New Class of Migraine Meds Shows Promise for Prevention

Share this content:
New Class of Migraine Meds Shows Promise for Prevention
New Class of Migraine Meds Shows Promise for Prevention

THURSDAY, June 18, 2015 (HealthDay News) -- Results from phase II clinical trials indicate that a new class of drugs, calcitonin gene-related peptide (CGRP) monoclonal antibodies, can effectively prevent migraine in a substantial portion of patients. Findings from these studies were to be presented this week at the annual meeting of the American Headache Society, held from June 18 to 21 in Washington, D.C.

This latest class of drugs reduces levels of CGRP, a key driver of migraine. Four drug manufacturers -- Alder Pharmaceuticals, Amgen, Eli Lilly and Company, and Teva Pharmaceuticals -- currently are testing their own versions of CGRP monoclonal antibodies.

In results presented at the American Headache Society meeting: Teva reported that its drug achieved a significant reduction in the number of headache hours after one week, with more than half of patients in each arm experiencing a 50 percent or greater reduction in headache frequency. Amgen reported that its drug reduced the number of migraine days by 50 percent in about half the treated patients after 12 weeks. Lilly showed that its drug could help prevent migraine headaches, compared to placebo.

Alder Pharmaceuticals didn't present any new findings at the meeting, but has previously published promising phase II study results, according to an American Headache Society news release.

Press Release
More Information

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions



Sign up for myCME e-newsletters


More in Home

AAP: Congress Urged to Act to Prevent Firearm Deaths

AAP: Congress Urged to Act to Prevent Firearm ...

Following latest shooting, pediatricians join call for action to be taken to address firearm deaths, injury

Lung Cancer Incidence Higher for Young Women Than Young Men

Lung Cancer Incidence Higher for Young Women Than ...

Crossover in sex-specific rates among U.S. non-Hispanic whites born since 1965

E-Cigarette Flavoring Agent May Impair Airway Defense System

E-Cigarette Flavoring Agent May Impair Airway Defense System

Flavoring commonly used in e-cigarettes suppresses cilia beat frequency, lasting for 60 minutes

is free, fast, and customized just for you!

Already a member?

Sign In Now »