Neonatal Phototherapy Not Linked to Type 1 Diabetes

Share this content:
Neonatal Phototherapy Not Linked to Type 1 Diabetes
Neonatal Phototherapy Not Linked to Type 1 Diabetes

THURSDAY, Oct. 20, 2016 (HealthDay News) -- Neonatal phototherapy is not associated with type 1 diabetes mellitus (DM-1), according to a study published online Oct. 19 in Pediatrics.

Thomas B. Newman, M.D., M.P.H., from the University of California in San Francisco, and colleagues conducted a retrospective cohort study involving 499,642 children born at ≥35 weeks of gestation from 1995 to 2011. Phototherapy, bilirubin levels, and other covariates were ascertained from electronic records. A diabetes registry and inpatient and outpatient diagnoses were used to identify DM-1 cases.

The researchers observed an increase in phototherapy use from 2.7 percent in 1995 to 16.0 percent in 2011. DM-1 was diagnosed in 37 of 39,406 children who had received phototherapy and in 712 of 460,236 who had not (15.1 versus 18.8 per 100,000 person-years). No evidence was found for increasing incidence of diabetes. Phototherapy was not associated with DM-1 in unadjusted analyses (incidence rate ratio, 0.81; 95 percent confidence interval, 0.56 to 1.12) or after adjustment for hyperbilirubinemia and other covariates (hazard ratio, 1.06; 95 percent confidence interval, 0.78 to 1.45). The strongest correlation for DM-1 incidence was seen for race and ethnicity, with the highest risk for whites (25.6 per 100,000) and lowest risk for Asians (8.9 per 100,000).

"We found no evidence of increased DM-1 risk in children who had received phototherapy," the authors write.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions


Sign up for myCME e-newsletters


More in Home

Structural Findings of Acute Solar Retinopathy Described

Structural Findings of Acute Solar Retinopathy Described

Patient in case study presented three days after viewing solar eclipse

Telomere Fusions Predict Dysplasia, Invasive Pancreatic CA

Telomere Fusions Predict Dysplasia, Invasive Pancreatic CA

Telomere fusions are detected in later stages of intraductal papillary mucinous neoplasm progression

Prenatal Sugar Intake May Increase Asthma Risk in Offspring

Prenatal Sugar Intake May Increase Asthma Risk in ...

Higher intake during pregnancy, in early childhood associated with childhood asthma development

is free, fast, and customized just for you!

Already a member?

Sign In Now »