fill process using new automated system is more efficient, frees up time for other roles

Therapeutic Horseback Riding Can Help Alleviate PTSD in Veterans

Therapeutic Horseback Riding Can Help Alleviate PTSD in ...

Study found statistically and clinically significant reduction in PTSD scores after six weeks of THR

Bariatric Surgery Linked to Discontinuing Diabetes Meds

Bariatric Surgery Linked to Discontinuing Diabetes Meds

Six-year antidiabetes treatment initiation rate also much lower after bariatric surgery

is free, fast, and customized just for you!

Already a member?

Sign In Now »